Entry Name Methanosarcina-phenazine hydrogenase;
Class Oxidoreductases;BRITE hierarchy
Sysname hydrogen:2-(2,3-dihydropentaprenyloxy)phenazine oxidoreductase
Reaction(IUBMB) H2 + 2-(2,3-dihydropentaprenyloxy)phenazine = 2-dihydropentaprenyloxyphenazine [RN:
R09095 ]
Reaction(KEGG) Substrate H2 [CPD:
C00282 ];
2-(2,3-dihydropentaprenyloxy)phenazine [CPD:
C11903 ]
Product 2-dihydropentaprenyloxyphenazine
Comment Contains nickel, iron-sulfur clusters and cytochrome b. The enzyme from some sources contains selenocysteine.
History EC 1.12.98.3 created 2002
Orthology K14068 methanophenazine hydrogenase, large subunit
K14069 methanophenazine hydrogenase, cytochrome b subunit
K14070 methanophenazine hydrogenase
Genes AVE : Arcve_0139 Arcve_1314
MBA : Mbar_A1839 Mbar_A1840 Mbar_A1841 Mbar_A1845 Mbar_A1846 Mbar_A1847
MBY : MSBRM_2559 MSBRM_2560 MSBRM_2561 MSBRM_2565 MSBRM_2566 MSBRM_2567
MBW : MSBRW_2889 MSBRW_2890 MSBRW_2891 MSBRW_2894 MSBRW_2895 MSBRW_2896
MBAR : MSBR2_2533 MSBR2_2534 MSBR2_2535 MSBR2_2539 MSBR2_2540 MSBR2_2541
MBAK : MSBR3_2555 MSBR3_2556 MSBR3_2557 MSBR3_2562 MSBR3_2563 MSBR3_2564
MAC : MA_1141(vhtG) MA_1142(vhtA) MA_1143(vhtC) MA_1146(vhtG) MA_1147(vhtA) MA_1148(vhtC)
MMA : MM_2169(vhtG) MM_2170(vhtA) MM_2171(vhtC) MM_2175 MM_2176 MM_2177 MM_2312(vhoC) MM_2313(vhoA) MM_2314(vhoG)
MMAZ : MmTuc01_2221 MmTuc01_2222 MmTuc01_2223 MmTuc01_2227 MmTuc01_2228 MmTuc01_2229 MmTuc01_2361
MMJ : MSMAS_2387 MSMAS_2388 MSMAS_2389 MSMAS_2512 MSMAS_2513 MSMAS_2514 MSMAS_2518 MSMAS_2519 MSMAS_2520
MMAC : MSMAC_1925 MSMAC_1926 MSMAC_1927 MSMAC_1931 MSMAC_1932 MSMAC_1933 MSMAC_2057 MSMAC_2058 MSMAC_2059
MVC : MSVAZ_2597 MSVAZ_2598 MSVAZ_2599 MSVAZ_2603 MSVAZ_2604 MSVAZ_2605
MEK : MSKOL_2601 MSKOL_2602 MSKOL_2603 MSKOL_2607 MSKOL_2608 MSKOL_2609
MLS : MSLAZ_0687 MSLAZ_0689 MSLAZ_0690 MSLAZ_0691 MSLAZ_1004 MSLAZ_1005 MSLAZ_1006
METM : MSMTP_2424 MSMTP_2425 MSMTP_2426 MSMTP_2429 MSMTP_2430 MSMTP_2431
MEF : MSWH1_2363 MSWH1_2364 MSWH1_2365 MSWH1_2368 MSWH1_2369 MSWH1_2370
MEQ : MSWHS_2735 MSWHS_2736 MSWHS_2737 MSWHS_2740 MSWHS_2741 MSWHS_2742
MSJ : MSSAC_3200 MSSAC_3201 MSSAC_3202 MSSAC_3205 MSSAC_3206 MSSAC_3207
MSZ : MSSIH_1030 MSSIH_1031 MSSIH_1032 MSSIH_1035 MSSIH_1036 MSSIH_1037
MSW : MSSIT_1077 MSSIT_1078 MSSIT_1079 MSSIT_1082 MSSIT_1083 MSSIT_1084
MTHR : MSTHT_1112 MSTHT_1113 MSTHT_1114 MSTHT_1117 MSTHT_1118 MSTHT_1119
MTHE : MSTHC_2184 MSTHC_2185 MSTHC_2186 MSTHC_2189 MSTHC_2190 MSTHC_2191
MHOR : MSHOH_3149 MSHOH_3150 MSHOH_3151 MSHOH_3154 MSHOH_3155 MSHOH_3156
MFZ : AOB57_010820 AOB57_010825 AOB57_010830 AOB57_010845 AOB57_010850 AOB57_010855
MMET : MCMEM_1333 MCMEM_1334
MELO : J7W08_05350 J7W08_05355
MZH : Mzhil_0914 Mzhil_0915
MSEB : RE474_00065 RE474_00070 RE474_00075
MEHF : MmiHf6_04130 MmiHf6_04140(hybC) MmiHf6_04150
MEES : MmiEs2_06850 MmiEs2_06860(hydB) MmiEs2_06870
MPD : MCP_2934(vhtG) MCP_2935(vhtA) MCP_2936(vhtC)
MEZ : Mtc_0470(vhtG) Mtc_0471(vhtA) Mtc_0472(vhtC)
RCI : RCIX880(vhtG) RCIX882(vhtA) RCIX885(vhtC)
MEAM : MU439_03135 MU439_03140 MU439_03145
MEAE : QEN48_07220 QEN48_07225 QEN48_07230
» show all Taxonomy Reference Authors Abken HJ, Tietze M, Brodersen J, Baumer S, Beifuss U, Deppenmeier U.
Title Isolation and characterization of methanophenazine and function of phenazines in membrane-bound electron transport of Methanosarcina mazei Go1.
Journal Reference Authors Deppenmeier U, Lienard T, Gottschalk G.
Title Novel reactions involved in energy conservation by methanogenic archaea.
Journal Reference Authors Beifuss U, Tietze M, Baumer S, Deppenmeier U.
Title Methanophenazine: Structure, Total Synthesis, and Function of a New Cofactor from Methanogenic Archaea This work was supported by the Deutsche Forschungsgemeinschaft (Sonderforschungsbereich 416; grants De 488/6-1 and De 488/4-2) and the Fonds der Chemischen Industrie. We are grateful to Drs. J. Paust and H. Jaedicke (BASF AG, Ludwigshafen) and Dr. R. K. Muller (Hoffmann-La Roche Ltd., Basel) for generously providing chemicals.
Journal Other DBs ExPASy - ENZYME nomenclature database: 1.12.98.3
LinkDB All DBs
