KEGG   ENZYME: 1.1.2.11
Entry
EC 1.1.2.11                 Enzyme                                 
Name
glucoside 3-dehydrogenase (cytochrome c);
D-glucoside 3-dehydrogenase (ambiguous);
D-aldohexopyranoside dehydrogenase (ambiguous);
D-aldohexoside:cytochrome c oxidoreductase;
hexopyranoside-cytochrome c oxidoreductase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With a cytochrome as acceptor
Sysname
a D-glucoside:ferric c-type cytochrome 3-oxidoreductase
Reaction(IUBMB)
a D-glucoside + a ferric c-type cytochrome = a 3-dehydro-D-glucoside + a ferrous c-type cytochrome [RN:R13010]
Reaction(KEGG)
R13010
Substrate
D-glucoside [CPD:C01798];
ferric c-type cytochrome
Product
3-dehydro-D-glucoside [CPD:C22515];
ferrous c-type cytochrome
Comment
This bacterial enzyme acts on D-glucose, D-galactose, D-glucosides and D-galactosides, but the best substrates are disaccharides with a glucose moiety at the non-reducing end. It consists of two subunits, a catalytic subunit that contains an FAD cofactor and an iron-sulfur cluster, and a "hitch-hiker" subunit containing a signal peptide for translocation into the periplasm. A dedicated c-type cytochrome protein serves as an electron acceptor, transferring the electrons from the catalytic subunit to the cell's electron transfer chain. cf. EC 1.1.99.13, glucoside 3-dehydrogenase (acceptor).
History
EC 1.1.2.11 created 2022
Orthology
K26059  glucoside 3-dehydrogenase (cytochrome c) catalytic subunit
Genes
XSASB85_19180
XPRMUG10_17350
SMLSmlt1189
SMTSmal_1042
BUJBurJV3_1030
SMZSMD_1110
STEKAXG53_11945
SRHBAY15_1184
SLMBIZ42_14485
STENCCR98_05535
STEMCLM74_05525
STESMG068_05155
SINCDAIF1_10980(fdhL_1)
SPAQSTNY_R11600
PJPLAG73_15755
LCPLC55x_4887
LGULG3211_4767
LEZGLE_2604
LEMLEN_2537(chd)
DJICH75_07965
DJAHY57_13800
DTLH8F01_20920
DTADYST_01541
LRZBJI69_17815
LPYFIV34_01215
LANHKR767_15525
SWPswp_4566
CBERB5D82_17160
THAPFNC98_01770
PATPatl_2686
AMCMADE_1002110
AMHI633_01895
AMAAamad1_01955
AMALI607_01925
AMAEI876_02105
AMAOI634_02170
AMADI636_01975
AMAII635_01960
AMAGI533_01880
AMACMASE_01345
AMBAMBAS45_01595
AMGAMEC673_01410
AMKAMBLS11_01670
ALTambt_16610
AALEP13_01870 EP13_04275
AAUSEP12_01845
ASPAOR13_3174
ASQAVL57_02915
AAWAVL56_01635
ALRDS731_00790 DS731_01080 DS731_04930 DS731_16810 DS731_19245
ALEAV939_01730 AV939_12230
ALZAV940_01725 AV940_11995
APELCA267_011470 CA267_016770
SALMD0Y50_12005 D0Y50_17785
SALKFBQ74_01510
GAGGlaag_1605 Glaag_3241
GPSC427_0563 C427_3053
PMESFX988_01543 FX988_04202
LALAT746_00170 AT746_00190
CJACJA_3101
CEBB0D95_11535 B0D95_14055
CELLCBR65_04570 CBR65_16515
CEKD0B88_04270 D0B88_06850
CEGD0C16_20350
SDESde_1033
MTHDA3224_13355
MIIBTJ40_06390
MCELLPW13_12780
HJABST95_12605
HALCEY643_09840
AFUSEYZ66_11690
HELHELO_1209(lacA)
HAMHALO1164
HHUAR456_09955
HOLHORIV_53400
HMDCTT34_14590
HTTHZS52_10680
HPROLMS44_17230
PSPIPS2015_2240
MASWAM586_03355
MALIEYF70_11180
MUMFCL38_07550 FCL38_30260
MFLAGO485_02965
