| Entry |
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| Name |
dimethylmalate dehydrogenase;
beta,beta-dimethylmalate dehydrogenase
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| Class |
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
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| Sysname |
(R)-3,3-dimethylmalate:NAD+ oxidoreductase (decarboxylating)
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| Reaction(IUBMB) |
(R)-3,3-dimethylmalate + NAD+ = 3-methyl-2-oxobutanoate + CO2 + NADH [RN: R01211]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
Requires K+ or NH4+ and Mn2+ or Co2+; also acts on (R)-malate.
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| History |
EC 1.1.1.84 created 1972
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| Pathway |
| ec00770 | Pantothenate and CoA biosynthesis |
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| Reference |
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| Authors |
Magee PT, Snell EE. |
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| Title |
The bacterial degradation of pantothenic acid. IV. Enzymatic conversion of aldopantoate to alpha-ketoisovalerate. |
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| Journal |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 1.1.1.84 |
| ExPASy - ENZYME nomenclature database: | 1.1.1.84 |
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| LinkDB |
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