KEGG   ENZYME: 1.1.1.121
Entry
EC 1.1.1.121                Enzyme                                 
Name
aldose 1-dehydrogenase (NAD+);
aldose dehydrogenase;
D-aldohexose dehydrogenase;
aldose 1-dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
D-aldose:NAD+ 1-oxidoreductase
Reaction(IUBMB)
D-aldose + NAD+ = D-aldonolactone + NADH + H+ [RN:R02847]
Reaction(KEGG)
Substrate
D-aldose [CPD:C00737];
NAD+ [CPD:C00003]
Product
D-aldonolactone [CPD:C16830];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Acts on D-glucose, 2-deoxy- and 6-deoxy-D-glucose, D-galactose, 6-deoxy-D-galactose, 2-deoxy-L-arabinose and D-xylose.
History
EC 1.1.1.121 created 1972
Reference
1  [PMID:5845847]
  Authors
Cline AL, Hu AS.
  Title
The isolation of three sugar dehydrogenases from a psuedomonad.
  Journal
J Biol Chem 240:4488-92 (1965)
Reference
2  [PMID:5845848]
  Authors
Cline AL, Hu AS.
  Title
Enzymatic characterization and comparison of three sugar dehydrogenases from a pseudomonad.
  Journal
J Biol Chem 240:4493-7 (1965)
Reference
3  [PMID:5845849]
  Authors
Cline AL, Hu AS.
  Title
Some physical properties of three sugar dehydrogenases from a pseudomonad.
  Journal
J Biol Chem 240:4498-502 (1965)
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.121
IUBMB Enzyme Nomenclature: 1.1.1.121
ExPASy - ENZYME nomenclature database: 1.1.1.121
BRENDA, the Enzyme Database: 1.1.1.121
CAS: 9076-61-3
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