KEGG ENZYME: 1.14.99.48

ENZYME: 1.14.99.48

Entry

EC 1.14.99.48               Enzyme

Name

heme oxygenase (staphylobilin-producing);
haem oxygenase (ambiguous);
heme oxygenase (decyclizing) (ambiguous);
heme oxidase (ambiguous);
haem oxidase (ambiguous);
heme oxygenase (ambiguous);
isdG (gene name);
isdI (gene name)

Class

Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
Miscellaneous

Sysname

protoheme,hydrogen-donor:oxygen oxidoreductase (delta/beta-methene-oxidizing, hydroxylating)

Reaction(IUBMB)

(1) protoheme + 5 reduced acceptor + 4 O2 = beta-staphylobilin + Fe2+ + formaldehyde + 5 acceptor + 4 H2O [RN:R10468];
(2) protoheme + 5 reduced acceptor + 4 O2 = delta-staphylobilin + Fe2+ + formaldehyde + 5 acceptor + 4 H2O [RN:R10510]

Reaction(KEGG)

R10468 R10510

Substrate

protoheme [CPD:C00032];
reduced acceptor [CPD:C00030];
O2 [CPD:C00007]

Product

beta-staphylobilin [CPD:C20667];
Fe2+ [CPD:C14818];
formaldehyde [CPD:C00067];
acceptor [CPD:C00028];
H2O [CPD:C00001];
delta-staphylobilin [CPD:C20666]

Comment

This enzyme, which is found in some pathogenic bacteria, is involved in an iron acquisition system that catabolizes the host's hemoglobin. The two enzymes from the bacterium Staphylococcus aureus, encoded by the isdG and isdI genes, produce 67.5 % and 56.2 % delta-staphylobilin, respectively.

History

EC 1.14.99.48 created 2013

Pathway

ec00860

Porphyrin metabolism

ec01110

Biosynthesis of secondary metabolites

Orthology

K07145

heme oxygenase (staphylobilin-producing)

Genes

VIT:	ADP71_24520

VST:	LVJ81_01930

VMS:	LVJ82_12060

SDO:	SD1155_00595

BSU:	BSU07150(yetG)

BSR:

I33_0806

BSL:

A7A1_1759

BSH:	BSU6051_07150(yetG)

BSY:	I653_03610

BSUT:

BSUB_00788(hmoA)

BSUL:

BSUA_00788(hmoA)

BSUS:

Q433_04020

BSO:	BSNT_07101

BSN:	BSn5_15480

BSQ:	B657_07150(hmoA)

BSX:	C663_0743(yetG)

BSP:	U712_03610

BSS:	BSUW23_03645(yetG)

BST:

GYO_0975

BIT:	BIS30_14200

BAY:	RBAM_007300

BAQ:	BACAU_0699(yetG)

BYA:	BANAU_0651(yetG)

BAMP:

B938_03450

BQY:	MUS_0716(yetG)

BAML:

BAM5036_0649(hmoA)

BAMA:

RBAU_0713(hmoA)

BAMN:

BASU_0690(hmoA)

BAMB:

BAPNAU_0661(yetG)

BAMT:

AJ82_04065

BAMY:

V529_06760(yetG)

BMP:	NG74_00725(hmoA)

BAO:	BAMF_0686(yetG)

BAZ:	BAMTA208_03235(yetG)

BQL:	LL3_00735(yetG)

BXH:	BAXH7_00680(yetG)

BAMI:

KSO_016125

BAMC:

U471_07060

BAMF:

U722_03630

BSIA:

CWD84_18370

BAE:	BATR1942_01160

BVM:	B9C48_03645

BSON:

S101395_01740(isdG)

BHT:	DIC78_06215

BMOJ:

HC660_07630(hmoA)

BTEQ:

G4P54_03795(hmoA)

BIQ:	AN935_03760

BSTR:

QI003_03965(hmoA)

