KEGG   Vulpes vulpes (red fox): 112933353
Entry
112933353         CDS       T05911                                 

Gene name
PDGFRA
Definition
(RefSeq) platelet-derived growth factor receptor alpha isoform X1
  KO
K04363  platelet-derived growth factor receptor alpha [EC:2.7.10.1]
Organism
vvp  Vulpes vulpes (red fox)
Pathway
vvp01521  EGFR tyrosine kinase inhibitor resistance
vvp04010  MAPK signaling pathway
vvp04014  Ras signaling pathway
vvp04015  Rap1 signaling pathway
vvp04020  Calcium signaling pathway
vvp04072  Phospholipase D signaling pathway
vvp04144  Endocytosis
vvp04151  PI3K-Akt signaling pathway
vvp04510  Focal adhesion
vvp04540  Gap junction
vvp04630  JAK-STAT signaling pathway
vvp04810  Regulation of actin cytoskeleton
vvp05163  Human cytomegalovirus infection
vvp05200  Pathways in cancer
vvp05206  MicroRNAs in cancer
vvp05214  Glioma
vvp05215  Prostate cancer
vvp05218  Melanoma
vvp05230  Central carbon metabolism in cancer
vvp05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:vvp00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    112933353 (PDGFRA)
   04014 Ras signaling pathway
    112933353 (PDGFRA)
   04015 Rap1 signaling pathway
    112933353 (PDGFRA)
   04630 JAK-STAT signaling pathway
    112933353 (PDGFRA)
   04020 Calcium signaling pathway
    112933353 (PDGFRA)
   04072 Phospholipase D signaling pathway
    112933353 (PDGFRA)
   04151 PI3K-Akt signaling pathway
    112933353 (PDGFRA)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    112933353 (PDGFRA)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    112933353 (PDGFRA)
   04540 Gap junction
    112933353 (PDGFRA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    112933353 (PDGFRA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    112933353 (PDGFRA)
   05206 MicroRNAs in cancer
    112933353 (PDGFRA)
   05230 Central carbon metabolism in cancer
    112933353 (PDGFRA)
   05231 Choline metabolism in cancer
    112933353 (PDGFRA)
  09162 Cancer: specific types
   05214 Glioma
    112933353 (PDGFRA)
   05218 Melanoma
    112933353 (PDGFRA)
   05215 Prostate cancer
    112933353 (PDGFRA)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    112933353 (PDGFRA)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    112933353 (PDGFRA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:vvp01001]
    112933353 (PDGFRA)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:vvp04090]
    112933353 (PDGFRA)
Enzymes [BR:vvp01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     112933353 (PDGFRA)
Protein kinases [BR:vvp01001]
 Receptor tyrosine kinases (RTK)
  PDGFR family [OT]
   112933353 (PDGFRA)
CD molecules [BR:vvp04090]
 Proteins
  112933353 (PDGFRA)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase Ig_3 I-set ig Ig_2 V-set Herpes_gE C2-set_2 Kinase-like
Other DBs
NCBI-GeneID: 112933353
NCBI-ProteinID: XP_025872296
UniProt: A0A3Q7U351
LinkDB
Position
Unknown
AA seq 1111 aa
MDERQFWGGSQSLLGDRKFSGTMGTSLLALLILGCLLAGPSLILCQLSLPSILPNENEKV
VQLNSSFSLRCFGESEVSWHYPTSEEENPNVEIRNEENNSGLFVTVLEVVNASAAHTGLY
TCYYNHTQTDENEIEGRHIYIYVPDPDVAFVPLGMTDYLVIVEDDDSAIIPCRTTDPETP
VTLLSSDGVVHASYDSRQGFNGTFSVGPYICEATVRGKKFQTIPFNVYALKATSELDLEM
EALKTVYKSGETIVVTCAVFNNEVVDLQWTYPGEVKGKGITMLEEIKVPSIKLVYTLTVP
EATVKDSGDYECAARQATKEVKEMKKVTISVHEKGFIEIKPNFSQLEAVDLHEVKHFVVD
VQAYPPPRISWLKDNLTLIENLTEITTDIERTQEIRYRSKLKLIRAKEEDSGHYTIVVQN
EDDVKSYTFELLTQVPSSILDLVDDHHGSTGGQTVRCIAEGTPLPDIEWMICKDIKKCNN
ETSWAILANNISNIITEVHPRDRNTVEGRVTFTRVEETIAVRCLAKNLLGAESRELKLVA
PTLRSELTVAAAVLVLLVIVIISLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPM
QLPYDSRWEFPRDGLVLGRILGSGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEK
QALMSELKIMTHLGPHLNIVNLLGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFLSRHP
EKPKKELDIFGLNPADDSTRSYVILSFENNGDYMDMKQADTTQYVPMLERKEVSKYSDIQ
RSLYDRPASYKKKSMLDSEVKNLLSDDNSEGLTLLDLLSFTYQVARGMEFLASKNCVHRD
