KEGG   ENZYME: 1.3.1.111
Entry
EC 1.3.1.111                Enzyme                                 
Name
geranylgeranyl-bacteriochlorophyllide a reductase;
geranylgeranyl-bacteriopheophytin reductase;
bchP (gene name)
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
bacteriochlorophyll-a:NADP+ oxidoreductase (geranylgeranyl-reducing)
Reaction(IUBMB)
bacteriochlorophyll a + 3 NADP+ = geranylgeranyl bacteriochlorophyllide a + 3 NADPH + 3 H+ [RN:R11226]
Reaction(KEGG)
R11226;
(other) R11518
Substrate
bacteriochlorophyll a [CPD:C11242];
NADP+ [CPD:C00006]
Product
geranylgeranyl bacteriochlorophyllide a [CPD:C21217];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
The enzyme catalyses the successive reduction of the geranylgeraniol esterifying group to phytol, reducing three out of four double bonds, and transforming geranylgeranyl bacteriochlorophyllide a via dihydrogeranylgeranyl bacteriochlorophyllide a and tetrahydrogeranylgeranyl bacteriochlorophyllide a to bacteriochlorophyll a. The enzyme can also accept the pheophytin derivative geranylgeranyl bacteriopheophytin, converting it to bacteriopheophytin a.
History
EC 1.3.1.111 created 2016
Pathway
ec00860  Porphyrin metabolism
ec01110  Biosynthesis of secondary metabolites
Orthology
K10960  geranylgeranyl diphosphate/geranylgeranyl-bacteriochlorophyllide a reductase
Genes
ATH: AT1G74470
ALY: 9325042
CRB: 17894023
CSAT: 104702172 104713087 104751317
EUS: EUTSA_v10018504mg
BRP: 103831923 103852907
BNA: 106354395 106381375 106405742 106430268
BOE: 106300254 106327384
RSZ: 108816096 108818449
THJ: 104813881
CPAP: 110806885 110823599
CIT: 102606922 102628832
CIC: CICLE_v10015206mg CICLE_v10020061mg
PVY: 116122320 116134344
MINC: 123204610 123212206
TCC: 18590126 18604703
GRA: 105788420 105799295
GHI: 107890070 107891506 107897682 107949818
GAB: 108457350 108483290
HSYR: 120142800 120158728 120168859
DZI: 111286751 111290004 111317484
EGR: 104419806 104433929
GMX: 100779933 100787525 100814603
GSJ: 114392628 114400616 114411854
PVU: PHAVU_003G189600g PHAVU_008G208000g
VRA: 106764806 106768993
VAR: 108323777 108338269
VUN: 114178019 114195668
VUM: 124826967
CCAJ: 109808310 109808821
APRC: 113846755 113847511
MTR: 11429848 120580108
TPRA: 123884252 123921785
CAM: 101494746 101504312
PSAT: 127073792 127117929
VVO: 131615961 131635191
LJA: 130710804 130733378
ADU: 107468034 107492652 107496713
AIP: 107608565 107633107
AHF: 112702176 112710187 112722504 112762670
LANG: 109344115 109353463 109360295 109362259
PCIN: 129318012 129320891
QSA: O6P43_001962 O6P43_013942 O6P43_020843 O6P43_022855
FVE: 101303515 101305804
RCN: 112179713 112181866
PPER: 18772334 18776056
PMUM: 103338504
PAVI: 110762352 110766036
PDUL: 117627412 117631371
MDM: 103424544 103437824 103441948