MPLIE1742_04195
ATUAtu4377
ATAAWN88_09505
AGRAGROH133_06059
ATFAch5_13670
AROB0909_16000
AGTEYD00_15670
RIRBN877_II0387
RPUSCFBP5875_15840
RHVBA939_25150
ROYG3A56_23800
CAENK5X80_13585
CCRCC_1634
CCSCCNA_01706
CAKCaul_0419 Caul_4606
CSECseg_2107
CAUFCSW63_11550
PZUPHZ_c2153
PHBHYN04_12575
KVLKVU_0018
KROBVG79_p1000152(betA)
PARREOJ32_13365
PLIAE4191_21965
PMAUCP157_00932(fdhL_2)
NARSaro_1208 Saro_3164
NPPPP1Y_Mpl7524
NREBES08_18845
NOVTQ38_018475
NOTC7W88_20495
SPHKSKP52_15880
SPHXE5675_02890
SPHUSPPYR_0169
SWISwit_1632 Swit_1894
SPHDHY78_16100 HY78_17425
SPHITS85_04780
SSANNX02_03565 NX02_17185
SPANAWL63_13110
SKRBRX40_12095
SPLMBXU08_06665
SPLKAV944_06190
SPHCCVN68_02540
SPAUDRN02_018095
SPAPH3Z74_18100
SPIIG7077_04545
SSUAFPZ54_09165 FPZ54_10765
SBINSBA_ch2_5040
SAERNEF64_01065
SQONMP03_05525 NMP03_12815
SCHSphch_3333
SYAA6768_07085 A6768_22545
SPYGYGS_C2P1048
SAMISAMIE_1030100
PHAOHF685_05635
SPHSETR14_14330
PMEAKTC28_05095
CMANA9D14_17345
NAOY958_05220
NCBC0V82_03460 C0V82_18550
ECOGFIV45_03575
OBGVerru16b_02225(fdhL_1)
TRSTerro_2899
EDAGWR55_12280
EDGH7846_09460
GAUGAU_3131
GPHGEMMAAP_07015 GEMMAAP_16030
GGRHKW67_03755
GBAJ421_4769
RMRRmar_1737 Rmar_1738
RMGRhom172_1709
RBARAWN76_003120 AWN76_011750
CPICpin_3694 Cpin_5415 Cpin_5416
CBAECOR50_15745 COR50_15750
CHITFW415_18905
CHIHGWR21_07690 GWR21_07695
COYHF329_02565 HF329_02570 HF329_06890
CFILMYF79_19425 MYF79_22455 MYF79_22460
CHFKTO58_06205 KTO58_06210
NKONiako_4747 Niako_6253 Niako_6254
NSONIASO_01055 NIASO_01200
NIAA8C56_01535 A8C56_06475 A8C56_12710
FLASY85_02915
FGGFSB75_06040
ARBA9P82_10750
AGIFSB73_08440
ARACE0W69_018035
ATEEK9M52_08845
FLNFLA_1527
PSEGD3H65_23565 D3H65_23570
PGINFRZ67_10645 FRZ67_10650 FRZ67_10665 FRZ67_13155
PGOFSB84_06395
FLSGLV81_04305 GLV81_07360 GLV81_07460
LACSH4075_20645 H4075_20650
FLCKJS93_09385
FLVKJS94_07525 KJS94_07530
SEDTTEGAF0_01480 TEGAF0_18080
HHYHalhy_3106 Halhy_5995
PHEPhep_1967 Phep_2474 Phep_3645
PEPAQ505_03335 AQ505_10185 AQ505_15695 AQ505_19940
PCMAY601_0203 AY601_0997 AY601_4788
PSTYBFS30_08055 BFS30_19470 BFS30_26085
PGSCPT03_09075 CPT03_15285
PEJFYC62_11965
PEKFFJ24_015780
PROEH9L23_16635
PEXIZT61_18805
PMUOLOK61_12390
PSNPedsa_3787
SHGSph21_0176 Sph21_3642
SHTKO02_06280
SPHNBV902_16590
SMIZ4412673_02814
SPSCE2P86_07800
SPHZE3D81_06430
SPHEGFH32_05590
SPDRG6053_11955 G6053_25355
SDJNCTC13534_04012
STHANCTC11429_02580 NCTC11429_04773
SSPII6J01_00810
SMUII6J00_05610
SSIYJVX97_15200
MUPA0256_07355 A0256_12600 A0256_15620
MUCMuYL_3026 MuYL_3325
MGOTMgSA37_02853 MgSA37_03313(fdhL_2) MgSA37_03314(fdhL_3)
MUHHYN43_005565 HYN43_012175
MGINFRZ54_17105 FRZ54_18145 FRZ54_20095
MGKFSB76_02735 FSB76_30780
MRUBDEO27_005760 DEO27_010820
MGOSDIU38_002285 DIU38_011655 DIU38_013890
MMABHQ865_03460
MGIKGO620_004285
MDJLLH06_15955
AGDFRZ59_13320
OLIFKG96_15455 FKG96_24395
SBXCA265_15345
CMRCycma_1886
CAMUCA2015_1800
BBDBelba_3815
EVIEchvi_1439 Echvi_1847
ESTDN752_13360 DN752_22850
