KEGG   ENZYME: 1.1.1.108
Entry
EC 1.1.1.108                Enzyme                                 
Name
carnitine 3-dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
carnitine:NAD+ 3-oxidoreductase
Reaction(IUBMB)
carnitine + NAD+ = 3-dehydrocarnitine + NADH + H+ [RN:R02395]
Reaction(KEGG)
R02395
Substrate
carnitine [CPD:C00487];
NAD+ [CPD:C00003]
Product
3-dehydrocarnitine [CPD:C02636];
NADH [CPD:C00004];
H+ [CPD:C00080]
History
EC 1.1.1.108 created 1972
Orthology
K17735  carnitine 3-dehydrogenase
Genes
SKSFCN78_04110
PAEPA5386(cdhA)
PAEVN297_5571
PAEIN296_5571
PAUPA14_71140
PAPPSPA7_6172
PAGPLES_57821
PAFPAM18_5506
PNCNCGM2_6160
PAEBNCGM1900_6238
PDKPADK2_28665
PSGG655_28330
PRPM062_28380
PAEPPA1S_29110
PAERPA1R_gp3320
PAEMU769_29610
PAELT223_29570
PAESSCV20265_6117
PAEUBN889_05979
PAEGAI22_04880
PAECM802_5569
PAEOM801_5436
PMYPmen_0501
PMKMDS_0539
PREPCA10_04190
PFUWKF707C_3770
PCQPcP3B5_28840(lcdH_1) PcP3B5_61770(lcdH_3)
PMUIG4G71_03080
PPUPP_0302(lcdH)
PPFPput_0322
PPGPputGB1_0326
PPWPputW619_4906
PPTPPS_0295
PPBPPUBIRD1_0331
PPIYSA_05609
PPXT1E_2549(cryL1)
PPUHB479_01940
PPUTL483_01535
PPUNPP4_03300
PPUDDW66_0306
PFVPsefu_4236
PMONX969_27695
PMOTX970_27310
PMOSO165_021495
PPJRK21_04724
PORAPT59_00675
PMOLCLJ08_11090
PSBPsyr_2918
PFLPFL_5754
PPRCPFLCHA0_c57070
PPROPPC_5700(fadB)
PFEPSF113_5456(cdhA)
PFNHZ99_15465
PFOPfl01_5232
PFSPFLU_5675
PFCPflA506_4971
PPZH045_18695
PFBVO64_0484 VO64_2559
PMANOU5_3945
PTVAA957_16675
PCGAXG94_13170
PVRPverR02_29115
PAZOAYR47_04530
POIBOP93_24130
PRXHRH33_24965
PFWPF1751_v1c50980
PFFPFLUOLIPICF710500
PFXA7318_25075
PENPSEEN5183
PSTTCH92_03720
PBAPSEBR_a5237
PBCCD58_27495
PPUUPputUW4_05035(hbd)
PDRH681_25115
PSVPVLB_23770
PSKU771_29375
PKCPKB_5777(lcdH)
PCHEY04_31850
PCZPCL1606_05070
PCPJM49_02645
PFZAV641_01790
PALKPSAKL28_03330
PRHLT40_17755
PSWLK03_04180
PPVNJ69_17060
PSEMTO66_29110
PSECCCOS191_0335(lcdH)
PPSYAOC04_21975
PSOSPOS17_5688(fadB)
PKRAYO71_28025
PFKPFAS1_13520
PANRA7J50_5400
PPSLBJP27_13685
PSETTHL1_364
PSILPMA3_28045
PYMAK972_0257
PKEDLD99_26670
PALLUYA_02285
PUMHGP31_28935
POJPtoMrB4_04660(lcdH)
PGGFX982_01204
PPSHG5J76_04755
PGYAWU82_08720
PLALFXN65_01995
PSEJHNQ25_22010
PVKEPZ47_27595
PEZHWQ56_26715
PBZGN234_20615
PKHJLK41_02385
PTYJWV26_13150