BAN:	BA_2987 BA_4782(isdG)

BAR:	GBAA_2987 GBAA_4782

BAT:	BAS2776 BAS4437

BAH:	BAMEG_1617 BAMEG_4814(isdG)

BAI:	BAA_3041 BAA_4795(isdG)

BAX:	H9401_2849 H9401_4564

BANT:

A16_30140 A16_47730

BANR:

A16R_30600 A16R_48410

BANS:

BAPAT_2864 BAPAT_4588

BANH:

HYU01_14770 HYU01_23305

BANV:

DJ46_1749 DJ46_3451(isdG)

BCE:	BC2969 BC4542

BCA:	BCE_3024 BCE_4666

BCZ:	BCE33L2706(yetG) BCE33L4287

BCR:	BCAH187_A3023 BCAH187_A4669(isdG)

BCB:	BCB4264_A2988 BCB4264_A4651(isdG)

BCU:	BCAH820_2983 BCAH820_4656(isdG)

BCG:	BCG9842_B0586(isdG) BCG9842_B2256

BCQ:	BCQ_2805(yetG) BCQ_4348

BCX:	BCA_3058 BCA_4648(isdG)

BAL:	BACI_c29410 BACI_c45330

BNC:	BCN_2829 BCN_4443

BCF:	bcf_14575 bcf_22735

BCER:

BCK_12535 BCK_19975

BCEF:

BcrFT9_02339

BCY:	Bcer98_2029

BTK:	BT9727_2725(yetG) BT9727_4276

BTL:	BALH_2673 BALH_4126

BTB:	BMB171_C2672 BMB171_C4187(isdG)

BTT:	HD73_3002 HD73_4836

BTHR:

YBT1520_14770 YBT1520_23995

BTHI:

BTK_14870 BTK_23835

BTC:	CT43_CH2970 CT43_CH4562(isdG)

BTF:	YBT020_14855 YBT020_22325

BTM:	MC28_2172 MC28_3822(isdG)

BTG:	BTB_c30980(yetG) BTB_c46910(isdG)

BTI:	BTG_04480 BTG_26165

BTN:	BTF1_12380 BTF1_21250

BTHT:

H175_ch3021 H175_ch4635

BTHU:

YBT1518_16415 YBT1518_25125

BTW:	BF38_295(isdG) BF38_4139

BTHY:

AQ980_07180 AQ980_16125

BWE:	BcerKBAB4_2781 BcerKBAB4_4370

BWW:	bwei_0354(isdG) bwei_2040

BMYO:

BG05_1501(isdG) BG05_3039

BTY:	Btoyo_0267 Btoyo_1780

BMYC:

DJ92_71

BBY:	CY96_13690 CY96_21850

BWD:	CT694_15945 CT694_24270

BTRO:

FJR70_04240 FJR70_16455(isdG)

BMOB:

MLA2C4_15715 MLA2C4_23605

BNT:	GSN03_14395 GSN03_21575

BPAC:

LMD38_04210(isdG) LMD38_12180(hmoA)

BPAN:

NLJ82_14005(hmoA) NLJ82_22225(isdG)

BALU:

QRY64_16990(hmoA) QRY64_25600(isdG)

BIF:	N288_04365

BWH:	A9C19_20435

BCAB:

EFK13_04130(hmoA)

BRY:	M0696_04110(hmoA)

BJS:

MY9_0807

GST:	HW35_12025

BACP:

SB24_06200

BACB:

OY17_06315

BACO:

OXB_2435

BACY:

QF06_02480

BACL:

BS34A_08140(yetG)

BALM:

BsLM_0754

BACS:

AUL54_07150

BACQ:

DOE78_03345

BZH:	NF868_16190

BCAO:

LC087_11600

BARD:

QRY57_15020

BCO:	Bcell_0394 Bcell_1360

BCOH:

BC6307_02495 BC6307_08775

BCIR:

C2I06_18370

NTX:	NQZ71_12910 NQZ71_16890

NIL:	L8T27_005085 L8T27_008955

PKS:	IE339_13780 IE339_16400

BHA:	BH3293 BH3883

BKW:	BkAM31D_25155(hmoA)

BCL:	ABC1472 ABC1946 ABC3425

BLE:	BleG1_3399

SHUA:

PQ477_04645 PQ477_14950

BGI:	BGM20_18740

BPF:	BpOF4_08900(yetG) BpOF4_11030

BON:	A361_02340

BKO:	CKF48_02480 CKF48_11485 CKF48_17440

CSUA:

IM538_06905

CFIR:

NAF01_02335

CSOA:

LIS82_19825

CSPG:

LS684_19930

CPSS:

M5V91_19855

OCN:	CUC15_03770

OCB:	CV093_03880

GTM:	GT3921_04975 GT3921_15985

GLI:	GLN3_13780

GCT:	GC56T3_2845

GMC:	GY4MC1_3571

GEJ:	A0V43_00950

GZA:	IC807_17130

GTH:	Geoth_3684

PTL:	AOT13_04560

AFL:

Aflv_2491

AGN:	AFK25_12830

ASED:

IRT44_16690

AAYD:

B379_08775

LSP:	Bsph_3066 Bsph_4360 Bsph_4673

LGY:	T479_21725 T479_23240

LFU:	HR49_00590 HR49_02385

LYS:	LBYS11_20915 LBYS11_22505

LYB:	C3943_24620 C3943_26455

LYZ:	DCE79_05315 DCE79_17140

LYG:	C1N55_18660

LPAK:

GDS87_22120 GDS87_23775

LAGR:

FJQ98_24045 FJQ98_25930

LMAC:

I6G82_19470 I6G82_21435

LYC:	FH508_0021980 FH508_0023325

LCAP:

ICJ70_00925 ICJ70_02875

LYP:	MTP04_35780(hmoA)

LIU:	OU989_20350 OU989_21955

LLB:	R6U77_07350 R6U77_07380

HSAN:

MUN89_11475

TAP:	GZ22_12845

VIR:	X953_07825

VHL:	BME96_06720

VIG:	BKP57_15785

VPN:	A21D_01200(isdG)

VIK:	KFZ58_07785

APAK:

AP3564_01100 AP3564_01135

ACOP:

RI196_16445 RI196_16515

BSJ:	UP17_24860

BMUR:

ABE28_003985 ABE28_023625

PBUT:

DTO10_11530

PASA:

BAOM_5089(isdG)

PPSR:

I6J18_13400 I6J18_14750

PFRI:

L8956_04465 L8956_26355

PERI:

RE409_27525

PSYH:

D0S48_12670 D0S48_20300

PSYO:

PB01_20345 PB01_20455

PSYB:

KD050_08565

PRD:	F7984_11975 F7984_16060

SCIA:

HUG15_08160

NDT:	L1999_14880

MLIT:

KDJ21_008435

MENL:

MVE64_10330 MVE64_21475

MEBZ:

LPC09_07575

BLEN:

NCTC4824_03741(isdI)

RAZ:	U9J35_02960

ROSS:

V2W31_03000

BAG:

Bcoa_2560

BOU:	I5818_11645

BBEV:

BBEV_2100

BSE:

Bsel_2560

SLMS:

MM221_02285 MM221_11730

MJO:	FOF60_03680

FHL:	OE105_02135

FAF:	OE104_09005

ECTO:

MUG87_15600

ALKL:

MM271_02645 MM271_15145

PHJ:	LC071_14680

DOM:	RRU94_04490 RRU94_11400

AHAL:

FTX54_006045

SAU:	SA0160 SA0983(isdG)

SAV:	SAV0165 SAV1136

SAW:	SAHV_0164 SAHV_1127

SAH:	SaurJH1_0156 SaurJH1_1217

SAJ:	SaurJH9_0151 SaurJH9_1195

SAM:	MW0140 MW1018(isdG)