ECHIFKX85_06875 FKX85_08995
EMAIKZP23_07040 KZP23_09360
ALMAO498_00475 AO498_05075
MDAIPZ59_00950
SLISlin_4690 Slin_4949 Slin_5806 Slin_6563
SRDSD10_00445 SD10_22215 SD10_25210
SMONAWR27_16620 AWR27_16625 AWR27_22650
SPIRCWM47_02710 CWM47_15865 CWM47_23720 CWM47_26275
SPIKEXU85_01870 EXU85_20810 EXU85_22445 EXU85_32735
SPIBG8759_04845 G8759_27020 G8759_32295
STAEHNV11_09320 HNV11_19680
SRHOHH216_01220 HH216_07885
PSEZHME7025_00207 HME7025_00599
AANHG9X63_05975
ALENG9X62_00275 G9X62_04725 G9X62_05680
CHRWKA713_18580
RHOZGXP67_09115 GXP67_35085
DFEDfer_2494 Dfer_5724
DSNHWI92_09330 HWI92_09775
DYCNFI80_02955 NFI80_10510
LBYLbys_3311
RSIRunsl_0516 Runsl_3527 Runsl_4138 Runsl_4816
RUNDR864_02025 DR864_04755 DR864_08180 DR864_08775 DR864_28700
RUPDTQ70_06540 DTQ70_09130 DTQ70_15450 DTQ70_21955
EOLEmtol_1002 Emtol_1232 Emtol_2222 Emtol_3083
FAEFAES_0842 FAES_1054 FAES_2381 FAES_2795
FIBA6C57_11220 A6C57_24360
ALSDJ013_04515 DJ013_15115
MAQALAG90_19515 LAG90_19520
HSWHsw_1405
HYMN008_14610
HYPA0257_21565
HYZAXW84_12440
HNVDDQ68_07400
HYJFHG12_16415
HQIH9L05_14355
HRSHER32_01665
HTSHMJ29_14610
HTBMTX78_00705
PKOPKOR_01650
RUFTH63_14970
RTIDC20_05350
ADDHUW48_08360 HUW48_20680
ASWUHUW51_03455
MTTFtrac_0843
FBTD770_23805 D770_24095
CHKD4L85_02680 D4L85_12625 D4L85_28620
GFOGFO_1027
GRLLPB144_04725
GFLGRFL_2906
GRSC7S20_13090
FBRFBFL15_0127
FGLEM308_10765
RBIRB2501_02785 RB2501_05705 RB2501_05745
ZPRZPR_2442
FBCFB2170_04980 FB2170_10304
MARMYQ22_09250 YQ22_09280
MARTBTR34_09330 BTR34_09360 BTR34_13670
MARBCJ263_07190 CJ263_16900
MAREEJ994_10475 EJ994_12235 EJ994_12265
CAOCelal_1740 Celal_1746
CLYCelly_1667
CLHIX49_08170
CBALM667_06140 M667_06165
CBATM666_06085 M666_06110
KDIKrodi_1255
DOKMED134_09706(betA)
DDOI597_0709(fdhL)
DODDCS32_05720
ZGAZOBELLIA_1915 ZOBELLIA_1922 ZOBELLIA_2208
MRSMurru_1519 Murru_2278
MLTVC82_1545 VC82_1552 VC82_1980
MUTGVT53_05510 GVT53_12450 GVT53_18280 GVT53_18315
MAQILDL77_09800 LDL77_09835 LDL77_16835
SPONHME9304_01715
PTQP700755_001830
POMMED152_05190(betA)
PRNBW723_01820
POACW731_13180
PHALH9I45_11060
PLITK8354_10530
PBATJL193_08625
WINWPG_1744 WPG_1897
SYISB49_11280
LULLPB138_12920 LPB138_12960
SALTAO058_04335 AO058_14870
SMISLDL76_09365 LDL76_11620
AALGAREALGSMS7_01562 AREALGSMS7_01568 AREALGSMS7_03131
FEKC1H87_15470 C1H87_15485
AUEC5O00_04585
AQBD1818_06215
AQAD1815_01160
AQDD1816_00755
EMARD1013_02015 D1013_10290 D1013_17705
MUREQY75_13855 EQY75_13885
AFLAFHG64_18435
ANPFK178_05975
MESQC7H62_0617
GAAHX109_04645 HX109_10085
CAGGHYG79_07165 HYG79_07195
LPALLDL79_07765
SINHLS482_06890
ASAGFGM00_05335 FGM00_16375 FGM00_16405
FLGLV716_06580 LV716_06615
FLBLV704_07595 LV704_07630
SABUMBM09_07600 MBM09_15615
ZSPMQE36_03815
FBEFF125_17570
FBMMQE35_07720 MQE35_07730
CPRVCYPRO_1995
 » show all
Reference
1  [PMID:6038493]
  Authors
Hayano K, Fukui S
  Title
Purification and properties of 3-ketosucrose-forming enzyme from the cells of Agrobacterium tumefaciens.
