Xenopus laevis (African clawed frog): 108705492 Help Entry 108705492         CDS       T01010                                  Definition (RefSeq) cyclin-dependent kinase 4-like   KO K02089   cyclin-dependent kinase 4 [EC:2.7.11.22] Organism xla  Xenopus laevis (African clawed frog) Pathway xla04110   Cell cycle xla04115   p53 signaling pathway xla04218   Cellular senescence xla04530   Tight junction Brite KEGG Orthology (KO) [BR:xla00001]  09140 Cellular Processes   09143 Cell growth and death    04110 Cell cycle     108705492    04115 p53 signaling pathway     108705492    04218 Cellular senescence     108705492   09144 Cellular community - eukaryotes    04530 Tight junction     108705492  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:xla01001]     108705492 Enzymes [BR:xla01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.22  cyclin-dependent kinase      108705492 Protein kinases [BR:xla01001]  Serine/threonine kinases: CMGC group   CDK family    108705492 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr POT1PC Motif Other DBs NCBI-GeneID:  108705492 NCBI-ProteinID:  XP_018097862 LinkDB All DBs Position Un AA seq 87 aa AA seqDB search MLYRGFLRRIPVWNMAKEMNGQYEPVAEIGVGAYGTVYKARDLHSGKFVALKNVRVQTNE NGLPLSTVREVALLKRLEHFDHPNIVK NT seq 264 nt NT seq  +upstreamnt  +downstreamnt atgctctacagggggttcttgagaagaataccggtgtggaatatggctaaagaaatgaac gggcagtatgagcctgtcgcagagatcggcgtcggggcttatggcacggtatacaaggcc agggaccttcacagtggaaagttcgtggccctgaaaaatgtgcgggtgcaaaccaacgag aatgggctccccctctctactgtcagggaagtggctttattaaaacgcctggagcatttt gaccatccaaacattgtaaagtaa

Xenopus laevis (African clawed frog): 108718479 Help Entry 108718479         CDS       T01010                                  Definition (RefSeq) cyclin-dependent kinase 6-like   KO K02091   cyclin-dependent kinase 6 [EC:2.7.11.22] Organism xla  Xenopus laevis (African clawed frog) Pathway xla04110   Cell cycle xla04115   p53 signaling pathway xla04218   Cellular senescence Brite KEGG Orthology (KO) [BR:xla00001]  09140 Cellular Processes   09143 Cell growth and death    04110 Cell cycle     108718479    04115 p53 signaling pathway     108718479    04218 Cellular senescence     108718479  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:xla01001]     108718479 Enzymes [BR:xla01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.22  cyclin-dependent kinase      108718479 Protein kinases [BR:xla01001]  Serine/threonine kinases: CMGC group   CDK family    108718479 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr Motif Other DBs NCBI-GeneID:  108718479 NCBI-ProteinID:  XP_018122302 LinkDB All DBs Position 6L AA seq 292 aa AA seqDB search MMEKDSLADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIRE VAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPDPGVPNET IKVPLKSEYIYVYGSFSMIQPMVVTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKP LFRGNSDVDQLGKIFDVIGLPEEDEWPHDVAVPRDAFHVRQPVPIDNVVQDIDEQGKDLL IKCLTFTPANRISAFSALSHPYFHDLQRSKDSVDSHRPSGQKDEGSAGSNTA