Entry
Name
2-dehydro-3-deoxy-L-rhamnonate dehydrogenase (NAD+);
2-keto-3-deoxy-L-rhamnonate dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
2-dehydro-3-deoxy-L-rhamnonate:NAD+ 4-oxidoreductase
Reaction(IUBMB)
2-dehydro-3-deoxy-L-rhamnonate + NAD+ = 2,4-didehydro-3-deoxy-L-rhamnonate + NADH + H+ [RN:
R11339 ]
Reaction(KEGG)
Substrate
2-dehydro-3-deoxy-L-rhamnonate [CPD:
C03979 ];
NAD+ [CPD:
C00003 ]
Product
Comment
The enzyme, characterized from the bacteria Sphingomonas sp. SKA58 and Sulfobacillus thermosulfidooxidans, is involved in the non-phosphorylative degradation pathway for L-rhamnose. It does not show any detectable activity with NADP+ or with other aldoses.
History
EC 1.1.1.401 created 2016
Pathway
ec00051 Fructose and mannose metabolism
ec01120 Microbial metabolism in diverse environments
Orthology
K21883 2-dehydro-3-deoxy-L-rhamnonate dehydrogenase (NAD+)
Genes
XPH : XppCFBP6546_02695(XppCFBP6546P_02695)
GAI : IMCC3135_16660(fabG_4)
REH : H16_B1075(h16_B1075)
CNC : CNE_2c10320(fabG7) CNE_BB1p11630(fabG16)
BYI : BYI23_B004390 BYI23_B007570 BYI23_C012390 BYI23_D004990
BUE : BRPE67_BCDS07010 BRPE67_BCDS11520 BRPE67_CCDS14200 BRPE67_DCDS06790
BUM : AXG89_17650 AXG89_39135
BUI : AX768_21210 AX768_27430
BXE : Bxe_A2719 Bxe_B1028 Bxe_C0296
BXB : DR64_403 DR64_6349 DR64_8137
BPH : Bphy_3470 Bphy_6096 Bphy_6716
BCAI : K788_0006074 K788_0008440 K788_0008516
PARB : CJU94_23875 CJU94_35365
PHS : C2L64_21010 C2L64_22515 C2L64_33470 C2L64_40795
PTER : C2L65_25445 C2L65_30060
PCJ : CUJ87_23080 CUJ87_29425
PTRO : G5S35_23000 G5S35_23835
PGIS : I6I06_22805 I6I06_24305
PACP : FAZ97_21170 FAZ97_29965
PACS : FAZ98_17360 FAZ98_27105
PSAA : QEN71_12650 QEN71_30000 QEN71_31015
PKF : RW095_08765 RW095_19215
PLAD : PPGU16_41660(fabG_5) PPGU16_58890 PPGU16_64130(fabG_8) PPGU16_65860 PPGU16_74310(fabG_9)
BUO : BRPE64_BCDS05680 BRPE64_BCDS08830 BRPE64_CCDS02950
CABK : NK8_34370 NK8_37390 NK8_50690 NK8_75990 NK8_76400
BFZ : BAU07_03410 BAU07_08710
BOH : AKI39_16775 AKI39_21445
AKA : TKWG_22980 TKWG_24470
AMIM : MIM_c37220 MIM_c39460
RHY : RD110_04410 RD110_09810 RD110_13105 RD110_25030
VPE : Varpa_0812 Varpa_4230
VPD : VAPA_1c08500 VAPA_1c34560 VAPA_1c40710
VBO : CKY39_03990 CKY39_23990
VAZ : H7F35_01195 H7F35_16080
VAV : IG196_02355 IG196_21190
LIM : L103DPR2_00634(fabG_5)
LIH : L63ED372_02617(fabG_7)
HSE : Hsero_0584(fabG) Hsero_1263(fabG)
HSZ : ACP92_02925 ACP92_06345
HHT : F506_05085 F506_06205
HEE : hmeg3_06350 hmeg3_20535
HHF : E2K99_03270 E2K99_06180
HFR : G5S34_03150 G5S34_06475
URU : DSM104443_01671(lra5)
UPL : DSM104440_01594(lra5)
MLN : A9174_01320 A9174_27675
MCI : Mesci_0269 Mesci_0299
MCIC : A4R28_26875 A4R28_27025
