KEGG   ENZYME: 1.2.3.7
Entry
EC 1.2.3.7                  Enzyme                                 
Name
indole-3-acetaldehyde oxidase;
indoleacetaldehyde oxidase;
IAAld oxidase;
AO1;
indole-3-acetaldehyde:oxygen oxidoreductase
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With oxygen as acceptor
Sysname
(indol-3-yl)acetaldehyde:oxygen oxidoreductase
Reaction(IUBMB)
(indol-3-yl)acetaldehyde + H2O + O2 = (indol-3-yl)acetate + H2O2 [RN:R02681]
Reaction(KEGG)
R02681
Substrate
(indol-3-yl)acetaldehyde;
H2O [CPD:C00001];
O2 [CPD:C00007]
Product
(indol-3-yl)acetate [CPD:C00954];
H2O2 [CPD:C00027]
Comment
A hemoprotein. This enzyme is an isoform of aldehyde oxidase (EC 1.2.3.1). It has a preference for aldehydes having an indole-ring structure as substrate [6,7]. It may play a role in plant hormone biosynthesis as its activity is higher in the auxin-overproducing mutant, super-root1, than in wild-type Arabidopsis thaliana [7]. While (indol-3-yl)acetaldehyde is the preferred substrate, it also oxidizes indole-3-carbaldehyde and acetaldehyde, but more slowly. The enzyme from maize contains FAD, iron and molybdenum [4].
History
EC 1.2.3.7 created 1984, modified 2004, modified 2006
Pathway
ec00380  Tryptophan metabolism
ec01100  Metabolic pathways
Orthology
K11817  indole-3-acetaldehyde oxidase
K22417  benzaldehyde dehydrogenase (NAD+) / indole-3-acetaldehyde oxidase
Genes
ATHAT1G04580(AO4) AT3G43600(AAO2) AT5G20960(AO1)
ALY9328289
CRB17884094 17900582
CSAT104738981 104762389 104770481 104780236 104790642
EUSEUTSA_v10006570mg EUTSA_v10012448mg
BRP103844240 103845621 103848036 103851392 103873635
BNA106347703 106371001 106371701 106376414 106402186 106406426 106410244 106421339 106425715
BOE106295510 106317854 106326884 106335357
RSZ108812376 108815136 108832706 108842248
THJ104799592 104799593
CSV101222350
VVI100255199
OSA4334382 4348072
DOSAOs03t0790900-01(Os03g0790900) Os10t0138100-01(Os10g0138100)
OBR102704964
BDI100822277 100822898 100836900
ATS109747740 109747741 109747742 109752661 109765340
TDC119303471 119303472 119303473 119303474 119303476 119303477 119312128 119312132 119345299
TAES123105337 123105340 123105341 123105342 123105343 123105344 123113606 123113607 123113609 123123127 123123129 123123132 123123133
SBI8084125 8084128
ZMA103644157 542228 542229
SITA101754702 101755113 101764191
SVS117838077 117838078 117839666
PVIR120649504 120649505 120691959 120693301
PHAI112878335
 » show all
Reference
1  [PMID:16660220]
  Authors
Bower PJ, Brown HM, Purves WK.
  Title
Cucumber Seedling Indoleacetaldehyde Oxidase.
  Journal
Plant Physiol 61:107-110 (1978)
DOI:10.1104/pp.61.1.107
Reference
2
  Authors
Miyata, S., Suzuki, Y., Kamisaka, S. and Masuda, Y.
  Title
Indole-3-acetaldehyde oxidase of pea-seedlings.
  Journal
Physiol Plant 51:402-406 (1981)
Reference
3
  Authors
Rajagopal, R.
  Title
Metabolism of indole-3-acetaldehyde. III. Some characteristics of the aldehyde oxidase of Avena coleoptiles.
  Journal
Physiol Plant 24:272-281 (1971)
Reference
4  [PMID:12226218]
  Authors
Koshiba T, Saito E, Ono N, Yamamoto N, Sato M
  Title
Purification and Properties of Flavin- and Molybdenum-Containing Aldehyde Oxidase from Coleoptiles of Maize.
  Journal
Plant Physiol 110:781-789 (1996)
DOI:10.1104/pp.110.3.781
  Sequence
[zma:542228]
Reference
5  [PMID:12231908]
  Authors
Koshiba T, Matsuyama H.
  Title
An in Vitro System of Indole-3-Acetic Acid Formation from Tryptophan in Maize (Zea mays) Coleoptile Extracts.
  Journal
Plant Physiol 102:1319-1324 (1993)
DOI:10.1104/pp.102.4.1319
Reference
6  [PMID:9615466]
  Authors
Sekimoto H, Seo M, Kawakami N, Komano T, Desloire S, Liotenberg S, Marion-Poll A, Caboche M, Kamiya Y, Koshiba T
  Title
Molecular cloning and characterization of aldehyde oxidases in Arabidopsis thaliana.
  Journal
Plant Cell Physiol 39:433-42 (1998)
DOI:10.1093/oxfordjournals.pcp.a029387
  Sequence
Reference
7  [PMID:9489015]
  Authors
Seo M, Akaba S, Oritani T, Delarue M, Bellini C, Caboche M, Koshiba T.
  Title
Higher activity of an aldehyde oxidase in the auxin-overproducing superroot1 mutant of Arabidopsis thaliana.
  Journal
Plant Physiol 116:687-93 (1998)
DOI:10.1104/pp.116.2.687
  Sequence
[ath:AT5G20960]
Other DBs
ExplorEnz - The Enzyme Database: 1.2.3.7
IUBMB Enzyme Nomenclature: 1.2.3.7
ExPASy - ENZYME nomenclature database: 1.2.3.7
BRENDA, the Enzyme Database: 1.2.3.7
CAS: 66082-22-2
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