NT seq 879 nt NT seq  +upstreamnt  +downstreamnt atgatggagaaggacagtctggccgatcagcagtatgagtgcgtggctgagatcggggaa ggggcgtatggcaaggtgtttaaggcccgtgacttgaagaatggtggtcgcttcgtggca ttgaaacgagtgcgggtgcagaccggggaggagggcatgccgctctctaccatcagggaa gtggcagtgcttcgtcacctggagaccttcgagcatcccaatgtggtcaggttgtttgat gtatgtacagtttcacggacagacagagagacaaaacttacactggtgtttgaacatgtt gatcaagatttgaccacttacttggacaaagtaccagatcctggggttccaaatgaaact attaaggtacctttgaaaagtgaatatatttatgtgtatggctcatttagtatgattcaa ccgatggtggtcaccttgtggtacagagccccagaagtcttactccagtcaagttacgcc acgccagttgatctttggagtgttggctgtatatttgcagaaatgtttcggcgaaagcca ctttttcgtggaaattcagatgtagaccaactaggaaaaatctttgatgtgattggactc ccagaggaagacgagtggccccatgatgtggctgttccgagggacgccttccatgttaga caacctgtgcccattgataatgttgttcaagatatagatgagcaaggcaaggacttactt attaaatgcctgaccttcactccagccaaccgcatctctgcgttcagcgccctgtcccac ccttacttccatgatttacagagaagcaaagacagtgtagactctcacaggccaagcggc caaaaggatgaaggttctgctggaagcaacactgcttga

Xenopus laevis (African clawed frog): 108719900 Help Entry 108719900         CDS       T01010                                  Definition (RefSeq) cyclin-dependent kinase 6   KO K02091   cyclin-dependent kinase 6 [EC:2.7.11.22] Organism xla  Xenopus laevis (African clawed frog) Pathway xla04110   Cell cycle xla04115   p53 signaling pathway xla04218   Cellular senescence Brite KEGG Orthology (KO) [BR:xla00001]  09140 Cellular Processes   09143 Cell growth and death    04110 Cell cycle     108719900    04115 p53 signaling pathway     108719900    04218 Cellular senescence     108719900  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:xla01001]     108719900 Enzymes [BR:xla01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.22  cyclin-dependent kinase      108719900 Protein kinases [BR:xla01001]  Serine/threonine kinases: CMGC group   CDK family    108719900 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr APH Kdo RIO1 Kinase-like FTA2 Seadorna_VP7 Motif Other DBs NCBI-GeneID:  108719900 NCBI-ProteinID:  XP_018124671 UniProt:  A0A1L8FQZ7 LinkDB All DBs Position 6S AA seq 329 aa AA seqDB search MEKDSLADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPMSTIREV AVLRHLETFEHPNVVRLFDICTVSRTDRETKLTLVFEHVDQDLTTYLNKVPDPGVPNETI KDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSNGQIKLADFGLARIYSFQMALTSVVVT LWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGNSDVDQLGKIFDVIGLPKEDE WPHDVAVARDALHFKQPLPIENVVPDIDEQGKDLLIKCLTFTPANRISASGALSHPYFHD LQKYKDNVDSHRPSGQKGVDKVSAGNKTN NT seq 990 nt NT seq  +upstreamnt  +downstreamnt atggagaaggacagcctggccgatcagcagtacgagtgtgtggctgagataggggaaggg gcgtatggcaaggtgtttaaggcccgcgacttaaagaacggaggtcgttttgtggctctg aaacgagtgcgggtgcagaccggggaggagggcatgccgatgtctaccatccgggaagtg gcagtgcttcgtcatctggagaccttcgagcatcccaatgtggtcaggttgtttgatata tgtacagtttcacggacagacagagagacaaaacttacactggtgtttgaacatgttgat caagatttgaccacttacttgaataaagtaccagatcctggggtcccaaatgaaactatt aaggatatgatgttccagcttcttcgaggactggattttcttcattcccatagagtggtg