| Entry |
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| Name |
L-arabinose 1-dehydrogenase [NAD(P)+];
L-arabino-aldose dehydrogenase
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| Class |
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
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| Sysname |
L-arabinose:NAD(P)+ 1-oxidoreductase
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| Reaction(IUBMB) |
L-arabinose + NAD(P)+ = L-arabinono-1,4-lactone + NAD(P)H + H+ [RN: R01757 R10787]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
The enzymes from the bacterium Azospirillum brasilense and the archaeon Haloferax volcanii are part of the L-arabinose degradation pathway and prefer NADP+ over NAD+. In vitro the enzyme from Azospirillum brasilense shows also high catalytic efficiency with D-galactose.
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| History |
EC 1.1.1.376 created 2014
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| Pathway |
| ec00053 | Ascorbate and aldarate metabolism |
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| Orthology |
| K13873 | L-arabinose 1-dehydrogenase |
| K19660 | L-arabinose 1-dehydrogenase [NAD(P)+] |
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| Genes |
» show all
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| Reference |
1 |
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| Authors |
Novick, N.J. and Tyler, M.E. |
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| Title |
Partial purification and properties of an L-arabinose dehydrogenase from Azospirillum brasilense. |
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| Journal |
Can J Microbiol 29:242-246 (1983) |
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| Reference |
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| Authors |
Watanabe S, Kodaki T, Makino K |
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| Title |
Cloning, expression, and characterization of bacterial L-arabinose 1-dehydrogenase involved in an alternative pathway of L-arabinose metabolism. |
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| Journal |
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| Sequence |
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| Reference |
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| Authors |
Johnsen U, Sutter JM, Zaiss H, Schonheit P |
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| Title |
L-Arabinose degradation pathway in the haloarchaeon Haloferax volcanii involves a novel type of L-arabinose dehydrogenase. |
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| Journal |
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| Sequence |
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| Other DBs |
| ExPASy - ENZYME nomenclature database: | 1.1.1.376 |
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| LinkDB |
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