Entry Name 4-hydroxybenzaldehyde dehydrogenase (NAD+);
Class Oxidoreductases;BRITE hierarchy
Sysname 4-hydroxybenzaldehyde:NAD+ oxidoreductase
Reaction(IUBMB) 4-hydroxybenzaldehyde + NAD+ + H2O = 4-hydroxybenzoate + NADH + 2 H+ [RN:
R01293 ]
Reaction(KEGG) Substrate Product Comment The bacterial enzyme (characterized from an unidentified denitrifying bacterium) is involved in an anaerobic toluene degradation pathway. The plant enzyme is involved in formation of 4-hydroxybenzoate, a cell wall-bound phenolic acid that plays a major role in plant defense against pathogens. cf. EC
1.2.1.96 , 4-hydroxybenzaldehyde dehydrogenase (NADP+).
History EC 1.2.1.64 created 2000, modified 2015
Pathway ec01120 Microbial metabolism in diverse environments
Reference Authors Bossert ID, Whited G, Gibson DT, Young LY.
Title Anaerobic oxidation of p-cresol mediated by a partially purified methylhydroxylase from a denitrifying bacterium.
Journal Reference Authors Sircar D, Mitra A
Title Evidence for p-hydroxybenzoate formation involving enzymatic phenylpropanoid side-chain cleavage in hairy roots of Daucus carota.
Journal Other DBs ExplorEnz - The Enzyme Database: 1.2.1.64
ExPASy - ENZYME nomenclature database: 1.2.1.64
UM-BBD (Biocatalysis/Biodegradation Database): 1.2.1.64
LinkDB All DBs