LAARNVLLAQGKIVKICDFGLARDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDV
WSYGILLWEIFSLGGTPYPGMMVDSTFYNKIKSGYRMAKPDHATSEVYEIMVKCWHSEPE
KRPSFYHLSEIVENLLPGQYKKSYEKIHLDFLKSDHPAVARMHVDSDNAYIGVTYKNEED
KLKDWEGSLDEQRLSADSGYIIPLPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSSSST
FIKREDETIEDIDMMDDIGIDSSDLVEDSFL
NT seq 3336 nt   +upstreamnt  +downstreamnt
atggacgagcggcagttctgggggggaagccaaagcctgctcggggaccgaaagttttcc
ggaactatggggacttcccttctggcactcctgatcttaggctgtctcctcgcagggccc
agcctaatcctctgccagctttcattaccctcgatccttccaaatgaaaatgaaaaggtt
gtgcagctgaattcatccttttctctgagatgctttggggagagtgaagtgagttggcat
taccccacgtctgaagaagagaaccccaatgtggagatcagaaatgaggagaacaacagt
ggcctttttgtgaccgtgctggaagtggtcaatgcgtcggcggcgcacacggggctgtac
acttgctattacaaccacactcagacagacgaaaacgagatcgaaggcaggcacatctac
atctatgtgccagacccggatgtcgccttcgtacctctaggaatgacagattatttagtc
atcgtggaggatgatgactctgccatcataccttgtcgcacaactgatcccgagactccg
gtcaccttactcagcagtgacggggtggtacatgcgtcctatgacagcagacagggcttt
aatgggaccttcagcgttgggccgtatatctgtgaagccaccgtcaggggcaagaagttc
cagaccatcccatttaatgtttatgctttaaaagcaacgtcagaacttgatctagaaatg
gaagctcttaaaactgtgtataagtcaggggagacgattgtggtcacctgcgccgtcttt
aacaacgaggtggtggaccttcaatggacctaccctggagaggtgaaaggcaaaggcatc
accatgttggaggaaataaaggtcccgtccatcaaattggtgtacactctgacggtcccc
gaggccacggtgaaagatagtggagattatgaatgtgctgcccgccaggccaccaaggag
gtcaaagagatgaagaaagtcaccatttctgtccatgagaaagggttcattgaaatcaaa
cccaacttcagccagttggaagctgttgacctacacgaagtcaaacattttgtggtggac
gtgcaggcctacccacctcccaggatatcctggctgaaggacaacctgactctgattgaa
aatctcacggagatcaccactgacatagaaaggactcaggaaataaggtatcgaagcaaa
ttaaagctgatccgtgctaaggaggaggacagtggccattacactatcgtcgttcaaaat
gaggatgacgtcaagagctatactttcgaactcttaactcaagttccctcgtctattctg
gacttggtcgatgaccaccacggctctactgggggacagaccgtgagatgcatcgctgaa
gggacacctcttcctgatatcgagtggatgatttgcaaggatattaagaaatgtaataat
gaaacctcctgggcgattttggccaacaatatctcaaacattatcacggaggttcacccc
cgagacaggaatactgtggagggccgggtgaccttcaccagagtggaggagaccatcgcc
gttcgatgtctggccaagaatctccttggggccgagagccgagagctgaagctggtggct
cccacgctgcgttctgaactcacggtggcagctgcagtcctggtgctattggtgattgtg
atcatctcacttatcgtcctggttgtcatttggaaacagaaaccgaggtatgaaattcgt
tggagggtcattgaatccatcagccctgatggacatgaatatatttacgtggacccgatg
cagctgccttatgactcaagatgggagtttccaagagatggacttgtgcttggtcggatc
ctgggatctggtgcatttgggaaagtggttgaaggaactgcctatggattaagccgctcc
cagccggtcatgaaagtcgccgtgaagatgctgaaacccacagccagatccagtgaaaaa
caagctctcatgtcggaactgaagataatgactcacctggggccgcatttaaacattgtg
aacttgctgggagcctgtaccaagtcaggccccatttacatcatcaccgagtactgcttc
tatggggatttggtcaactatttgcataagaatagggatagcttcctgagccgccacccg
gagaagccaaagaaagagttggacatttttggattgaaccctgctgatgacagcacacgg
agttacgttattttatcttttgaaaacaacggtgactacatggacatgaagcaagctgac
accacacagtatgtccccatgctggaaaggaaagaggtttctaagtactcggacatccag
agatcgctgtatgatcgtccagcctcgtacaagaagaaatctatgttagactccgaagtc
aaaaacctcctttcggatgataactcagaaggccttactttgttggatttgttgagcttc
acctatcaagtcgcgcgaggaatggagtttttggcttcgaaaaattgtgtccaccgggac
ctggctgctcgaaacgtcctcctggcacaagggaaaatcgtgaagatctgtgacttcggc
ctggccagagacatcatgcacgattcaaactatgtgtctaaaggcagtacctttctcccc
gtgaagtggatggctcccgagagcatcttcgacaacctctacaccacgctgagtgacgtc
tggtcctacggcattctgctctgggagatcttttcccttggcggcacaccctaccctggc
atgatggtggattctactttctacaataagatcaagagtggataccggatggccaagcct
gaccatgccaccagtgaagtctatgagatcatggtgaagtgctggcacagtgagccggag
aagagaccctccttttaccacctgagtgagatcgtggagaatctgctgcctggacaatat
aagaagagttacgagaagattcacctggacttcctgaagagcgaccaccccgccgtggcg
cgtatgcacgtggactcggacaacgcctacatcggcgtcacctacaaaaatgaggaggac
aagctgaaggactgggagggcagcctggatgagcagaggctgagcgccgacagcggctac
atcatccccctgcccgacatcgacccggtgcccgaggaggaagacctgggcaagaggaac
agacacagctcgcagacctcagaagaaagcgctatcgagacaggttccagcagctctacc
ttcatcaagagagaggacgaaaccatcgaggacatcgacatgatggatgacattggcata
gactcctcagacctggtagaggacagcttcctgtga

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