EC 22.214.171.124 Enzyme
dissimilatory dimethyl sulfide monooxygenase;
dmoAB (gene names);
dimethyl sulfide C-monooxygenase;
dimethylsulfide monooxygenase (ambiguous);
dimethyl sulfide monooxygenase (ambiguous)
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
dimethyl sulfide,NADH:oxygen oxidoreductase
dimethyl sulfide + O2 + NADH + H+ = methanethiol + formaldehyde + NAD+ + H2O [RN:
dimethyl sulfide [CPD:
The enzyme participates exclusively in sulfur dissimilation. It has lower activity with diethyl sulfide and other short-chain alkyl methyl sulfides. Its activity is stimulated by combined addition of FMN, and, after depletion of cations, of Mg2+ and Fe2+. The enzymes from bacteria of the Hyphomicrobium genus are a two component system that includes an FMN-dependent reductase subunit and a monooxygenase subunit.
EC 126.96.36.199 created 2011
De Bont, J.A.M., Van Dijken, J.P. and Harder, W.
Dimethyl sulphoxide and dimethyl sulphide as a carbon, sulphur and energy source for growth of Hyphomicrobium S.
J Gen Microbiol 127:315-323 (1981)
Boden R, Borodina E, Wood AP, Kelly DP, Murrell JC, Schafer H
Purification and characterization of dimethylsulfide monooxygenase from Hyphomicrobium sulfonivorans.
J Bacteriol 193:1250-8 (2011)
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