  Journal
J Biol Chem 242:3655-72 (1967)
Reference
2  [PMID:838689]
  Authors
Nakamura LK, Tyler DD.
  Title
Induction of D-aldohexoside:cytochrome c oxidoreductase in Agrobacterium tumefaciens.
  Journal
J Bacteriol 129:830-5 (1977)
DOI:10.1128/jb.129.2.830-835.1977
Reference
3  [PMID:3818559]
  Authors
Takeuchi M, Ninomiya K, Kawabata K, Asano N, Kameda Y, Matsui K.
  Title
Purification and properties of glucoside 3-dehydrogenase from Flavobacterium saccharophilum.
  Journal
J Biochem 100:1049-55 (1986)
DOI:10.1093/oxfordjournals.jbchem.a121784
Reference
4  [PMID:2844746]
  Authors
Takeuchi M, Asano N, Kameda Y, Matsui K.
  Title
Physiological role of glucoside 3-dehydrogenase and cytochrome c551 in the sugar oxidizing system of Flavobacterium saccharophilum.
  Journal
J Biochem 103:938-43 (1988)
DOI:10.1093/oxfordjournals.jbchem.a122390
Reference
5  [PMID:8984902]
  Authors
Tsugawa W, Horiuchi S, Tanaka M, Wake H, Sode K.
  Title
Purification of a marine bacterial glucose dehydrogenase from Cytophaga marinoflava and its application for measurement of 1,5-anhydro-D-glucitol.
  Journal
Appl Biochem Biotechnol 56:301-10 (1996)
DOI:10.1007/BF02786960
Reference
6  [PMID:11263965]
  Authors
Kojima K, Tsugawa W, Sode K.
  Title
Cloning and expression of glucose 3-dehydrogenase from Halomonas sp. alpha-15 in Escherichia coli.
  Journal
Biochem Biophys Res Commun 282:21-7 (2001)
DOI:10.1006/bbrc.2001.4511
Reference
7  [PMID:16292530]
  Authors
Zhang JF, Zheng YG, Xue YP, Shen YC.
  Title
Purification and characterization of the glucoside 3-dehydrogenase produced by a newly isolated Stenotrophomonas maltrophilia CCTCC M 204024.
  Journal
Appl Microbiol Biotechnol 71:638-45 (2006)
DOI:10.1007/s00253-005-0201-9
Reference
8  [PMID:28044272]
  Authors
Zhang JF, Chen WQ, Chen H.
  Title
Gene cloning and expression of a glucoside 3-dehydrogenase from Sphingobacterium faecium ZJF-D6, and used it to produce N-p-nitrophenyl-3-ketovalidamine.
  Journal
World J Microbiol Biotechnol 33:21 (2017)
DOI:10.1007/s11274-016-2187-0
  Sequence
Reference
9  [PMID:29625423]
  Authors
Miyazaki R, Yamazaki T, Yoshimatsu K, Kojima K, Asano R, Sode K, Tsugawa W.
  Title
Elucidation of the intra- and inter-molecular electron transfer pathways of glucoside 3-dehydrogenase.
  Journal
Bioelectrochemistry 122:115-122 (2018)
DOI:10.1016/j.bioelechem.2018.03.001
  Sequence
[atu:Atu4377]
Other DBs
ExplorEnz - The Enzyme Database: 1.1.2.11
IUBMB Enzyme Nomenclature: 1.1.2.11
ExPASy - ENZYME nomenclature database: 1.1.2.11
BRENDA, the Enzyme Database: 1.1.2.11
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