PMAOPMYSY11_3771(lcdH) PMYSY11_3918(lcdH)
PATAJWU58_02890
PDWBV82_1792
PZEHU754_027960
PMOEHV782_027000
PSEPC4K39_3912
PVWHU752_030295
PTRTHU722_0027365
PXAKSS93_00210
PSAMHU731_013475
PTZHU718_028195
PSHHHU773_025910
PXNHU772_001630
PHVHU739_020065
PPRGHU725_001465
PANHHU763_001400
PASGKSS96_26510
PFAKKSS94_01745
PMUYKSS95_01440
PMAMKSS90_01630
PAZEKSS91_26725
PALVKSS97_26900
PORYEJA05_01640
PTKEXN22_25765
PTWTUM18999_06260(lcdH)
PZAHU749_027690
PIEHU724_026105
PTAENCTC10697_00376(paaH)
PGFJ0G10_28545
MBSMRBBS_1827
ABBABBFA_02248(lcdH)
ABXABK1_1705
ABZABZJ_01412
ABRABTJ_02453
ABDABTW07_1433
ABHM3Q_1628
ABADABD1_12840
ABJBJAB07104_01422
ABABBJAB0715_01435
ABAJBJAB0868_01370
ABAZP795_11120
ABKLX00_06220
ABAUIX87_04195
ABAAIX88_08440
ABWBL01_13460
ABALABLAC_20940
ACCBDGL_000609(cryL1)
ALCOTEC02_12010
ACALBUM88_06605
ACDAOLE_12420
ACWA0J50_11000
AGUAS4_16040
ABERBSR55_05550
MCELLPW13_04085
NAXHC341_11735
GAIIMCC3135_12745(lcdH_1) IMCC3135_17730(lcdH_3)
CSACsal_3173
HELHELO_2748(lcdH)
HCSFF32_18085
HAKKO116_02882
HAMHALO3119
HHUAR456_09285
HSIBOX17_07490
HBEBEI_1570(lcdH)
HAGBB497_10025
HAFC8233_00655
HALKCUU95_07290 CUU95_12950
HVNEI420_12650 EI420_18960
HOLHORIV_23150
HSRHSBAA_22100
HAXIHAALTHF_16130n
HTTHZS52_20030
HPIZGYM47_15565
HAAA5892_12955
CMAIBFX80_07130
CAMHLCW13_10150
KUSB9G99_01585
KMAB9H00_13575
KUYFY550_11975
PAURFGL86_03175
APACS7S_14045
MPRIMP3633_3289
MARSA8C75_21920
NIKF5I99_00755
SALNSALB1_2554
TSNW908_00370
THINCRN91_01000
PSENH8B_0037
BMABMAA0492
BMVBMASAVP1_0689
BMLBMA10229_0985
BMNBMA10247_A1957
BMALDM55_2713 DM55_4075
BMAEDM78_2271 DM78_3551
BMAQDM76_2697 DM76_4772
BMAIDM57_13055 DM57_2810
BMAFDM51_2646 DM51_4217
BMAZBM44_2496 BM44_4035
BMABBM45_2061 BM45_4812
BPSBPSS0568
BPMBURPS1710b_A2130
BPLBURPS1106A_A0762
BPDBURPS668_A0852
BPSEBDL_3796 BDL_692
BPSMBBQ_2119 BBQ_5626
BPSUBBN_2245 BBN_3968
BPSDBBX_2633 BBX_5633
BPZBP1026B_I2214 BP1026B_II0628
BPQBPC006_I1522 BPC006_II0807
BPKBBK_196 BBK_3923
BPSHDR55_3274 DR55_4783
BPSABBU_5478 BBU_868
BPSOX996_2881 X996_3747
BUTX994_1340 X994_4051
BTEBTH_II1847
BTQBTQ_1212 BTQ_5131
BTJBTJ_1221 BTJ_3759
BTZBTL_2456 BTL_4617
BTDBTI_2506 BTI_5398
BTVBTHA_2642 BTHA_5612
BTHEBTN_2202 BTN_4256
BTHMBTRA_2813 BTRA_3837
BTHADR62_2437 DR62_4305
BTHLBG87_2704 BG87_4588
BOKDM82_4671 DM82_766