MSYL: 126591304 126598918 126625843
PXB: 103931434
ZJU: 107410339 107419241
MNT: 21399031 21405360
CSAV: 115709045 115718586
CSV: 101221755 105435233
CMO: 103491620 103493994(GGPR)
BHJ: 120071403 120088075
CMAX: 111471190 111483717 111484810
CMOS: 111429842 111440944 111448779
CPEP: 111777177 111779576 111793372 111793523
RCU: 8263422 8268692
MEAN: 126672828 126673288
JCU: 105629331 105640543
HBR: 110650769 110655700 110655724
MESC: 110599909
POP: 18098056 7460095 7484745
PEU: 105112328 105112893
PALZ: 118029001 118032400 118038976
PNZ: 133675214 133678089 133679837 133699886
JRE: 108995457 109018163
CILL: 122281679 122281811
CAVE: 132164172 132176034
QSU: 111998707 112033070
QLO: 115963881 115986518
TWL: 119990626 120009962
VVI: 100243277 100253115
VRI: 117904575 117915532
SLY: 101262299 101266160
SPEN: 107012756 107014180
SOT: 102598599 102599900
SSTN: 125853391 125857621
SDUL: 129884876 129896300
CANN: 107854916 107862250
LBB: 132632936 132644837
NTA: 107769989 107783257(chlP) 107803012 107830453(GGR)
NSY: 104227957 104228313
NTO: 104107635 104116841
NAU: 109223807 109226123
INI: 109148056 109193543
ITR: 116010427 116029088
SIND: 105157101 105170139
OEU: 111388353 111394843 111394844
EGT: 105957028 105959765
SSPL: 121755671 121758317 121761887 121765547
SMIL: 131020407 131022361
SHIS: 125208823 125222222
APAN: 127241071 127246011
HAN: 110873825 110879946 110930151 110941795
ECAD: 122589605 122609866
LSV: 111877732 111877733 111877734 111877756 111895388 111909735
CCAV: 112510132 112510388 112514549
DCR: 108195887 108220046
CSIN: 114315105
RVL: 131309926 131309927 131313121
AEW: 130754337 130761079 130761128
BVG: 104894042 104899916
SOE: 110798610 110799455
CQI: 110683513 110688219 110700603 110726445
ATRI: 130799128 130814219
MOF: 131146344 131148010
NNU: 104602940
MING: 122076893
TSS: 122654450
PSOM: 113280589 113303555 113317764 113333991
OSA: 4326207 4330711(CHLP)
OBR: 102704037 121055138
OGL: 127763342 127773849
BDI: 100821798 100836154
ATS: 109757451 109766926
TDC: 119267922 119275794 119317865 119325740
TAES: 123061037 123069628 123078110 123128382 123138239 780623
TUA: 125514635
LPER: 127306108 127342370
LRD: 124659248 124659493 124693120 124693176
SBI: 8075711 8085832
ZMA: 100283007 103649981
MFLO: 136451896 136451909 136458038 136467724 136467741 136478094
SITA: 101769245 101784760
SVS: 117837921 117857077
PVIR: 120641609 120657231 120672971 120706447
PHAI: 112892306 112902015
PDA: 103716420 103718980
EGU: 105032269 105058545
MUS: 103989643 103996389
ZOF: 121981453 122025374 122038090 122056583
DCT: 110107118 110107874
PEQ: 110032603
AOF: 109834138
MSIN: 131226795 131242072
NCOL: 116252913 116253458
ATR: 110007115
SMO: SELMODRAFT_150713 SELMODRAFT_271030
PPP: 112275265 112295439 112296001
