KEGG   Vulpes vulpes (red fox): 112931976Help
Entry
112931976         CDS       T05911                                 

Gene name
PTEN
Definition
(RefSeq) phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1
  KO
K01110  phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
Organism
vvp  Vulpes vulpes (red fox)
Pathway
vvp00562  Inositol phosphate metabolism
vvp01100  Metabolic pathways
vvp01521  EGFR tyrosine kinase inhibitor resistance
vvp04068  FoxO signaling pathway
vvp04070  Phosphatidylinositol signaling system
vvp04071  Sphingolipid signaling pathway
vvp04115  p53 signaling pathway
vvp04140  Autophagy - animal
vvp04150  mTOR signaling pathway
vvp04151  PI3K-Akt signaling pathway
vvp04218  Cellular senescence
vvp04510  Focal adhesion
vvp04931  Insulin resistance
vvp05165  Human papillomavirus infection
vvp05166  Human T-cell leukemia virus 1 infection
vvp05200  Pathways in cancer
vvp05206  MicroRNAs in cancer
vvp05213  Endometrial cancer
vvp05214  Glioma
vvp05215  Prostate cancer
vvp05218  Melanoma
vvp05222  Small cell lung cancer
vvp05224  Breast cancer
vvp05225  Hepatocellular carcinoma
vvp05230  Central carbon metabolism in cancer
vvp05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:vvp00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    112931976 (PTEN)
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    112931976 (PTEN)
   04070 Phosphatidylinositol signaling system
    112931976 (PTEN)
   04071 Sphingolipid signaling pathway
    112931976 (PTEN)
   04151 PI3K-Akt signaling pathway
    112931976 (PTEN)
   04150 mTOR signaling pathway
    112931976 (PTEN)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    112931976 (PTEN)
  09143 Cell growth and death
   04115 p53 signaling pathway
    112931976 (PTEN)
   04218 Cellular senescence
    112931976 (PTEN)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    112931976 (PTEN)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    112931976 (PTEN)
   05206 MicroRNAs in cancer
    112931976 (PTEN)
   05230 Central carbon metabolism in cancer
    112931976 (PTEN)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    112931976 (PTEN)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    112931976 (PTEN)
   05214 Glioma
    112931976 (PTEN)
   05218 Melanoma
    112931976 (PTEN)
   05215 Prostate cancer
    112931976 (PTEN)
   05213 Endometrial cancer
    112931976 (PTEN)
   05224 Breast cancer
    112931976 (PTEN)
   05222 Small cell lung cancer
    112931976 (PTEN)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    112931976 (PTEN)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    112931976 (PTEN)
   05165 Human papillomavirus infection
    112931976 (PTEN)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    112931976 (PTEN)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:vvp01009]
    112931976 (PTEN)
Enzymes [BR:vvp01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     112931976 (PTEN)
    3.1.3.48  protein-tyrosine-phosphatase
     112931976 (PTEN)
    3.1.3.67  phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase
     112931976 (PTEN)
Protein phosphatases and associated proteins [BR:vvp01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   Phosphatase and Tensin homologs (PTEN)
    112931976 (PTEN)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: PTEN_C2 DSPc Y_phosphatase Y_phosphatase3 PTPlike_phytase DUF3256
Motif
Other DBs
NCBI-GeneID: 112931976
NCBI-ProteinID: XP_025870582
UniProt: A0A3Q7UBM7
LinkDB All DBs
Position
Unknown
AA seq 403 aa AA seqDB search
MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSK
HKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVA
AIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSY
LLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMY
FEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEI
DSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEAS
SSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHTQITKV
NT seq 1212 nt NT seq  +upstreamnt  +downstreamnt
atgacagccatcatcaaggagatcgtcagcagaaacaaaaggcgctaccaggaggatggg
ttcgacttggacttgacctatatttatcccaacattattgctatggggtttcctgcagaa
agacttgaaggcgtatacaggaacaatattgatgatgtagtaaggtttttggattcaaag
cataaaaaccattacaagatatacaatctgtgtgctgaaagacattatgataccgccaaa
tttaactgcagagttgcacagtatccttttgaagaccataatccaccacagctagaactt
atcaaacccttttgtgaagatcttgaccaatggctaagtgaagatgacaatcatgttgca
gcaattcactgtaaagctggaaagggacgaactggtgtaatgatttgtgcatatttatta
catcggggcaaatttttaaaggcacaagaggccctagatttctatggggaagtaaggacc
agagacaaaaagggagtaactattcccagtcagaggcgctatgtgtattattatagctac
ctgttaaagaatcatctggattatagaccagtggcactgttgtttcacaagatgatgttt
gaaactattccaatgttcagtggcggaacttgcaatcctcagtttgtggtctgccagcta
aaggtgaagatctattcctccaattcaggacccacacgacgggaagacaagttcatgtac
tttgagttccctcagccgttgcctgtgtgcggtgacatcaaagtagagttcttccacaaa
cagaacaagatgctaaaaaaggacaaaatgtttcacttttgggtaaacacattcttcata
ccaggaccagaggaaacctcagaaaaagtagaaaatggaagtctatgtgatcaagaaatt
gatagtatttgcagtatagaacgtgcagataatgacaaggaatatctagtactcacttta
acaaaaaatgatctcgacaaagcaaataaagacaaggccaaccgatatttttctccaaat
tttaaggtgaagctgtacttcacaaaaaccgtagaggagccatcaaacccggaggctagc
agttcaacttctgtgacgccagatgttagtgacaatgaacctgatcattatagatattct
gacaccactgactctgacccagagaacgaaccctttgatgaagatcagcacacacaaatc
acaaaagtctga

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