BOCBG90_251 BG90_5923
BUUWS70_11100 WS70_20325
BSAVWS86_12070 WS86_21515
BVIBcep1808_3392
BVEAK36_3369 AK36_4332
BURBcep18194_B0613 Bcep18194_C7698
BCNBcen_3317
BCHBcen2424_5050
BCMBcenmc03_5234
BCJBCAM2293
BCENDM39_1142 DM39_5571
BCEWDM40_4993
BCEOI35_6184
BAMBamb_4458
BACBamMC406_4978
BMUBmul_3590
BMKDM80_4975
BMULNP80_4950
BCTGEM_3397
BCEDDM42_5698
BCEPAPZ15_27650
BDLAK34_3506
BPYRABD05_24120
BCONNL30_01095
BUBBW23_3456 BW23_475
BDFWI26_24150
BLATWK25_27445
BTEIWS51_08485
BSEMWJ12_31355
BPSLWS57_02755 WS57_24040
BMECWJ16_29805
BSTGWT74_30180
BSTLBBJ41_25215
BANNJFN94_29305
BGLbglu_2g06130
BGUKS03_5304
BUGBC1001_4157
BGFBC1003_5259
BGDbgla_2g08790
BGOBM43_4491
BYIBYI23_B012410
BUKMYA_3010
BUEBRPE67_BCDS16180(lcdH) BRPE67_DCDS03790
BULBW21_2522 BW21_5079
BUQAC233_28745
BGPBGL_2c07850(hbd1)
BPLAbpln_2g08720
BUDAQ610_11940 AQ610_27810
BUMAXG89_19840
BUIAX768_29605
BURKDM992_22890
BXEBxe_B0826
BXBDR64_6149 DR64_7527
BPHBphy_3284
BPXBUPH_00739
BPYBphyt_4508
BFNOI25_6578
BCAIK788_0002736
PARBCJU94_25140
PHSC2L64_26855 C2L64_44910
PTERC2L65_21510 C2L65_27715
PGPCUJ91_27470
PCJCUJ87_17610
PTSCUJ90_20665
PCAFDSC91_000805
PMEGFNZ07_10555
PACSFAZ98_16240
PDIOPDMSB3_2564.1(lcdH)
PPKU875_11020
PPNODA70_03430
PPNMLV28_02895
PRBX636_23680
PPULRO07_21760
PSPUNA29_15330
PAPISG18_20725
PVEUC34_13100
POXMB84_17625
PFGAB870_00170
PNRAT302_19055
PANDDRB87_12090
PFIBPI93_014865
PLGNCTC10937_02583(paaH)
CABASBC2_55400(lcdH_2)
BUOBRPE64_BCDS13590
BPETB1917_1816
BPEUQ425_30110
BBXBBS798_3215
BHOD560_0587
BHMD558_0577
BTRMSAMEA390648704204(fadB2_2)
BGMCAL15_12125
AXNAX27061_4678
AXXERS451415_04708(paaH_5)
ADTAPT56_21550
AISBUW96_13125
ASWCVS48_26040
ACHRC2U31_15905
ACHBDVB37_20155
PUDG9Q38_10255
AMIMMIM_c27310
CDNBN940_17536
PACRFXN63_04545
VEIVeis_3967
VBOCKY39_00430
VAMC4F17_18655
HSZACP92_22610
HHFE2K99_23830
HFRG5S34_23775
CARELT85_3173
DDZDSYM_02090
DRTDret_0345
MLOmlr5041
MLNA9174_02200
MCIMesci_0424
MOPMesop_0442
MAMMesau_00644
MAMOA6B35_06065
MESWA9K65_002130 A9K65_030975 A9K65_031125
MESMEJ066_09380
MESPC1M53_02995
MHUAMCHK_6106
MJREB229_02235
MERDEB233_02320
MESRFGU64_17205
MESOBSQ44_22650
HOEIMCC20628_02952
AAKAA2016_1880
AMIHCO731_02015(lcdH_2)
PHTBLM14_08035
NIYFQ775_14145
KMNHW532_09390
SMESMc01638
SMKSinme_2230
