KEGG   Vulpes vulpes (red fox): 112920790
Entry
112920790         CDS       T05911                                 

Gene name
GRB2
Definition
(RefSeq) growth factor receptor-bound protein 2
  KO
K04364  growth factor receptor-bound protein 2
Organism
vvp  Vulpes vulpes (red fox)
Pathway
vvp01521  EGFR tyrosine kinase inhibitor resistance
vvp01522  Endocrine resistance
vvp04010  MAPK signaling pathway
vvp04012  ErbB signaling pathway
vvp04014  Ras signaling pathway
vvp04062  Chemokine signaling pathway
vvp04068  FoxO signaling pathway
vvp04072  Phospholipase D signaling pathway
vvp04150  mTOR signaling pathway
vvp04151  PI3K-Akt signaling pathway
vvp04380  Osteoclast differentiation
vvp04510  Focal adhesion
vvp04540  Gap junction
vvp04550  Signaling pathways regulating pluripotency of stem cells
vvp04630  JAK-STAT signaling pathway
vvp04650  Natural killer cell mediated cytotoxicity
vvp04660  T cell receptor signaling pathway
vvp04662  B cell receptor signaling pathway
vvp04664  Fc epsilon RI signaling pathway
vvp04714  Thermogenesis
vvp04722  Neurotrophin signaling pathway
vvp04910  Insulin signaling pathway
vvp04912  GnRH signaling pathway
vvp04915  Estrogen signaling pathway
vvp04917  Prolactin signaling pathway
vvp04926  Relaxin signaling pathway
vvp04935  Growth hormone synthesis, secretion and action
vvp05034  Alcoholism
vvp05160  Hepatitis C
vvp05161  Hepatitis B
vvp05163  Human cytomegalovirus infection
vvp05165  Human papillomavirus infection
vvp05200  Pathways in cancer
vvp05203  Viral carcinogenesis
vvp05205  Proteoglycans in cancer
vvp05206  MicroRNAs in cancer
vvp05210  Colorectal cancer
vvp05211  Renal cell carcinoma
vvp05213  Endometrial cancer
vvp05214  Glioma
vvp05215  Prostate cancer
vvp05220  Chronic myeloid leukemia
vvp05221  Acute myeloid leukemia
vvp05223  Non-small cell lung cancer
vvp05224  Breast cancer
vvp05225  Hepatocellular carcinoma
vvp05226  Gastric cancer
vvp05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:vvp00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    112920790 (GRB2)
   04012 ErbB signaling pathway
    112920790 (GRB2)
   04014 Ras signaling pathway
    112920790 (GRB2)
   04630 JAK-STAT signaling pathway
    112920790 (GRB2)
   04068 FoxO signaling pathway
    112920790 (GRB2)
   04072 Phospholipase D signaling pathway
    112920790 (GRB2)
   04151 PI3K-Akt signaling pathway
    112920790 (GRB2)
   04150 mTOR signaling pathway
    112920790 (GRB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    112920790 (GRB2)
   04540 Gap junction
    112920790 (GRB2)
   04550 Signaling pathways regulating pluripotency of stem cells
    112920790 (GRB2)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    112920790 (GRB2)
   04660 T cell receptor signaling pathway
    112920790 (GRB2)
   04662 B cell receptor signaling pathway
    112920790 (GRB2)
   04664 Fc epsilon RI signaling pathway
    112920790 (GRB2)
   04062 Chemokine signaling pathway
    112920790 (GRB2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    112920790 (GRB2)
   04912 GnRH signaling pathway
    112920790 (GRB2)
   04915 Estrogen signaling pathway
    112920790 (GRB2)
   04917 Prolactin signaling pathway
    112920790 (GRB2)
   04926 Relaxin signaling pathway
    112920790 (GRB2)
   04935 Growth hormone synthesis, secretion and action
    112920790 (GRB2)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    112920790 (GRB2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    112920790 (GRB2)
  09159 Environmental adaptation
   04714 Thermogenesis
    112920790 (GRB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    112920790 (GRB2)
   05206 MicroRNAs in cancer
    112920790 (GRB2)
   05205 Proteoglycans in cancer
    112920790 (GRB2)
   05203 Viral carcinogenesis
    112920790 (GRB2)
   05231 Choline metabolism in cancer
    112920790 (GRB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    112920790 (GRB2)
   05225 Hepatocellular carcinoma
    112920790 (GRB2)
   05226 Gastric cancer
    112920790 (GRB2)
   05214 Glioma
    112920790 (GRB2)
   05221 Acute myeloid leukemia
    112920790 (GRB2)
   05220 Chronic myeloid leukemia
    112920790 (GRB2)
   05211 Renal cell carcinoma
    112920790 (GRB2)
   05215 Prostate cancer
    112920790 (GRB2)
   05213 Endometrial cancer
    112920790 (GRB2)
   05224 Breast cancer
    112920790 (GRB2)
   05223 Non-small cell lung cancer
    112920790 (GRB2)
  09165 Substance dependence
   05034 Alcoholism
    112920790 (GRB2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    112920790 (GRB2)
   05160 Hepatitis C
    112920790 (GRB2)
   05163 Human cytomegalovirus infection
    112920790 (GRB2)
   05165 Human papillomavirus infection
    112920790 (GRB2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    112920790 (GRB2)
   01522 Endocrine resistance
    112920790 (GRB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:vvp04131]
    112920790 (GRB2)
  09183 Protein families: signaling and cellular processes
   04990 Domain-containing proteins not elsewhere classified [BR:vvp04990]
    112920790 (GRB2)
Membrane trafficking [BR:vvp04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Receptor tyrosine kinase (RTK) adaptor proteins
    112920790 (GRB2)
Domain-containing proteins not elsewhere classified [BR:vvp04990]
 Src homology (SH) domain-containing proteins
  Signal transducing adaptor proteins
   112920790 (GRB2)
SSDB
Motif
Pfam: SH3_1 SH3_9 SH3_2 SH2 SH3_10 SH2_2 SH3_3 DUF5093 hSH3 SH3_4
Other DBs
NCBI-GeneID: 112920790
NCBI-ProteinID: XP_025855511
UniProt: A0A0B4UGF9
LinkDB
Position
Unknown
AA seq 217 aa
MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPW
FFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFL
WVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRG
DFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV
NT seq 654 nt   +upstreamnt  +downstreamnt
atggaagccatcgccaaatatgacttcaaagccactgctgacgatgagctgagcttcaag
aggggggacatcctcaaggttttgaatgaagaatgtgatcagaactggtacaaggcagaa
ctcaacgggaaagatggcttcattcccaagaattacatagaaatgaaaccacatccgtgg
ttttttggcaaaatccccagagccaaggcagaagaaatgcttagcaaacagcggcatgac
ggggcctttctcatccgagagagtgagagtgcccccggggacttctccctctctgtcaag
tttggaaatgatgtgcagcacttcaaggtgctccgagatggagctgggaagtatttcctc
tgggtggtgaaattcaattctctgaacgagctggtcgattatcacagatctacatccgtc
tccagaaaccagcagatattcctccgggacatagaacaggtgccacagcaaccgacatac
gtccaggccctctttgactttgatccccaggaggatggagagctgggattccgtcgggga
gactttatccacgtcatggataactcagaccccaactggtggaaaggggcctgccatggg
caaaccggcatgtttccccgcaattacgtcacccctgtgaaccggaacgtctaa

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