SAS:	SAS0140 SAS1070

SAR:	SAR0167 SAR1109

SAC:	SACOL0152 SACOL1146

SAX:	USA300HOU_0179(isdG1) USA300HOU_1069(isdG2)

SAA:	SAUSA300_0168 SAUSA300_1035

SAO:	SAOUHSC_00130 SAOUHSC_01089

SAE:	NWMN_0111 NWMN_1047(isdG)

SAD:	SAAV_0133 SAAV_1102

SUU:	M013TW_0155(isdI) M013TW_1069(isdG)

SUV:	SAVC_00595 SAVC_04845

SUE:	SAOV_0112 SAOV_1132

SUJ:	SAA6159_00149(isdI) SAA6159_00990(isdG)

SUK:	SAA6008_00143(isdI) SAA6008_01090(isdG)

SUC:	ECTR2_129 ECTR2_990

SUT:	SAT0131_00156 SAT0131_01176

SUQ:	HMPREF0772_10333(isdI) HMPREF0772_12097(isdG)

SUZ:	MS7_0159(isdI) MS7_1092(isdG)

SUD:	ST398NM01_0179 ST398NM01_1132

SUX:	SAEMRSA15_01310 SAEMRSA15_09650

SUW:	SATW20_01760(isdI) SATW20_11300(isdG)

SUG:	SAPIG0179 SAPIG1132

SUF:	SARLGA251_01390(isdI) SARLGA251_10480(isdG)

SAUA:

SAAG_00648 SAAG_02244

SAUE:

RSAU_000119(isdI) RSAU_001020(isdG)

SAUN:

SAKOR_00145 SAKOR_01057

SAUS:

SA40_0132(isdI) SA40_1006(isdG)

SAUU:

SA957_0147(isdI) SA957_1021(isdG)

SAUG:

SA268_0144(isdI) SA268_1024(isdG)

SAUZ:

SAZ172_0175 SAZ172_1135(isdI)

SAUF:

X998_0148(isdI) X998_1133(isdG)

SAB:

SAB1000

SUY:	SA2981_0166(isdI) SA2981_1092(isdG)

SAUB:

C248_0154 C248_1162

SAUM:

BN843_10400 BN843_1710

SAUC:

CA347_1050(isdI) CA347_177(isdI)

SAUR:

SABB_00362(isdG) SABB_01676(isdI)

SAUI:

AZ30_00865 AZ30_05430

SAUD:

CH52_00210 CH52_04900

SAMS:

NI36_00760 NI36_05470

SUH:	SAMSHR1132_01390 SAMSHR1132_09820

SER:

SERP1773

SEP:

SE_1764

SEPP:

SEB_01773

SEPS:

DP17_717

SHA:

SH0867

SHH:	ShL2_00760(isdI)

SSP:

SSP0713

SCA:	SCA_0030 SCA_1676

SLG:	SLGD_00072 SLGD_00101

SLN:	SLUG_01000(isdG)

SSD:	SPSINT_2202

SDT:	SPSE_0265(isdI)

SDP:	NCTC12225_00319(isdI)

SWA:	A284_03620

SPAS:

STP1_0602(isdG)

SXY:	BE24_08420

SXL:	SXYLSMQ121_0745

SXO:	SXYL_00755(isdG)

SHU:	SHYC_11695(isdI)

SCAP:

AYP1020_0461(isdG) AYP1020_1366(isdI)

SSCH:

LH95_01615

SSCZ:

RN70_01955

SAGQ:

EP23_10475

SEQO:

SE1039_18640

SSIF:

AL483_01460 AL483_06750

SCV:	A4G25_07625 A4G25_11745

SPET:

CEP67_04900 CEP67_09800

SLZ:	B5P37_04670

SCOH:

BZ166_07990

SURY:

MUA21_09170

SNL:	BJD96_03890

SKL:	C7J89_05070

SFQ:	C7J90_04415

SHOM:

EGX58_07775

SCAR:

DWB96_03785 DWB96_08955

SCHR:

DWB92_11750

SARL:

SAP2_07790(isdG)

SPIC:

SAMEA4384060_0856(isdI)

SSH:	NCTC13712_00120(isdI) NCTC13712_01080(isdG)

SDB:	CNQ82_10340

SLLO:

ISP08_03735

SAUL:

I6G39_09720

SSAC:

I6I31_00895

SRAI:

LN051_11000

SPSD:

JMB28_04225

STAS:

HYI43_04075

SEDA:

MNY58_03790

SCAQ:

QMO72_03735

SDEV:

Q2T90_03585 Q2T90_07335

SROT:

ML435_00655(isdI) ML435_05185(isdG)

STAP:

AOB58_2571

SHSI:

QQM35_00590

SSCU:

CEP64_00990 CEP64_01350

SFF:	FOB90_06180

SSTE:

SAMEA4384403_0335(isdG)

MLEN:

H3V22_06945 H3V22_07340

MVT:	I6J10_09370

MACR:

BHM04_08380

MARY:

LAU42_01910

MBRU:

MGG13_02205

MEPI:

KFV12_02495

MEQU:

KFV11_01900

MBOC:

QSV55_02205

MCL:

MCCL_0304

MCAK:

MCCS_04680(isdG)

MBOE:

HT586_02430

SHV:	AAT16_00590

LMO:

lmo0484

LMN:	LM5578_0507

LMY:	LM5923_0506

LMT:	LMRG_00165

LMOC:

LMOSLCC5850_0477

LMOE:

BN418_0554

LMOB:

BN419_0559

LMOD:

LMON_0484

LMOW:

AX10_10940

LMOQ:

LM6179_00783(isdG)

LMR:	LMR479A_0491(isdG)

LMOM:

IJ09_07955

LMF:	LMOf2365_0511

LMC:	Lm4b_00504

LMOG:

BN389_05190(isdG)

LMP:

MUO_02665

LMOL:

LMOL312_0486

LMOJ:

LM220_06802

LMOZ:

LM1816_10672(isdG)

LMOX:

AX24_15315

LMH:	LMHCC_2158

LMQ:	LMM7_0504(isdG)

LML:	lmo4a_0489

LMG:	LMKG_01417

LMS:

LMLG_2751

LMJ:	LMOG_02285

LMW:	LMOSLCC2755_0482

LMX:	LMOSLCC2372_0492

LMZ:	LMOSLCC2482_0478

LMON:

LMOSLCC2376_0465

LMOS:

LMOSLCC7179_0457

LMOO:

LMOSLCC2378_0506

LMOY:

LMOSLCC2479_0491

LMOT:

LMOSLCC2540_0489

LMOA:

LMOATCC19117_0511

LMOK:

CQ02_02645

LMV:	Y193_13320(isdG)

LIN:

lin0487

LWE:

lwe0452

LSG:

lse_0393

LIV:

LIV_0383

LII:	JL52_02250

LIW:	AX25_02300

LIA:	JL58_02320

LIO:	JL53_02630

LGZ:	NCTC10812_00640(isdG)

LMAR:

LAX80_002200(isdG)

BTHS:

CNY62_04265

ESI:	Exig_1574 Exig_2978

EAT:	EAT1b_1853

EAN:	Eab7_1452 Eab7_2788

EXM:	U719_06025 U719_08705 U719_16210

EXU:	ESP131_01830 ESP131_10790

EAP:	KB235_01020

EACE:

KKI46_08595 KKI46_16075

EAUR:

NMQ00_15160

EMM:	PTI97_00420

EPF:	OE059_14400

EXI:	A0126_05855 A0126_07780 A0126_14560 A0126_18060

EXH:	HNY42_00915 HNY42_07465 HNY42_09705

BBE:	BBR47_55400

BLR:	BRLA_c025910(hmoA)

