KEGG   ENZYME: 1.2.1.7
Entry
EC 1.2.1.7                  Enzyme                                 
Name
benzaldehyde dehydrogenase (NADP+);
NADP+-linked benzaldehyde dehydrogenase;
benzaldehyde dehydrogenase (NADP+)
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
Sysname
benzaldehyde:NADP+ oxidoreductase
Reaction(IUBMB)
benzaldehyde + NADP+ + H2O = benzoate + NADPH + 2 H+ [RN:R01420]
Reaction(KEGG)
R01420;
(other) R01294 R05289 R05663 R05664 R07666
Substrate
benzaldehyde [CPD:C00261];
NADP+ [CPD:C00006];
H2O [CPD:C00001]
Product
benzoate [CPD:C00180];
NADPH [CPD:C00005];
H+ [CPD:C00080]
History
EC 1.2.1.7 created 1961
Pathway
ec00622  Xylene degradation
ec00623  Toluene degradation
ec00627  Aminobenzoate degradation
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Reference
1  [PMID:13108854]
  Authors
GUNSALUS CF, STANIER RY, GUNSALUS IC.
  Title
The enzymatic conversion of mandelic acid to benzoic acid. III. Fractionation and properties of the soluble enzymes.
  Journal
J Bacteriol 66:548-53 (1953)
DOI:10.1128/JB.66.5.548-553.1953
Reference
2  [PMID:4383635]
  Authors
Stachow CS, Stevenson IL, Day D.
  Title
Purification and properties of nicotinamide adenine dinucleotide phosphate-specific benzaldehyde dehydrogenase from Pseudomonas.
  Journal
J Biol Chem 242:5294-300 (1967)
Other DBs
ExplorEnz - The Enzyme Database: 1.2.1.7
IUBMB Enzyme Nomenclature: 1.2.1.7
ExPASy - ENZYME nomenclature database: 1.2.1.7
UM-BBD (Biocatalysis/Biodegradation Database): 1.2.1.7
BRENDA, the Enzyme Database: 1.2.1.7
CAS: 9028-89-1
LinkDB

KEGG   REACTION: R05664
Entry
R05664                      Reaction                               
Definition
3-Methylbenzaldehyde + NADP+ + H2O <=> m-Methylbenzoate + NADPH + H+
Equation
C07209 + C00006 + C00001 <=> C07211 + C00005 + C00080
Reaction class
RC00001  C00005_C00006
RC00075  C07209_C07211
Enzyme
1.2.1.7         1.2.1.28
Pathway
rn00622  Xylene degradation
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01220  Degradation of aromatic compounds
Module
M00537  Xylene degradation, xylene => methylbenzoate
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.7
     R05664  3-Methylbenzaldehyde + NADP+ + H2O <=> m-Methylbenzoate + NADPH + H+
    1.2.1.28
     R05664  3-Methylbenzaldehyde + NADP+ + H2O <=> m-Methylbenzoate + NADPH + H+
Orthology
K00141  benzaldehyde dehydrogenase (NAD) [EC:1.2.1.28]
LinkDB

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