Vulpes vulpes (red fox): 112922285 Help Entry 112922285         CDS       T05911                                  Gene name MDM2 Definition (RefSeq) E3 ubiquitin-protein ligase Mdm2   KO K06643   E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27] Organism vvp  Vulpes vulpes (red fox) Pathway vvp01522   Endocrine resistance vvp01524   Platinum drug resistance vvp04068   FoxO signaling pathway vvp04110   Cell cycle vvp04115   p53 signaling pathway vvp04120   Ubiquitin mediated proteolysis vvp04144   Endocytosis vvp04151   PI3K-Akt signaling pathway vvp04218   Cellular senescence vvp04625   C-type lectin receptor signaling pathway vvp04919   Thyroid hormone signaling pathway vvp05163   Human cytomegalovirus infection vvp05165   Human papillomavirus infection vvp05169   Epstein-Barr virus infection vvp05200   Pathways in cancer vvp05202   Transcriptional misregulation in cancer vvp05203   Viral carcinogenesis vvp05205   Proteoglycans in cancer vvp05206   MicroRNAs in cancer vvp05214   Glioma vvp05215   Prostate cancer vvp05218   Melanoma vvp05219   Bladder cancer vvp05220   Chronic myeloid leukemia Brite KEGG Orthology (KO) [BR:vvp00001]  09120 Genetic Information Processing   09123 Folding, sorting and degradation    04120 Ubiquitin mediated proteolysis     112922285 (MDM2)  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     112922285 (MDM2)    04151 PI3K-Akt signaling pathway     112922285 (MDM2)  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     112922285 (MDM2)   09143 Cell growth and death    04110 Cell cycle     112922285 (MDM2)    04115 p53 signaling pathway     112922285 (MDM2)    04218 Cellular senescence     112922285 (MDM2)  09150 Organismal Systems   09151 Immune system    04625 C-type lectin receptor signaling pathway     112922285 (MDM2)   09152 Endocrine system    04919 Thyroid hormone signaling pathway     112922285 (MDM2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     112922285 (MDM2)    05202 Transcriptional misregulation in cancer     112922285 (MDM2)    05206 MicroRNAs in cancer     112922285 (MDM2)    05205 Proteoglycans in cancer     112922285 (MDM2)    05203 Viral carcinogenesis     112922285 (MDM2)   09162 Cancer: specific types    05214 Glioma     112922285 (MDM2)    05220 Chronic myeloid leukemia     112922285 (MDM2)    05218 Melanoma     112922285 (MDM2)    05219 Bladder cancer     112922285 (MDM2)    05215 Prostate cancer     112922285 (MDM2)   09172 Infectious disease: viral    05163 Human cytomegalovirus infection     112922285 (MDM2)    05169 Epstein-Barr virus infection     112922285 (MDM2)    05165 Human papillomavirus infection     112922285 (MDM2)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     112922285 (MDM2)    01522 Endocrine resistance     112922285 (MDM2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:vvp04131]     112922285 (MDM2)    04121 Ubiquitin system [BR:vvp04121]     112922285 (MDM2) Enzymes [BR:vvp01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      112922285 (MDM2) Membrane trafficking [BR:vvp04131]  Endocytosis   Clathrin-mediated endocytosis    Ubiquitin E3 ligases     112922285 (MDM2) Ubiquitin system [BR:vvp04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    MDM2/MDM4 proteins     112922285 (MDM2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  zf-C3HC4_3 SWIB zf-RanBP CRT10 zf-RING_2 zf-FPG_IleRS Motif Other DBs NCBI-GeneID:  112922285 NCBI-ProteinID:  XP_025857531 UniProt:  A0A3Q7SPK8 LinkDB All DBs Position Unknown AA seq 432 aa AA seqDB search MCNTNMSVSTDGAVSTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVIFYLGQY IMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQHEEHADDL PGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGDW LDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEXYRVTVYQAGESDTDSFEGDP EISLADYWKCTSCNEMNPPLPPHCNRCWALRENWLPEDKGKIPEKATPENSTQVEEGFDV PDCKKTAASDSRESCAEEIDDKITQASHSQESEDYSQPSTSNSIIYSSQEDVKEFEREET QDKEEIVESSFPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCR QPIQMIVLTYFP NT seq 1299 nt NT seq  +upstreamnt  +downstreamnt atgtgcaataccaacatgtctgtgtctactgatggtgctgtaagcacctcacagattcca gcttcggagcaggagaccctggttagaccaaagccattgcttttgaagttgttgaagtct gtaggtgcacaaaaagacacttatactatgaaagaggtgatattctatcttggccagtat attatgactaaacgattgtatgatgagaagcaacagcatattgtgtattgttccaatgat cttctaggagatttgtttggagtgccaagcttctctgtgaaagagcacaggaaaatatat acaatgatctacagaaacttggtagtagtcaatcagcatgaagaacatgcagatgattta cctggtgaacggcagagaaagcgccacaaatctgatagtatttccctttcctttgatgaa agccttgctctgtgtgtaataagggagatatgttgtgaaagaagcagtagcagtgagtca acagggacgccatcaaatccggatcttgatgctggtgtaagtgaacattcaggtgattgg ttggatcaggattcagtttcagatcaattcagtgtagaatttgaagttgagtctcttgat tcagaagattatagccttagtgaagaaggacaagaactctcagatgaagatgatgagntg tatcgagtaactgtgtatcaggcaggggagagtgatacagattcatttgaaggagatcct gaaatttccttagctgactattggaagtgtacctcatgcaatgaaatgaatcctcctctt ccacctcattgcaatagatgttgggcccttcgtgagaattggcttcctgaagataaaggg aaaatccctgagaaagccacaccagaaaactcaacacaagtagaagagggctttgatgtc cctgattgtaaaaaaactgcagccagtgattccagagaatcatgtgctgaggaaattgat gataaaatcacacaagcctcccactcccaagaaagtgaggactattctcagccatcaact tctaacagcatcatttatagcagccaagaagatgtcaaggaatttgagagagaagaaaca caagacaaagaagaaattgtggaatctagttttccccttaatgccattgaaccttgtgtg atttgccaaggtcgacctaaaaacggttgcattgttcatggcaaaacaggacatcttatg gcatgcttcacgtgtgcaaagaagctaaagaaaaggaataagccctgtccagtatgtaga caaccaattcaaatgattgtgctaacttatttcccctaa

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