BFM:	BP422_23370

BAGR:

BA6348_04585

BRW:	GOP56_05490

BCHS:

JNE38_22715

BPAB:

PSE45_26340

BHUI:

LOK74_22480

BAYD:

BSPP4475_08670

BBOR:

RFB14_19695

BRUM:

NDK47_20450

BREH:

HP435_26900

PJD:	Pjdr2_1740 Pjdr2_5714

GYM:	GYMC10_2490 GYMC10_6028

PPY:

PPE_04042

PPM:	PPSC2_21345(isdG)

PPO:	PPM_4254(isdG)

PPOL:

X809_37370

PPQ:	PPSQR21_043140

PPOY:

RE92_15910

PMS:	KNP414_04593 KNP414_07671

PMQ:	PM3016_7201

PMW:

B2K_36325

PTA:	HPL003_02775

PLV:	ERIC2_c04680 ERIC2_c36970

PSAB:

PSAB_22785

PDU:	PDUR_25720

PBD:	PBOR_16395 PBOR_34135

PGM:	PGRAT_30540

POD:	PODO_29020

PAEN:

P40081_16645 P40081_35465

PAEF:

R50345_29115

PAEQ:

R50912_32090

PSTE:

PSTEL_25545

PAEA:

R70723_14230

PAEE:

R70331_13695 R70331_22600

PAEH:

H70357_15740 H70357_33225

PAEJ:

H70737_28735

PBJ:	VN24_12485

PIH:	UB51_23290

PRI:

PRIO_6394

PSON:

JI735_06715

PPEO:

ABE82_21300

PNP:	IJ22_07840

POW:	IJ21_31410

PBV:	AR543_16015 AR543_21280

PSWU:

SY83_12315

PIB:	BBD41_02425 BBD41_15810

PCX:	LPB68_12905 LPB68_20995

PKB:	B4V02_04110

PAIH:

ASL14_16680

PVO:	PVOR_00360

PLW:	D5F53_17200 D5F53_31640

PLEN:

EIM92_05810

PLUT:

EI981_04000

PCHI:

PC41400_13760 PC41400_26280

PBK:	Back11_53110

PPRT:

ET464_05885

PRZ:	GZH47_21285

PLYC:

GXP70_25260

PSOP:

KP014_01355

PTRI:

KDC22_31100

PALO:

E6C60_2147 E6C60_3995

PCEL:

HUB94_13105 HUB94_26575

PTJ:	JRJ22_11670 JRJ22_27440

PALR:

HGI30_02855 HGI30_11610

PTHI:

NDS46_19535 NDS46_20230

PKA:	PQ456_13650 PQ456_18600

PUI:	PUW25_15000

PMAH:

PTQ21_19935

PDY:	QJQ58_01890 QJQ58_02460

PMAE:

LMZ02_10340 LMZ02_10555

PWN:	QNH46_08540 QNH46_20850

PSPN:

L1F29_29830 L1F29_31405

PPOG:

QPK24_14725

PHK:	SK066_09840 SK066_19690

PNK:	AASFL403_00475 AASFL403_05420

PPAB:

KET34_15890

PKP:	SK3146_00083(hmoA) SK3146_04304(isdG)

PGLU:

A3958_08050

PLZH:

C0638_12105

COHN:

KCTCHS21_04450 KCTCHS21_40840(isdG)

CCHL:

FPL14_01030 FPL14_15930

CHEB:

HH215_08055 HH215_10700 HH215_25200

COHL:

J4772_00350 J4772_15255

AFX:	JZ786_17525

ALIC:

GI364_05290

SIV:	SSIL_0376 SSIL_2825

SSIL:

SOLI23_04510 SOLI23_16930

SOB:	CSE16_05455 CSE16_19850

PKU:	AUO94_00980

PRT:	AUC31_10905

PLL:	I858_008175

PANA:

