The enzyme, found in bacteria and fungi, can also accept a number of substituted mandelate derivatives, such as 3-hydroxymandelate, 4-hydroxymandelate, 2-methoxymandelate, 4-hydroxy-3-methoxymandelate and 3-hydroxy-4-methoxymandelate. The enzyme has no activity with (S)-mandelate (cf. EC 188.8.131.52, (S)-mandelate dehydrogenase) [1,2]. The enzyme transfers the pro-R-hydrogen from NADH .
EC 184.108.40.2069 created 2014
Baker, D.P. and Fewson, C.A.
Purification and characterization of D(-)-mandelate dehydrogenase from Rhodotorula graminis.