KEGG   ENZYME: 1.1.1.137
Entry
EC 1.1.1.137                Enzyme                                 
Name
ribitol-5-phosphate 2-dehydrogenase;
ribitol 5-phosphate dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
D-ribitol-5-phosphate:NAD(P)+ 2-oxidoreductase
Reaction(IUBMB)
D-ribitol 5-phosphate + NAD(P)+ = D-ribulose 5-phosphate + NAD(P)H + H+ [RN:R01524 R01525]
Reaction(KEGG)
R01524 R01525
Substrate
D-ribitol 5-phosphate [CPD:C01068];
NAD+ [CPD:C00003];
NADP+ [CPD:C00006]
Product
D-ribulose 5-phosphate [CPD:C00199];
NADH [CPD:C00004];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
The enzyme, characterized from the bacterium Lactobacillus plantarum, can use both NAD+ and NADP+ as electron acceptor [cf. EC 1.1.1.405, ribitol-5-phosphate 2-dehydrogenase (NADP+)].
History
EC 1.1.1.137 created 1972, modified 2017
Pathway
ec00040  Pentose and glucuronate interconversions
ec01100  Metabolic pathways
Orthology
K21680  ribulose-5-phosphate 2-dehydrogenase
Genes
LPL: lp_1817(tarJ)
LPJ: JDM1_1530
LPT: zj316_1805(tarJ)
LPS: LPST_C1459
LPR: LBP_cg1413
LPZ: Lp16_1406
LPB: SH83_07560
LPX: ASU28_07560
LPG: BB562_08400
LARG: LPA65_07280
Reference
1  [PMID:13948358]
  Authors
GLASER L.
  Title
Ribitol-5-phosphate dehydrogenase from Lactobacillus plantarum.
  Journal
Biochim Biophys Acta 67:525-30 (1963)
DOI:10.1016/0006-3002(63)91863-8
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.137
IUBMB Enzyme Nomenclature: 1.1.1.137
ExPASy - ENZYME nomenclature database: 1.1.1.137
BRENDA, the Enzyme Database: 1.1.1.137
CAS: 37250-67-2
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