MESW : A9K65_001345 A9K65_001495 A9K65_021660
MESP : C1M53_17335 C1M53_28885
MHUA : MCHK_1138 MCHK_6293
MJR : EB229_01345 EB229_27935
ATU : Atu3813(fabG) Atu4595
ALEG : CFBP4996_28050 CFBP4996_28970
NEN : NCHU2750_48930(fabG)
BJA : bll3655(bll3655) bll3913(fabG) bll6359(bll6359)
BVZ : BRAD3257_2220 BRAD3257_5027 BRAD3257_5135(fabG)
BBAN : J4G43_002850 J4G43_021855
RBK : E0H22_11315 E0H22_14510
VGO : GJW-30_1_00198(fabG_1)
BVV : BHK69_05300 BHK69_29605
BVES : QO058_17505 QO058_21335 QO058_28760 QO058_29165
BOP : AXW83_06685 AXW83_15660 AXW83_15690 AXW83_20390
BOS : BSY19_1292 BSY19_346
BOI : BLM15_15895 BLM15_16500 BLM15_19670
BOF : FQV39_13175 FQV39_13575 FQV39_14755 FQV39_17890 FQV39_19460 FQV39_30970
BOSE : RMR04_28730 RMR04_30060
XDI : EZH22_08125 EZH22_12750
STAR : G3545_16255 G3545_27160
LNE : FZC33_13720 FZC33_22295 FZC33_26780
APRA : G3A50_04745 G3A50_07825
AQI : J5J86_02600 J5J86_11530 J5J86_14735
MNO : Mnod_2255 Mnod_2895 Mnod_6624
MAQU : Maq22A_c13140(fabG)
MOC : BB934_14870 BB934_28775
CHEL : AL346_08150 AL346_11895
CDQ : BOQ54_01270 BOQ54_04120
DEA : FPZ08_14720 FPZ08_18035
DAG : PSQ19_17155 PSQ19_17815
MHAR : L1P08_03275 L1P08_15160
MMED : Mame_04374(actIII_3)
RPOP : K1718_07155 K1718_20950
ACUT : MRB58_15425 MRB58_21970
TSV : DSM104635_01778(fabG_4)
KRO : BVG79_p1000086(fabG)
SMED : JNX03_16185 JNX03_16965
SPSE : SULPSESMR1_01364(fabG)
SAGU : CDO87_12725 CDO87_23165 CDO87_25655
PALX : GQA70_22770 GQA70_22835
PTP : RCA23_c06680 RCA23_c11890 RCA23_c23530
STAX : MC45_07210 MC45_07305
SPAG : sphantq_01937(LRA5)
RGI : RGI145_21810 RGI145_22280
NCB : C0V82_17100 C0V82_24305
SROE : JL101_033735 JL101_034715
NACI : NUH88_12625 NUH88_20605
PUB : SAR11_0767 SAR11_0846 SAR11_0869
PEG : E5R92_01630 E5R92_02215
CMIC : caldi_13000(fabG_3)
RKO : JWS14_09535 JWS14_41825
PSEK : GCM125_12460(fabG_2)
SLOM : PXH66_00685 PXH66_17160
SDYN : Mal52_25750(fabG_5)
GMS : SOIL9_18330 SOIL9_49820
FLC : KJS93_09855 KJS93_18560
SRD : SD10_04060 SD10_11620
SPIK : EXU85_20030 EXU85_24690
SFOL : H3H32_05730 H3H32_14585
» show all
Taxonomy
Reference
Authors
Watanabe S, Makino K
Title
Novel modified version of nonphosphorylated sugar metabolism--an alternative L-rhamnose pathway of Sphingomonas sp.
Journal
Sequence
Reference
Authors
Bae J, Kim SM, Lee SB
Title
Identification and characterization of 2-keto-3-deoxy-L-rhamnonate dehydrogenase belonging to the MDR superfamily from the thermoacidophilic bacterium Sulfobacillus thermosulfidooxidans: implications to L-rhamnose metabolism in archaea.
Journal
Other DBs
ExPASy - ENZYME nomenclature database: 1.1.1.401
LinkDB
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