| Entry |
|
|---|
| Name |
2-amino-1-hydroxyethylphosphonate dioxygenase (glycine-forming);
phnZ (gene name)
|
|---|
| Class |
Oxidoreductases;
Acting on single donors with incorporation of molecular oxygen (oxygenases);
With incorporation of two atoms of oxygen
|
|---|
| Sysname |
2-amino-1-hydroxyethylphosphonate:oxygen 1-oxidoreductase (glycine-forming)
|
|---|
| Reaction(IUBMB) |
(2-amino-1-hydroxyethyl)phosphonate + O2 = glycine + phosphate [RN: R10722]
|
|---|
| Reaction(KEGG) |
|
|---|
| Substrate |
(2-amino-1-hydroxyethyl)phosphonate [CPD: C05678];
O2 [CPD: C00007]
|
|---|
| Product |
|
|---|
| Comment |
Requires Fe2+. The enzyme, characterized from a marine bacterium, is involved in a 2-aminoethylphosphonate degradation pathway.
|
|---|
| History |
EC 1.13.11.78 created 2014
|
|---|
| Pathway |
| ec00440 | Phosphonate and phosphinate metabolism |
|
|---|
| Orthology |
| K05915 | (hydroxymethyl)phosphonate/2-amino-1-hydroxyethylphosphonate dioxygenase |
| K21196 | 2-amino-1-hydroxyethylphosphonate dioxygenase (glycine-forming) |
|
|---|
| Genes |
» show all
|
|---|
| Reference |
|
|---|
| Authors |
McSorley FR, Wyatt PB, Martinez A, DeLong EF, Hove-Jensen B, Zechel DL |
|---|
| Title |
PhnY and PhnZ comprise a new oxidative pathway for enzymatic cleavage of a carbon-phosphorus bond. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Worsdorfer B, Lingaraju M, Yennawar NH, Boal AK, Krebs C, Bollinger JM Jr, Pandelia ME |
|---|
| Title |
Organophosphonate-degrading PhnZ reveals an emerging family of HD domain mixed-valent diiron oxygenases. |
|---|
| Journal |
|
|---|
| Sequence |
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