SMQSinmeB_2074
SMXSM11_chr1009
SMIBN406_02074(lcdH)
SMEGC770_GR4Chr2309
SMELSM2011_c01638
SMERDU99_12605
SMDSmed_2174
RHINGR_c21580
SFHSFHH103_02054
SFDUSDA257_c45490
SIXBSY16_549
SAMESAMCFNEI73_Ch2520
SINOSS05631_c23070
EADOV14_3671
EAHFA04_11390
ESJSJ05684_c23130
EAKEKH55_2236
EMXFKV68_14620 FKV68_23545 FKV68_23600
ATUAtu5344
ARAArad_9260
ATAAWN88_00065
AVQHRR99_16255
RETRHE_PC00126
RELREMIM1_PB00140
REPIE4803_PD00561
REIIE4771_PE00576
RLEpRL100375
RLTRleg2_4493
RLGRleg_6430
RLBRLEG3_02215
RLURLEG12_05415
RTRRTCIAT899_PC04735
RHLLPU83_pLPU83c0619
RGARGR602_PC01927
RHNAMJ98_PB00183
RPHAAMC79_PA00225
RHXAMK02_PB00197
RHKKim5_PD00534
REZAMJ99_PA00183
RJGCCGE525_28965
RHRCKA34_20725
RADCO657_34185
RIIFFM53_035770
RHIDFFM81_022470
RBQJ2J99_26475
RLNJ0663_29175
RBANJ2J98_28795
RRGJ3P73_33650
RLSHB780_06670
NEOCYG48_22110
NENNCHU2750_44850(lcdH) NCHU2750_48340
RFVRFYW14_00914
SHZshn_12095
SZOK8M09_10825
SOJK6301_09575
OINIAR37_20505
OANOant_2923
OAHDR92_3581
OCHCES85_5191(lcdH)
OCRHGK82_17715
OCLGTN27_20145
BICLMTR13_25405 LMTR13_25515 LMTR13_25660
BGQX265_36365
BGZXH91_35570
BOPAXW83_13330
BOSBSY19_2289
BVVBHK69_27410
SNOSnov_0393
STARG3545_09340
LNEFZC33_26150
ANCGBB76_11735
APOLK9D25_19720
MAQUMaq22A_c00775(fadB)
MEEDA075_12480
MTEADK419_20345
MOCBB934_41920
CHELAL346_10015
MEYTM49_22220
MMEDMame_03227(lcdH_3)
AALAIGS74_01805
AALMLUX29_02940
PSINCAK95_14925
NOHG5V57_30500
PSFPSE_4121
LAPACP90_08760
LABRCHH27_11755
LABPFJ695_03425
LABTFIU93_14315(lcdH1)
LAGGB0E33_20835
PSTGE8M01_34695
LIZLGH83_17830
CAULKCG34_00095
SILSPO1436 SPO2705
SITTM1040_2186
RUAD1823_04130 D1823_08990
RUTFIU92_08815(lcdH1) FIU92_18630(lcdH2)
JANJann_3141 Jann_3827
RDERD1_2523
RLIRLO149_c020370
RPONG3256_10600
DSHDshi_2825
PGAPGA1_c08420
PGLPGA2_c08170
PGDGal_02649
PHPPhaeoP97_00806
PPICPhaeoP14_00764
PHQD1820_17315
OATOAN307_c14250
OAROA238_c09850
OTMOSB_08610(lcdH)
OCTFTO60_11465
LMDMETH_13310 METH_21860
LEJETW24_09935 ETW24_13955 ETW24_20715
LAQUR2C4_04980
REDroselon_00048 roselon_02783
MALGMALG_01861
YPACCEW88_14120 CEW88_18195 CEW88_20150
YANAYJ57_16300
TPROGa0080559_TMP3878
SUAMBOO69_12390 BOO69_20405
SULZC1J03_07620
SULIC1J05_06975 C1J05_14740
SULDB5M07_09530
SPOTG6548_12330 G6548_14585
SMEDJNX03_01150
SINLDSM14862_02683(lcdH_2)
