Xenopus laevis (African clawed frog): 108712802
Help
Entry
108712802 CDS
T01010
Gene name
map2k1.S, mek1
Definition
(RefSeq) mitogen-activated protein kinase kinase 1 S homeolog
KO
K04368
mitogen-activated protein kinase kinase 1 [EC:
2.7.12.2
]
Organism
xla
Xenopus laevis (African clawed frog)
Pathway
xla04010
MAPK signaling pathway
xla04012
ErbB signaling pathway
xla04068
FoxO signaling pathway
xla04114
Oocyte meiosis
xla04140
Autophagy - animal
xla04150
mTOR signaling pathway
xla04210
Apoptosis
xla04218
Cellular senescence
xla04270
Vascular smooth muscle contraction
xla04370
VEGF signaling pathway
xla04371
Apelin signaling pathway
xla04510
Focal adhesion
xla04540
Gap junction
xla04620
Toll-like receptor signaling pathway
xla04810
Regulation of actin cytoskeleton
xla04910
Insulin signaling pathway
xla04912
GnRH signaling pathway
xla04914
Progesterone-mediated oocyte maturation
xla04916
Melanogenesis
xla05132
Salmonella infection
Brite
KEGG Orthology (KO) [BR:
xla00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
108712802 (map2k1.S)
04012 ErbB signaling pathway
108712802 (map2k1.S)
04370 VEGF signaling pathway
108712802 (map2k1.S)
04371 Apelin signaling pathway
108712802 (map2k1.S)
04068 FoxO signaling pathway
108712802 (map2k1.S)
04150 mTOR signaling pathway
108712802 (map2k1.S)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
108712802 (map2k1.S)
09143 Cell growth and death
04114 Oocyte meiosis
108712802 (map2k1.S)
04210 Apoptosis
108712802 (map2k1.S)
04218 Cellular senescence
108712802 (map2k1.S)
09144 Cellular community - eukaryotes
04510 Focal adhesion
108712802 (map2k1.S)
04540 Gap junction
108712802 (map2k1.S)
09142 Cell motility
04810 Regulation of actin cytoskeleton
108712802 (map2k1.S)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
108712802 (map2k1.S)
09152 Endocrine system
04910 Insulin signaling pathway
108712802 (map2k1.S)
04912 GnRH signaling pathway
108712802 (map2k1.S)
04914 Progesterone-mediated oocyte maturation
108712802 (map2k1.S)
04916 Melanogenesis
108712802 (map2k1.S)
09153 Circulatory system
04270 Vascular smooth muscle contraction
108712802 (map2k1.S)
09160 Human Diseases
09171 Infectious disease: bacterial
05132 Salmonella infection
108712802 (map2k1.S)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
xla01001
]
108712802 (map2k1.S)
Enzymes [BR:
xla01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.12 Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
2.7.12.2 mitogen-activated protein kinase kinase
108712802 (map2k1.S)
Protein kinases [BR:
xla01001
]
Serine/threonine kinases: STE group
STE7 family
108712802 (map2k1.S)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Pkinase_fungal
Seadorna_VP7
Kinase-like
DUF3216
Motif
Other DBs
NCBI-GeneID:
108712802
NCBI-ProteinID:
XP_018110734
Xenbase:
XB-GENE-17341792
UniProt:
A0A1L8GSC6
LinkDB
All DBs
Position
3S
AA seq
395 aa
AA seq
DB search
MPKKKPTPIQLNPNPEGTAVNGTPTAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKV
GELKDDDFEKVSELGAGNGGVVFKVSHKPTSLIMARKLIHLEIKPAIRNQIIRELQVLHE
CNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGKIPEKILGKVSIAVIKGLTYL
REKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHY
SVQSDIWSMGLSLVEMAIGRYPIPPPDAKELELIFGCSVEGDPASSELAPRPRPPGRPIS
SYGPDSRPPMAIFELLDYIVNEPPPKLPSGVFGAEFQEFVNKCLVKNPAERADLKQLMVH
SFIKQSELDEVDFAGWLCSTMGLKQPSTPTHAAGV
NT seq
1188 nt
NT seq
+upstream
nt +downstream
nt
atgcctaaaaagaagcctacgcccatacagctgaaccccaaccccgaagggactgctgtc
aacggaacccctacagccgagacaaaccttgaagctctgcagaaaaagctagaggagctt
gagctggatgagcagcagaggaagcgtctggaggcttttctcacccagaagcagaaagtt
ggagaactgaaggatgacgactttgagaaagtttcggagcttggagcaggcaatggagga
gtggtgtttaaggtgtcccacaagccgaccagcttgattatggctagaaagttaattcat
ctggagattaagcctgcaatccgaaaccagattatccgagagttgcaggttctgcatgag
tgtaactccccatacattgtgggcttctatggggccttctacagtgatggagagatcagc
atttgcatggaacacatggatggaggctcccttgatcaggttttgaagaaagctggcaaa
atcccagagaagatattgggaaaagtcagcattgccgtgataaaaggtttaacctacctg
agagagaagcataagataatgcacagagatgtgaaaccttctaacatcctggtcaactct
agaggagagataaaactgtgcgactttggggtcagcgggcagctcatagattccatggca
aattcctttgttgggacaagatcctatatgtcgccagagaggctacagggcactcattac
tctgtgcaatccgacatctggagcatggggctgtcactggtggaaatggccattggaagg
tatcccattccaccgcctgatgccaaagagctggaacttatctttggctgttctgtagaa
ggggacccggcatcttctgaactggcacctcgcccccggccacccggacgtccaataagt
tcatatggtcctgatagtcgaccacccatggccattttcgaacttctggattatatagtg
aacgagccacctccaaaattgcccagtggagtatttggagcggagttccaggagtttgtg
aacaaatgtcttgtgaagaatccggctgagagagcagaccttaaacagctaatggttcac
agctttattaagcagtcagagttggatgaggtggattttgctggatggctctgttccact
atgggccttaagcagcccagtaccccaacccatgccgcaggagtgtga
Xenopus laevis (African clawed frog): 379991
Help
Entry
379991 CDS
T01010
Gene name
map2k1.L, map2k1, mek-2
Definition
(RefSeq) mitogen-activated protein kinase kinase 1 L homeolog
KO
K04368
mitogen-activated protein kinase kinase 1 [EC:
2.7.12.2
]
Organism
xla
Xenopus laevis (African clawed frog)
Pathway
xla04010
MAPK signaling pathway
xla04012
ErbB signaling pathway
xla04068
FoxO signaling pathway
xla04114
Oocyte meiosis
xla04140
Autophagy - animal
xla04150
mTOR signaling pathway
xla04210
Apoptosis
xla04218
Cellular senescence
xla04270
Vascular smooth muscle contraction
xla04370
VEGF signaling pathway
xla04371
Apelin signaling pathway
xla04510
Focal adhesion
xla04540
Gap junction
xla04620
Toll-like receptor signaling pathway
xla04810
Regulation of actin cytoskeleton
xla04910
Insulin signaling pathway
xla04912
GnRH signaling pathway
xla04914
Progesterone-mediated oocyte maturation
xla04916
Melanogenesis
xla05132
Salmonella infection
Brite
KEGG Orthology (KO) [BR:
xla00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
379991 (map2k1.L)
04012 ErbB signaling pathway
379991 (map2k1.L)
04370 VEGF signaling pathway
379991 (map2k1.L)
04371 Apelin signaling pathway
379991 (map2k1.L)
04068 FoxO signaling pathway
379991 (map2k1.L)
04150 mTOR signaling pathway
379991 (map2k1.L)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
379991 (map2k1.L)
09143 Cell growth and death
04114 Oocyte meiosis
379991 (map2k1.L)
04210 Apoptosis
379991 (map2k1.L)
04218 Cellular senescence
379991 (map2k1.L)
