KEGG ENZYME: 1.1.1.119

ENZYME: 1.1.1.119

Entry

EC 1.1.1.119                Enzyme

Name

glucose 1-dehydrogenase (NADP+);
nicotinamide adenine dinucleotide phosphate-linked aldohexose dehydrogenase;
NADP+-linked aldohexose dehydrogenase;
NADP+-dependent glucose dehydrogenase;
glucose 1-dehydrogenase (NADP+)

Class

Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor

Sysname

D-glucose:NADP+ 1-oxidoreductase

Reaction(IUBMB)

D-glucose + NADP+ = D-glucono-1,5-lactone + NADPH + H+ [RN:R07147]

Reaction(KEGG)

R07147;
(other) R00301

Substrate

D-glucose [CPD:C00031];
NADP+ [CPD:C00006]

Product

D-glucono-1,5-lactone [CPD:C00198];
NADPH [CPD:C00005];
H+ [CPD:C00080]

Comment

Also oxidizes D-mannose, 2-deoxy-D-glucose and 2-amino-2-deoxy-D-mannose.

History

EC 1.1.1.119 created 1972

Reference

Authors

Adachi O, Ameyama M.

Title

D-Glucose dehydrogenase from Gluconobacter suboxydans.

Journal

Methods Enzymol 89:159-163 (1982)

Reference

2 [PMID:4384672]

Authors

Avigad G, Alroy Y, Englard S.

Title

Purification and properties of a nicotinamide adenine dinucleotide phosphate-linked aldohexose dehydrogeanse from Gluconobacter cerinus.

Journal

J Biol Chem 243:1936-41 (1968)

Other DBs

ExplorEnz - The Enzyme Database:

1.1.1.119

IUBMB Enzyme Nomenclature:

1.1.1.119

ExPASy - ENZYME nomenclature database:

1.1.1.119

BRENDA, the Enzyme Database:

1.1.1.119

CAS:	37250-50-3

LinkDB

DBGET integrated database retrieval system