SPSESULPSESMR1_00890(lcdH) SULPSESMR1_02057(lcdH)
TOMBWR18_09725
RMMROSMUCSMR3_03098(lcdH)
ROKRAK1035_1992
RIDRIdsm_00641(lcdH_1) RIdsm_04073(lcdH_4) RIdsm_04439(lcdH_5)
ROMEI983_04460 EI983_04490 EI983_14360
ROHFIU89_04000(lcdH1)
AHTANTHELSMS3_03203
SAGUCDO87_20415
THAACFI11_07980
OCDFHY55_12290
MARUFIU81_05425(lcdH)
MALUKU6B_26090(lcdH)
TGLHFZ77_11325
HATRC74_10280
PALXGQA70_09405
RBLB6K69_06590
PDEPden_5073
PAMIJCM7686_pAMI6p083
PYEA6J80_22330
PCONB0A89_06225
PZHCX676_17225
PAROCUV01_06260
PAMNpAMV3p0253(lcdH)
PARSDRW48_03230
PKDF8A10_00640
PPANESD82_10260
PLIAE4191_05790 E4191_09680
PMAUCP157_02017(lcdH_2)
PTPRCA23_c22110 RCA23_c29140
RSUNHU_02651(lcdH)
RHMB5V46_11125
RHCRGUI_3129
RMBK529_002940
DAAAKL17_0015
DONBSK21_10345
LVSLOKVESSMR4R_02268(lcdH)
GEHHYN69_15655
GFUKM031_05395
TAWEI545_14055
SALOEF888_07895
SEDIEBB79_03425 EBB79_05585 EBB79_22475
HMLHmaOT1_14475 HmaOT1_17990
BOOE2K80_18725
PSEBEOK75_06675 EOK75_14590
PPRUFDP22_03430
PAEDG5B38_01460 G5B38_05430 G5B38_10265
PAMOBAR1_01820 BAR1_10915
PSHQF3W81_06490 F3W81_08230
PALWPSAL_035480(lcdH_1) PSAL_036210(lcdH_2)
PGVSL003B_0536
CACTHZ995_01130
RBZB9057_03260
THASC6Y53_04540 C6Y53_10965
HDHG5B40_03905
GCEKYE46_03980
NSMJO391_19385
SPHKSKP52_01085(lcdH)
SPHDHY78_26515
SECHB18_08840
SYBTZ53_05555
SYAA6768_12345
SUFLFIL70_21970
SBARH5V43_18990
AACEA0U92_02205
ABQABAZ39_29140
ATIAL072_21190
AZMDM194_13930 DM194_21840
AZZDEW08_26055
AOZHUE56_07700
NAOY958_14855
SKTIGS68_11365
SMUCJL100_013415
SROEJL101_012780
TMOTMO_1135 TMO_b0425
FERFNB15_08945
HTQFRZ44_22810 FRZ44_27550(lcdH)
HADHFRZ61_19890(lcdH) FRZ61_24410
THACCSC3H3_05660 CSC3H3_23945
TIIDY252_20650
SNEANBZ79_16045
BCZpE33L466_0384(hbd)
BCYBcer98_0770
PARHI5S86_27360
BLEBleG1_1603
OIHOB0997
HHDHBHAL_4278
HMNHM131_14605
HLIHLI_16415
VIRX953_18040
VHLBME96_17510
VILCFK37_06815
VNECFK40_02195
LAOAOX59_16635
SJEAAV35_010990
GRCGI584_06120
RUEDT065_16690
SALEEPH95_16095 EPH95_16470
SCIBHUG20_13925
SCIAHUG15_06480
POFGS400_01160
SEDDERJ70_06495
SERSERP2360
SEPSE_0220
SEPPSEB_00146
SEPSDP17_1248
SSPSSP0449
SCASCA_0090
SXYBE24_09735
SXLSXYLSMQ121_0483
SXOSXYL_00486(lcdH)
SEQOSE1039_21180
SSIFAL483_10580
SCVA4G25_07285
SNLBJD96_02610
SKLC7J89_03935
SARLSAP2_05490(lcdH)
SLLOISP08_02645
SHVAAT16_10610
PLNPlano_2658
PKUAUO94_02245