BBH88_03675

PDG:	BCM40_00610

PHC:	BBI08_11820

PMAR:

B0X71_18150

PPLA:

BBI15_11125

PFAE:

AJGP001_16750

PLX:	CW734_17510

PMAT:

BBI11_00290

PDEC:

H1Q58_15825

PGQ:	FK545_16750

PLAY:

DNR44_001150

PLIQ:

QWY22_09340

PSHE:

QWY16_02290

PSHX:

QWY21_02340

KUR:	ASO14_2756 ASO14_689 ASO14_969

KZO:	NCTC404_00637(isdI_1) NCTC404_02707(isdG) NCTC404_03056(isdI_2)

SPSY:

AZE41_20890

SURE:

SporoP32a_01985 SporoP32a_12550 SporoP32a_12910

SPOS:

DV702_00455

STRB:

QWT68_09120

SJT:	PGH26_02735 PGH26_02740

RST:	ATY39_05175 ATY39_15730

VIJ:	JNUCC6_13145 JNUCC6_16270

UTH:	DKZ56_02600 DKZ56_08620

KEB:	GXN75_11305

ESS:	ATZ33_06225

ASAN:

AWM72_03805

CML:	BN424_3514(isdG)

CDJ:	BFC22_01655

DMT:	DESME_06340

DAI:	Desaci_3127

DMI:	Desmer_2655

ROC:	HF520_02730

ERH:

ERH_0453

ERS:	K210_00215

ERI:	EEI45_07660

ERD:	G7062_02660

EIO:	H9L01_07045

EEH:	LLS04_05640

ERV:	MX850_11965

ACL:

ACL_0959

AOC:	Aocu_05200

AHK:	NCTC10172_00044

ABRA:

BN85311450

APAL:

BN85405740

AAXA:

NCTC10138_01404(isdG)

SFK:

KY5_6671c

SKA:	CP970_07275

ACIT:

HPK19_13845

RRD:	RradSPS_1219

RUB:	GBA63_09020

KBS:	EPA93_21140

KBB:	ccbrp13_45780

PBT:	ING2E5B_1869

PSAC:

PSM36_1783

HALM:

FCF25_01275

HTU:

Htur_4641

HXA:	Halxa_0670

WAR:	HYS32_01865

» show all

Reference

1 [PMID:20180905]

Authors

Reniere ML, Ukpabi GN, Harry SR, Stec DF, Krull R, Wright DW, Bachmann BO, Murphy ME, Skaar EP

Title

The IsdG-family of haem oxygenases degrades haem to a novel chromophore.

Journal

Mol Microbiol 75:1529-38 (2010)
DOI:10.1111/j.1365-2958.2010.07076.x

Sequence

[sau:SA0160]

Reference

2 [PMID:23600533]

Authors

Matsui T, Nambu S, Ono Y, Goulding CW, Tsumoto K, Ikeda-Saito M

Title

Heme degradation by Staphylococcus aureus IsdG and IsdI liberates formaldehyde rather than carbon monoxide.

Journal

Biochemistry 52:3025-7 (2013)
DOI:10.1021/bi400382p

Reference

3 [PMID:26534961]

Authors

Streit BR, Kant R, Tokmina-Lukaszewska M, Celis AI, Machovina MM, Skaar EP, Bothner B, DuBois JL

Title

Time-resolved Studies of IsdG Protein Identify Molecular Signposts along the Non-canonical Heme Oxygenase Pathway.

Journal

J Biol Chem 291:862-71 (2016)
DOI:10.1074/jbc.M115.666560

Other DBs

ExplorEnz - The Enzyme Database:

1.14.99.48

IUBMB Enzyme Nomenclature:

1.14.99.48

ExPASy - ENZYME nomenclature database:

1.14.99.48

BRENDA, the Enzyme Database:

1.14.99.48

LinkDB

DBGET integrated database retrieval system