catcgagacctaaagcctcaaaacattcttgtcaccagcaacggacagataaaactagca gacttcggccttgccagaatttacagttttcagatggcactcacatcagtggtggtcacc ttatggtacagagccccagaagtcttacttcagtcaagttacgccacgccagttgatctt tggagtgttggctgtatatttgcagaaatgtttcggcgaaagccactttttcgtggaaat tcagatgttgaccaattaggaaaaatctttgatgttattggactcccaaaggaagacgag tggccccatgatgtggctgttgcaagggacgccttgcattttaaacagcctctgcccatt gaaaatgttgttccagatatagatgagcaaggcaaggacttacttattaaatgcttaacc ttcactccagccaaccgcatctctgcatcaggcgctctgtcccacccttatttccacgat ttacagaaatacaaagacaatgtagactctcacaggccaagcggccaaaagggggtggat aaagtttctgctggaaacaagaccaattga

Xenopus laevis (African clawed frog): 379406 Help Entry 379406            CDS       T01010                                  Gene name cdk4.L, cdk4, xcdk4 Definition (RefSeq) cyclin-dependent kinase 4 L homeolog   KO K02089   cyclin-dependent kinase 4 [EC:2.7.11.22] Organism xla  Xenopus laevis (African clawed frog) Pathway xla04110   Cell cycle xla04115   p53 signaling pathway xla04218   Cellular senescence xla04530   Tight junction Brite KEGG Orthology (KO) [BR:xla00001]  09140 Cellular Processes   09143 Cell growth and death    04110 Cell cycle     379406 (cdk4.L)    04115 p53 signaling pathway     379406 (cdk4.L)    04218 Cellular senescence     379406 (cdk4.L)   09144 Cellular community - eukaryotes    04530 Tight junction     379406 (cdk4.L)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:xla01001]     379406 (cdk4.L) Enzymes [BR:xla01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.22  cyclin-dependent kinase      379406 (cdk4.L) Protein kinases [BR:xla01001]  Serine/threonine kinases: CMGC group   CDK family    379406 (cdk4.L) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr APH Kdo POT1PC Motif Other DBs NCBI-GeneID:  379406 NCBI-ProteinID:  NP_001079719 Xenbase:  XB-GENE-5900736 UniProt:  Q91727 LinkDB All DBs Position 2S AA seq 319 aa AA seqDB search MSKEMKGQYEPVAEIGVGAYGTVYKARDLQSGKFVALKNVRVQTNENGLPLSTVREVTLL KRLEHFDHPNIVKLMDVCASARTDRETKVTLVFEHVDQDLKTYLSKVPPPGLPLETIKDL MKQFLSGLEFLHLNCIVHRDLKPENILVTSGGQVKLADFGLARIYSCQMALTPVVVTLWY RAPEVLLQSTYATPVDVWSAGCIFAEMFKRKPLFCGNSEADQLCKIFDIIGLPSEEEWPV DVTLPRSAFSPRTQQPVDKFVPEIDAMGADLLLAMLTFSPQKRISASDALLHPFFADDPQ ACSKQEHFTHICTATDEVK NT seq 960 nt NT seq  +upstreamnt  +downstreamnt atgtcaaaagaaatgaagggtcaatatgaacctgtcgcagagattggcgtcggggcttac ggcacggtatacaaggccagggaccttcaaagtggaaagtttgttgccctcaaaaatgtg cgggtgcaaaccaacgagaatggactccccctctctacggtcagggaagtgactttattg aaacgcctggagcattttgaccatccaaacattgtaaaacttatggatgtttgtgcttct gcccgaactgaccgagagactaaagtgacgctggtgtttgaacatgtggaccaagacctg aagacttacttgagcaaagtcccacctccaggtcttccactggagactattaaggacctc atgaagcagttcctttcgggcctggaattcctccatttgaattgcattgtgcaccgagac cttaaaccggagaatatcttggtgacaagtgggggacaggtgaaacttgccgactttggc ctagcgaggatatacagctgtcagatggctctcacgcccgtggtggtgacgttgtggtac agggccccagaagtcctgcttcagtccacgtatgccacgccggtagatgtgtggagcgcg ggctgcatcttcgcagagatgttcaagcgaaaacccctgttctgcggcaattcagaagct gaccagttgtgcaagatatttgatattattgggcttccttctgaagaggagtggccggtg gatgttactttgccacgttctgccttttccccgaggactcagcagccagtggacaagttt gtgccggaaatcgatgccatgggagccgatcttcttctggccatgctgaccttcagccct caaaaacgtatttccgcctccgatgctctgctccacccctttttcgctgacgatccccag gcctgctccaaacaagaacactttactcatatctgcaccgcaacggatgaagtgaaatga