PLLI858_009430
PDGBCM40_01820
PHCBBI08_10690
PFAEAJGP001_15375
SPAEE2C16_04750
PANCE2636_03425
KPULGXN76_04130
CLSCXIVA_10660(FadB)
FPLAA4U99_02415 A4U99_15915
CCTCC1_14980 CC1_30800
IBUIB211_02424c
NTHNther_1018
MFTXA26_04120
MMATMMAGJ_75590(lcdH)
TPRTpau_2225
SCOSCO6297(SCBAC8D1.10c)
SALBXNR_0008 XNR_5931
SGRSGR_6649
SGBWQO_01850
SVLStrvi_1044
SRCM271_20580 M271_34120
SMALSMALA_4613
SSOII1A49_27125
SALLSAZ_35445
SLVSLIV_06660(lcdH)
STREGZL_01945
SLDT261_1153
SLCSL103_23430
SPAVSpa2297_03255
SKYD0C37_00325 D0C37_31745
SNRSNOUR_08685(lcdH)
STRDNI25_07920
SAUOBV401_26915
SSIAA7J05_05620
SVUB1H20_01420
SLAUSLA_7086
SALFSMD44_07202(lcdH)
SFKKY5_7002
SKACP970_05050
SBYH7H31_32085
SRIMCP984_05455
SPACB1H29_33285
SGXH4W23_04780
SBATG4Z16_12665
SPLACP981_32640
SDWK7C20_31215
SCALI6J39_01525
SAUHSU9_029600
SXNIAG42_03645
SANUK7396_06060
SINEKI385_37045
SLFJEQ17_38855
KITCFP65_0450
SATKSA2016_4012
BRXBH708_15830
BRVCFK39_10445
BRZCFK38_00275
ARSADJ73_05975
BLYA2T55_08570
BLINBLSMQ_1403 BLSMQ_1831
BCAUI6G59_01310 I6G59_11840
NOYEXE57_03925
NANOG5V58_19850
NROK8W59_14485
NDANdas_1341
NALB005_0601
STRREKD16_07875(lcdH2)
SAIUJ4H86_06990
SROSros_5041
SENSACE_3866
SACGFDZ84_36055
SVISvir_16250
AMYCCU254_19720
AMYYYIM_28040(lcdH2)
PSEAWY02_01635
PSEEFRP1_10610
PSEHXF36_09860
PSEQAD006_20345
PECQAD017_28185
PHHAFB00_26690
PAUTPdca_17680(fadB_2) Pdca_35570(lcdH)
PBROHOP40_01115
PMADBAY61_12365
SACEGIY23_13570
PBORBSF38_02080(lcdH)
TALBFTW19_13300
 » show all
Reference
1  [PMID:4302217]
  Authors
Aurich H, Kleber HP, Sorger H, Tauchert H
  Title
[Purification and properties of carnitine dehydrogenase from Pseudomonas aeruginosa].
  Journal
Eur J Biochem 6:196-201 (1968)
DOI:10.1111/j.1432-1033.1968.tb00437.x
  Sequence
[pae:PA5386]
Reference
2  [PMID:4310279]
  Authors
Schopp W, Sorger H, Kleber HP, Aurich H.
  Title
[Kinetic studies of the reaction mechanism of carnitine dehydrogenase of Pseudomonas aeruginosa]
  Journal
Eur J Biochem 10:56-60 (1969)
DOI:10.1111/j.1432-1033.1969.tb00654.x
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.108
IUBMB Enzyme Nomenclature: 1.1.1.108
ExPASy - ENZYME nomenclature database: 1.1.1.108
BRENDA, the Enzyme Database: 1.1.1.108
CAS: 9045-45-8
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