Vulpes vulpes (red fox): 112931976
Entry
112931976 CDS
T05911
Gene name
PTEN
Definition
(RefSeq) phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1
KO
K01110
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:
3.1.3.16
3.1.3.48
3.1.3.67
]
Organism
vvp
Vulpes vulpes (red fox)
Pathway
vvp00562
Inositol phosphate metabolism
vvp01100
Metabolic pathways
vvp01521
EGFR tyrosine kinase inhibitor resistance
vvp04068
FoxO signaling pathway
vvp04070
Phosphatidylinositol signaling system
vvp04071
Sphingolipid signaling pathway
vvp04115
p53 signaling pathway
vvp04140
Autophagy - animal
vvp04150
mTOR signaling pathway
vvp04151
PI3K-Akt signaling pathway
vvp04218
Cellular senescence
vvp04510
Focal adhesion
vvp04931
Insulin resistance
vvp05165
Human papillomavirus infection
vvp05166
Human T-cell leukemia virus 1 infection
vvp05200
Pathways in cancer
vvp05206
MicroRNAs in cancer
vvp05213
Endometrial cancer
vvp05214
Glioma
vvp05215
Prostate cancer
vvp05218
Melanoma
vvp05222
Small cell lung cancer
vvp05224
Breast cancer
vvp05225
Hepatocellular carcinoma
vvp05230
Central carbon metabolism in cancer
vvp05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
vvp00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
112931976 (PTEN)
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
112931976 (PTEN)
04070 Phosphatidylinositol signaling system
112931976 (PTEN)
04071 Sphingolipid signaling pathway
112931976 (PTEN)
04151 PI3K-Akt signaling pathway
112931976 (PTEN)
04150 mTOR signaling pathway
112931976 (PTEN)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
112931976 (PTEN)
09143 Cell growth and death
04115 p53 signaling pathway
112931976 (PTEN)
04218 Cellular senescence
112931976 (PTEN)
09144 Cellular community - eukaryotes
04510 Focal adhesion
112931976 (PTEN)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
112931976 (PTEN)
05206 MicroRNAs in cancer
112931976 (PTEN)
05230 Central carbon metabolism in cancer
112931976 (PTEN)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
112931976 (PTEN)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
112931976 (PTEN)
05214 Glioma
112931976 (PTEN)
05218 Melanoma
112931976 (PTEN)
05215 Prostate cancer
112931976 (PTEN)
05213 Endometrial cancer
112931976 (PTEN)
05224 Breast cancer
112931976 (PTEN)
05222 Small cell lung cancer
112931976 (PTEN)
09167 Endocrine and metabolic disease
04931 Insulin resistance
112931976 (PTEN)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
112931976 (PTEN)
05165 Human papillomavirus infection
112931976 (PTEN)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
112931976 (PTEN)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
vvp01009
]
112931976 (PTEN)
Enzymes [BR:
vvp01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.16 protein-serine/threonine phosphatase
112931976 (PTEN)
3.1.3.48 protein-tyrosine-phosphatase
112931976 (PTEN)
3.1.3.67 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase
112931976 (PTEN)
Protein phosphatases and associated proteins [BR:
vvp01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Dual specificity phosphatases)
Phosphatase and Tensin homologs (PTEN)
112931976 (PTEN)
SSDB
Motif
Pfam:
PTEN_C2
DSPc
Y_phosphatase
Y_phosphatase3
PTPlike_phytase
DUF3256
Other DBs
NCBI-GeneID:
112931976
NCBI-ProteinID:
XP_025870582
UniProt:
A0A3Q7UBM7
LinkDB
Position
Unknown
AA seq
403 aa
MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSK
HKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVA
AIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSY
LLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMY
FEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEI
DSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEAS
SSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHTQITKV
NT seq
1212 nt
+upstream
nt +downstream
nt
atgacagccatcatcaaggagatcgtcagcagaaacaaaaggcgctaccaggaggatggg
ttcgacttggacttgacctatatttatcccaacattattgctatggggtttcctgcagaa
agacttgaaggcgtatacaggaacaatattgatgatgtagtaaggtttttggattcaaag
cataaaaaccattacaagatatacaatctgtgtgctgaaagacattatgataccgccaaa
tttaactgcagagttgcacagtatccttttgaagaccataatccaccacagctagaactt
atcaaacccttttgtgaagatcttgaccaatggctaagtgaagatgacaatcatgttgca
gcaattcactgtaaagctggaaagggacgaactggtgtaatgatttgtgcatatttatta
catcggggcaaatttttaaaggcacaagaggccctagatttctatggggaagtaaggacc
agagacaaaaagggagtaactattcccagtcagaggcgctatgtgtattattatagctac
ctgttaaagaatcatctggattatagaccagtggcactgttgtttcacaagatgatgttt
gaaactattccaatgttcagtggcggaacttgcaatcctcagtttgtggtctgccagcta
aaggtgaagatctattcctccaattcaggacccacacgacgggaagacaagttcatgtac
tttgagttccctcagccgttgcctgtgtgcggtgacatcaaagtagagttcttccacaaa
cagaacaagatgctaaaaaaggacaaaatgtttcacttttgggtaaacacattcttcata
ccaggaccagaggaaacctcagaaaaagtagaaaatggaagtctatgtgatcaagaaatt
gatagtatttgcagtatagaacgtgcagataatgacaaggaatatctagtactcacttta
acaaaaaatgatctcgacaaagcaaataaagacaaggccaaccgatatttttctccaaat
tttaaggtgaagctgtacttcacaaaaaccgtagaggagccatcaaacccggaggctagc
agttcaacttctgtgacgccagatgttagtgacaatgaacctgatcattatagatattct
gacaccactgactctgacccagagaacgaaccctttgatgaagatcagcacacacaaatc
acaaaagtctga
DBGET
integrated database retrieval system
