KEGG   ENZYME: 1.14.13.226
Entry
EC 1.14.13.226              Enzyme                                 
Name
acetone monooxygenase (methyl acetate-forming);
acmA (gene name)
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
Sysname
acetone,NADPH:oxygen oxidoreductase (methyl acetate-forming)
Reaction(IUBMB)
acetone + NADPH + H+ + O2 = methyl acetate + NADP+ + H2O [RN:R10704]
Reaction(KEGG)
R10704
Substrate
acetone [CPD:C00207];
NADPH [CPD:C00005];
H+ [CPD:C00080];
O2 [CPD:C00007]
Product
methyl acetate [CPD:C17530];
NADP+ [CPD:C00006];
H2O [CPD:C00001]
Comment
Contains FAD. The enzyme, characterized from the bacterium Gordonia sp. TY-5, is a Baeyer-Villiger type monooxygenase and participates in a propane utilization pathway.
History
EC 1.14.13.226 created 2016
Pathway
ec00650  Butanoate metabolism
ec01100  Metabolic pathways
Orthology
K18371  acetone monooxygenase (methyl acetate-forming)
Genes
GAIIMCC3135_04360(pamO)
MPTMpe_B0610
ATERMW290_07650
METRBSY238_2655(pamO)
AZQG3580_01435
BICLMTR13_14840
BRKCWS35_07445
BOTCIT37_15830
BELBE61_05150
BSEPHAP48_0013925
BQBJ4P68_0017965
MINDmvi_45310
MOGMMB17_17605
BIDBind_3904
RUTFIU92_22085(pamO)
DSHDshi_2283(pamO)
TOMBWR18_02365
SAGUCDO87_05620
THAACFI11_16920
HMLHmaOT1_18900
SROEJL101_032760
TMOTMO_c0213(pamO)
RHARHA1_ro08185 RHA1_ro10187
RPYY013_12765
RBYCEJ39_00255
RHQIM25_04320
GBRGbro_0088
GPOGPOL_c02620
GITC6V83_11880
GOMD7316_03881(pamO_3)
GPDGII33_00770
GOILK459_08565
NAQUENKNEFLB_03695
NMLNamu_3461
GOBGobs_1837
PAUTPdca_23100
PBROHOP40_31185
 » show all
Reference
1  [PMID:17071761]
  Authors
Kotani T, Yurimoto H, Kato N, Sakai Y
  Title
Novel acetone metabolism in a propane-utilizing bacterium, Gordonia sp. strain TY-5.
  Journal
J Bacteriol 189:886-93 (2007)
DOI:10.1128/JB.01054-06
Other DBs
ExplorEnz - The Enzyme Database: 1.14.13.226
IUBMB Enzyme Nomenclature: 1.14.13.226
ExPASy - ENZYME nomenclature database: 1.14.13.226
BRENDA, the Enzyme Database: 1.14.13.226
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