09144 Cellular community - eukaryotes
04510 Focal adhesion
379991 (map2k1.L)
04540 Gap junction
379991 (map2k1.L)
09142 Cell motility
04810 Regulation of actin cytoskeleton
379991 (map2k1.L)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
379991 (map2k1.L)
09152 Endocrine system
04910 Insulin signaling pathway
379991 (map2k1.L)
04912 GnRH signaling pathway
379991 (map2k1.L)
04914 Progesterone-mediated oocyte maturation
379991 (map2k1.L)
04916 Melanogenesis
379991 (map2k1.L)
09153 Circulatory system
04270 Vascular smooth muscle contraction
379991 (map2k1.L)
09160 Human Diseases
09171 Infectious disease: bacterial
05132 Salmonella infection
379991 (map2k1.L)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
xla01001
]
379991 (map2k1.L)
Enzymes [BR:
xla01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.12 Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
2.7.12.2 mitogen-activated protein kinase kinase
379991 (map2k1.L)
Protein kinases [BR:
xla01001
]
Serine/threonine kinases: STE group
STE7 family
379991 (map2k1.L)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Pkinase_fungal
Seadorna_VP7
Kinase-like
DUF3216
Motif
Other DBs
NCBI-GeneID:
379991
NCBI-ProteinID:
NP_001080299
Xenbase:
XB-GENE-865216
UniProt:
Q05116
A0A1L8H157
LinkDB
All DBs
Position
3L
AA seq
395 aa
AA seq
DB search
MPKKKPTPIQLNPNPEGTAVNGTPTAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKV
GELKDDDFEKVSELGAGNGGVVFKVSHKPTSLIMARKLIHLEIKPAIRNQIIRELQVLHE
CNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGKIPEKILGKVSIAVIKGLTYL
REKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHY
SVQSDIWSMGLSLVEMAIGRYPIPPPDAKELELIFGCSVERDPASSELAPRPRPPGRPIS
SYGPDSRPPMAIFELLDYIVNEPPPKLPSGVFGAEFQDFVNKCLVKNPAERADLKQLMVH
SFIKQSELEEVDFAGWLCSTMGLKQPSTPTHAAGV
NT seq
1188 nt
NT seq
+upstream
nt +downstream
nt
atgcctaaaaagaagcctacgcccatacagctgaatcccaaccccgaagggactgctgtg
aacgggacccctacagccgagacaaaccttgaagctctgcagaaaaagttggaagagctt
gagctggatgagcagcagaggaagcgtctggaggcttttctcacccagaagcagaaagtt
ggggaactgaaggatgacgactttgaaaaagtttcagagcttggagcaggcaacggagga
gtggtgtttaaggtgtcccacaagccaaccagcttgattatggccaggaagttgattcat
ctggagattaagcctgcaatccgaaaccagattatccgagagttgcaggttctgcatgaa
tgtaactccccatacattgtggggttctatggggccttctacagtgatggagagatcagc
atttgcatggaacacatggatggaggctcccttgatcaggttctgaagaaagctggcaaa
atcccagaaaagattttgggaaaagtcagcattgcagtgataaaaggtctaacctacctg
agagaaaagcataagataatgcacagagatgtgaaaccttctaacatcctggtcaactct
agaggagagataaaactctgcgactttggggtcagcgggcaactcatagactccatggca
aattcctttgttgggacaagatcctatatgtcaccggagcgactacagggcactcattat
tctgtgcaatcagacatctggagcatggggctgtcgctggtggaaatggccattggaagg
tatcccattccaccccctgatgccaaagagctggaacttatctttgggtgttctgtagaa
agggatccagcatcttctgaactggcacctcgcccccggccacccggacgtccaataagc
tcatacggtcctgatagtcgaccacccatggctatttttgaacttctggattatatcgtg
aacgagccgcctccaaaattgcccagtggagtatttggagctgagttccaggactttgtg
aataaatgtcttgtgaagaatccggcagagagagcagaccttaaacagctaatggttcac
agcttcattaagcagtcagagttggaggaagtggattttgctggatggctctgttccact
atgggccttaagcagcccagtaccccaacccatgccgccggagtgtga
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