KEGG   ENZYME: 1.1.1.275
Entry
EC 1.1.1.275                Enzyme                                 
Name
(+)-trans-carveol dehydrogenase;
carveol dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
(+)-trans-carveol:NAD+ oxidoreductase
Reaction(IUBMB)
(+)-trans-carveol + NAD+ = (+)-(S)-carvone + NADH + H+ [RN:R06117]
Reaction(KEGG)
R06117
Substrate
(+)-trans-carveol [CPD:C11409];
NAD+ [CPD:C00003]
Product
(+)-(S)-carvone [CPD:C11383];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
NADP+ cannot replace NAD+. Forms part of the monoterpenoid biosynthesis pathway in Carum carvi (caraway) seeds.
History
EC 1.1.1.275 created 2003
Pathway
ec00902  Monoterpenoid biosynthesis
ec00903  Limonene degradation
ec01120  Microbial metabolism in diverse environments
Orthology
K12466  (+)-trans-carveol dehydrogenase
Genes
ROP: ROP_13700
ROA: Pd630_LPD05811
RKO: JWS14_08535
ROZ: CBI38_33290
RPSK: JWS13_37630
RHOJ: JVH1_28995
GPD: GII33_04360
Reference
1  [PMID:9662532]
  Authors
Bouwmeester HJ, Gershenzon J, Konings MC, Croteau R.
  Title
Biosynthesis of the monoterpenes limonene and carvone in the fruit of caraway. I. Demonstration Of enzyme activities and their changes with development
  Journal
Plant Physiol 117:901-12 (1998)
DOI:10.1104/pp.117.3.901
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.275
IUBMB Enzyme Nomenclature: 1.1.1.275
ExPASy - ENZYME nomenclature database: 1.1.1.275
BRENDA, the Enzyme Database: 1.1.1.275
LinkDB

KEGG   REACTION: R06117
Entry
R06117                      Reaction                               
Name
(+)-trans-carveol: NAD+ oxidoreductase
Definition
(+)-trans-Carveol + NAD+ <=> (+)-(S)-Carvone + NADH + H+
Equation
C11409 + C00003 <=> C11383 + C00004 + C00080
Reaction class
RC00001  C00003_C00004
RC00850  C11383_C11409
Enzyme
1.1.1.275
Pathway
rn00902  Monoterpenoid biosynthesis
rn00903  Limonene degradation
rn01120  Microbial metabolism in diverse environments
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.275
     R06117  (+)-trans-Carveol + NAD+ <=> (+)-(S)-Carvone + NADH + H+
Orthology
K12466  (+)-trans-carveol dehydrogenase [EC:1.1.1.275]
Other DBs
RHEA: 14828
LinkDB

DBGET integrated database retrieval system