| Entry |
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| Name |
kynurenine 7,8-hydroxylase;
kynurenic acid hydroxylase;
kynurenic hydroxylase;
kynurenate 7,8-hydroxylase
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| Class |
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
Miscellaneous
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| Sysname |
kynurenate,hydrogen-donor:oxygen oxidoreductase (hydroxylating)
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| Reaction(IUBMB) |
kynurenate + reduced acceptor + O2 = 7,8-dihydro-7,8-dihydroxykynurenate + acceptor [RN: R03441]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
7,8-dihydro-7,8-dihydroxykynurenate [CPD: C01249];
acceptor [CPD: C00028]
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| History |
EC 1.14.99.2 created 1965 as EC 1.14.1.4, transferred 1972 to EC 1.14.99.2
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| Pathway |
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| Reference |
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| Authors |
TANIUCHI H, HAYAISHI O. |
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| Title |
Studies on the metabolism of kynurenic acid. III. Enzymatic formation of 7,8-dihydroxykynurenic acid from kynurenic acid. |
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| Journal |
J Biol Chem 238:283-93 (1963) |
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| Other DBs |
| ExPASy - ENZYME nomenclature database: | 1.14.99.2 |
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| LinkDB |
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