Xenopus laevis (African clawed frog): 496334 Help Entry 496334            CDS       T01010                                  Gene name cdk6.L, cdk6, plstire Definition (RefSeq) cyclin-dependent kinase 6 L homeolog   KO K02089   cyclin-dependent kinase 4 [EC:2.7.11.22] Organism xla  Xenopus laevis (African clawed frog) Pathway xla04110   Cell cycle xla04115   p53 signaling pathway xla04218   Cellular senescence xla04530   Tight junction Brite KEGG Orthology (KO) [BR:xla00001]  09140 Cellular Processes   09143 Cell growth and death    04110 Cell cycle     496334 (cdk6.L)    04115 p53 signaling pathway     496334 (cdk6.L)    04218 Cellular senescence     496334 (cdk6.L)   09144 Cellular community - eukaryotes    04530 Tight junction     496334 (cdk6.L)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:xla01001]     496334 (cdk6.L) Enzymes [BR:xla01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.22  cyclin-dependent kinase      496334 (cdk6.L) Protein kinases [BR:xla01001]  Serine/threonine kinases: CMGC group   CDK family    496334 (cdk6.L) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr APH Kdo POT1PC Motif Other DBs NCBI-GeneID:  496334 NCBI-ProteinID:  NP_001088955 Xenbase:  XB-GENE-6252089 UniProt:  Q5HZQ2 LinkDB All DBs Position Un AA seq 319 aa AA seqDB search MAKEMNGQYEPVAEIGVGAYGTVYKARDLHSGKFVALKNVRVQTNENGLPLSTVREVALL KRLEHFDHPNIVKLMDVCASVRTDRETKVTLVFEHVDQDLKTYLSKVPPPGLPLETIKDL MKQFLQGLEFLHLNCIVHRDLKPENILVTSGGQVKLADFGLARIYSCHMALTPVVVTLWY RAPEVLLQSTYATPVDMWSAGCIFSEMFKQKPLFCGNSEADQLCKIFEMIGLPSEEEWPA DVTLSRSAFSPRTQQPVEKFVPEIDPNGADLLLAMLTFSPQKRVSASDALLHPFFAEDPQ ACSKQEHFTSIRPMTDDVK NT seq 960 nt NT seq  +upstreamnt  +downstreamnt atggctaaagaaatgaacgggcagtatgagcctgtcgcagagatcggcgtcggggcttat ggcacggtatacaaggccagggaccttcacagtggaaagttcgtggccctgaaaaatgtg cgggtgcaaaccaacgagaatgggctccccctctctactgtcagggaagtggctttatta aaacgcctggagcattttgaccatccaaacattgtaaaactcatggacgtctgtgcttct gtccgaaccgaccgtgagactaaagtgacgctggtgtttgagcatgtggaccaagacctg aagacttacttgagcaaagtcccacctccaggtcttccactggagactattaaggacctc atgaagcagttccttcaaggactggaattcctccatttgaattgcattgtgcatcgagat cttaaacccgagaacatcttggtgacaagtgggggacaggtgaaactcgccgacttcggc ctagcgaggatatacagctgtcacatggctctcacgcccgtggtagtgacgttgtggtac agagccccagaagtcctgcttcagtccacgtatgccacgccggtagatatgtggagcgcg ggctgcatcttctcagagatgttcaagcaaaaacccctgttctgcggcaattcagaagct gaccagttgtgcaagatatttgaaatgattgggcttccttctgaagaagagtggccagcg gatgttactttgtctcgttctgccttttccccgaggactcagcagccagtggagaagttt gtgccggaaattgatcccaatggagctgatcttctgctggccatgttgaccttcagccct caaaaacgtgtctccgcctctgacgctctgctccaccccttttttgcggaggatccccag gcctgctccaaacaagaacactttacttctatccgccccatgacggatgatgtgaaatga

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