| Entry |
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| Name |
(S)-3-hydroxyacid-ester dehydrogenase;
3-oxo ester (S)-reductase
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| Class |
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
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| Sysname |
ethyl-(S)-3-hydroxyhexanoate:NADP+ 3-oxidoreductase
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| Reaction(IUBMB) |
ethyl (S)-3-hydroxyhexanoate + NADP+ = ethyl 3-oxohexanoate + NADPH + H+ [RN: R04106]
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| Reaction(KEGG) |
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| Substrate |
ethyl (S)-3-hydroxyhexanoate [CPD: C03865];
NADP+ [CPD: C00006]
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| Product |
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| Comment |
Also acts on 4-oxo- and 5-oxo-fatty acids and their esters. cf. EC 1.1.1.279 (R)-3-hydroxyacid-ester dehydrogenase.
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| History |
EC 1.1.1.280 created 1990 as EC 1.2.1.56, transferred 2003 to EC 1.1.1.280
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| Reference |
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| Authors |
Heidlas J, Engel KH, Tressl R. |
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| Title |
Purification and characterization of two oxidoreductases involved in the enantioselective reduction of 3-oxo, 4-oxo and 5-oxo esters in baker's yeast. |
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| Journal |
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| Other DBs |
| ExPASy - ENZYME nomenclature database: | 1.1.1.280 |
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| LinkDB |
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