KEGG   ENZYME: 1.1.1.198
Entry
EC 1.1.1.198                Enzyme                                 
Name
(+)-borneol dehydrogenase;
bicyclic monoterpenol dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
(+)-borneol:NAD+ oxidoreductase
Reaction(IUBMB)
(+)-borneol + NAD+ = (+)-camphor + NADH + H+ [RN:R02944]
Reaction(KEGG)
R02944
Substrate
(+)-borneol [CPD:C01765];
NAD+ [CPD:C00003]
Product
(+)-camphor [CPD:C00808];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
NADP+ can also act, but more slowly.
History
EC 1.1.1.198 created 1984, modified 1990 (EC 1.1.1.182 created 1983, part incorporated 1990)
Pathway
ec00902  Monoterpenoid biosynthesis
ec01110  Biosynthesis of secondary metabolites
Reference
1  [PMID:677891]
  Authors
Croteau R, Hooper CL, Felton M.
  Title
Biosynthesis of monoterpenes. Partial purfication and characterization of a bicyclic monoterpenol dehydrogenase from sage (Salvia officinalis).
  Journal
Arch Biochem Biophys 188:182-93 (1978)
DOI:10.1016/0003-9861(78)90371-5
Reference
2  [PMID:3310901]
  Authors
Dehal SS, Croteau R.
  Title
Metabolism of monoterpenes: specificity of the dehydrogenases responsible for the biosynthesis of camphor, 3-thujone, and 3-isothujone.
  Journal
Arch Biochem Biophys 258:287-91 (1987)
DOI:10.1016/0003-9861(87)90346-8
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.198
IUBMB Enzyme Nomenclature: 1.1.1.198
ExPASy - ENZYME nomenclature database: 1.1.1.198
BRENDA, the Enzyme Database: 1.1.1.198
CAS: 111940-47-7
LinkDB

KEGG   REACTION: R02944
Entry
R02944                      Reaction                               
Name
(+)-borneol:NAD+ oxidoreductase
Definition
(+)-Borneol + NAD+ <=> (+)-Camphor + NADH + H+
Equation
C01765 + C00003 <=> C00808 + C00004 + C00080
Reaction class
RC00001  C00003_C00004
RC00127  C00808_C01765
Enzyme
1.1.1.198
Pathway
rn00902  Monoterpenoid biosynthesis
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.198
     R02944  (+)-Borneol + NAD+ <=> (+)-Camphor + NADH + H+
Other DBs
RHEA: 17332
LinkDB

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