KEGG   ENZYME: 1.2.3.4
Entry
EC 1.2.3.4                  Enzyme                                 
Name
oxalate oxidase;
aero-oxalo dehydrogenase;
oxalic acid oxidase
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With oxygen as acceptor
Sysname
oxalate:oxygen oxidoreductase
Reaction(IUBMB)
oxalate + O2 + 2 H+ = 2 CO2 + H2O2 [RN:R00273]
Reaction(KEGG)
R00273
Substrate
oxalate [CPD:C00209];
O2 [CPD:C00007];
H+ [CPD:C00080]
Product
CO2 [CPD:C00011];
H2O2 [CPD:C00027]
Comment
Contains Mn2+ as a cofactor. The enzyme is not a flavoprotein as had been thought [3].
History
EC 1.2.3.4 created 1961
Pathway
ec00630  Glyoxylate and dicarboxylate metabolism
Orthology
K28780  oxalate oxidase
Genes
BDI: 100838544 100841795
ATS: 109742583 109742584 109742585 109742586 109742616 109742620 109742622 109742628 109742630 109742636 109742640 109742641 141021458
TDC: 119276585 119276586 119276587 119286148 119286152 119287001 119289215 119293246 119294714 119294715 119294716 119359278
TAES: 100415844 100499179 123070399 123082075 123082397 123082399 123086333 123087210 123087213 123090749 123094288 123094289 123095765 123095767 123095768 123095769 123099411 123099413 123099418 123185149 543007 543321 543323 543498
TUA: 125528226 125528227 125535911 125551347 125553429
HVG: 123451021 123451023 123451024
LPER: 127293354 127293355 127293356 127311219 127348502
LRD: 124659748 124660553 124703938
Reference
1  [PMID:13250021]
  Authors
DATTA PK, MEEUSE BJ.
  Title
Moss oxalic acid oxidase-a flavoprotein.
  Journal
Biochim Biophys Acta 17:602-3 (1955)
DOI:10.1016/0006-3002(55)90436-4
Reference
2  [PMID:9143327]
  Authors
Kotsira VP, Clonis YD.
  Title
Oxalate oxidase from barley roots: purification to homogeneity and study of some molecular, catalytic, and binding properties.
  Journal
Arch Biochem Biophys 340:239-49 (1997)
DOI:10.1006/abbi.1997.9896
Reference
3  [PMID:10493928]
  Authors
Requena L, Bornemann S.
  Title
Barley (Hordeum vulgare) oxalate oxidase is a manganese-containing enzyme.
  Journal
Biochem J 343 Pt 1:185-90 (1999)
Other DBs
ExplorEnz - The Enzyme Database: 1.2.3.4
IUBMB Enzyme Nomenclature: 1.2.3.4
ExPASy - ENZYME nomenclature database: 1.2.3.4
BRENDA, the Enzyme Database: 1.2.3.4
CAS: 9031-79-2
LinkDB

KEGG   REACTION: R00273
Entry
R00273                      Reaction                               
Name
oxalate:oxygen oxidoreductase
Definition
Oxalate + Oxygen <=> Hydrogen peroxide + 2 CO2
Equation
C00209 + C00007 <=> C00027 + 2 C00011
Reaction class
RC02755  C00007_C00027
RC02802  C00011_C00209
Enzyme
1.2.3.4
Pathway
rn00630  Glyoxylate and dicarboxylate metabolism
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.3  With oxygen as acceptor
    1.2.3.4
     R00273  Oxalate + Oxygen <=> Hydrogen peroxide + 2 CO2
Orthology
K28780  oxalate oxidase [EC:1.2.3.4]
Other DBs
RHEA: 21883
LinkDB

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