CRE: CHLRE_01g050950v5
VCN: VOLCADRAFT_77841
MNG: MNEG_11486
CSL: COCSUDRAFT_31829
CVR: CHLNCDRAFT_29491
APRO: F751_0551
OLU: OSTLU_119498(ggh)
OTA: OT_ostta02g02510
BPG: Bathy14g02760
MIS: MICPUN_91628
MPP: MICPUCDRAFT_49640
CME: CYME_CMJ154C
GSL: Gasu_07190
CCP: CHC_T00009478001
PTI: PHATRDRAFT_50650
FCY: FRACYDRAFT_267781(GGR)
TPS: THAPSDRAFT_10234
AAF: AURANDRAFT_31415
EHX: EMIHUDRAFT_432259
GTT: GUITHDRAFT_91519
PAQM: E0F26_06715
ALV: Alvin_2646
ATEP: Atep_05700(bchP)
TVI: Thivi_2414
TMB: Thimo_0922
MPUR: MARPU_13980
TSY: THSYN_31555
TTP: E6P07_13125
THIP: N838_12615
CJAP: GWK36_13340
THIM: KFB96_13295
TBOG: LT988_09015
TLR: Thiosp_04088(bchP)
TFRI: Thiofri_01159(bchP)
TWG: Thiowin_00724(bchP)
HHA: Hhal_1602
HHK: HH1059_06380(bchP)
HHC: M911_08255
EBS: ECTOBSL9_2972
PDQ: CL55_00013270
PANI: DCO16_03310
PCOS: C2747_06795
PWU: A8O14_08475
POLY: PSHI2_19040(bchP)
POLN: PSHI8_19050(bchP)
RAC: RA876_06160
LIM: L103DPR2_01008(kmo)
LIH: L63ED372_00664
HYR: BSY239_1278
HCZ: G9Q37_21655
MPT: Mpe_A2779
METP: C1M51_03440
RGE: RGE_33390(bchP)
RBN: RBXJA2T_09597
RDP: RD2015_1020
ROI: N4261_01125
ATER: MW290_02645
METR: BSY238_2473
BEB: AEM42_07610
RPOD: E0E05_11930
AGC: BSY240_3640
RROS: D4A92_02775
ABAW: D5400_05075
PDES: FE840_002465
BRA: BRADO1632(bchP)
BBT: BBta_6424(bchP)
BRS: S23_19290(bchP)
AOL: S58_59050
BRO: BRAD285_5768(bchP)
BRQ: CIT40_23885
BGZ: XH91_02710
BBET: F8237_24730
BROS: QUH67_09890
BOY: LQG66_15905
RPA: TX73_007880
RPB: RPB_3990
RPC: RPC_1304
RPD: RPD_3745
RPE: RPE_1338
RPT: Rpal_1721
RPX: Rpdx1_3987
RHOL: RBJ75_13090
BOS: BSY19_4030
MEA: Mex_1p5279(bchP)
MDI: METDI5879(bchP)
MEX: Mext_4822
MCH: Mchl_5289
MPO: Mpop_5367
MZA: B2G69_06095
MRD: Mrad2831_1854
MET: M446_3712
MOR: MOC_2259(bchP)
META: Y590_24640
MAQU: Maq22A_c01650(fixC)
MPHY: MCBMB27_01476
MEE: DA075_04020
METD: C0214_26380
METX: A3862_21655
METS: DK389_01100
METI: DK427_18055
MMES: MMSR116_22220
MTEA: DK419_04980
MIND: mvi_09110(bchP)
MOG: MMB17_13825
MTAD: M6G65_04510
MSL: Msil_2063
BBAR: RHAL1_00139(bchP)
RVA: Rvan_1004
RLAC: QMO75_03335
BVR: BVIR_564
BLAG: BLTE_02000(bchP)
MROS: EHO51_17145
MESZ: LNB28_08020
CMET: K6K41_01510
AUZ: Sa4125_27490
AUB: LXB15_06250
JIE: OH818_05165
BSB: Bresu_3058
BRL: BZG35_15510
BREA: HZ989_04545
RUT: FIU92_10010
JAN: Jann_0167(bchP)
RDE: RD1_0146(bchP)
RLI: RLO149_p940650(bchP)
RPON: G3256_18955
RFU: ROLI_002420(kmo)
DSH: Dshi_3528(bchP)
RED: roselon_01089
SUAM: BOO69_19355
SUAL: KDD17_18420
TOM: BWR18_20045
RMM: ROSMUCSMR3_00875
ROK: RAK1035_3745
RID: RIdsm_01785
ROM: EI983_05580
ROH: FIU89_14070
THAA: CFI11_23675
ROT: FIV09_18125
RMH: LVO79_15100
MALU: KU6B_16760
PLCG: RVY76_14000
MARU: FIU81_13800
RMAI: MACH21_32910(bchP)
RSP: RSP_0277(bchP)
RSH: Rsph17029_1920
RSQ: Rsph17025_1018
RSK: RSKD131_1603
CAZT: LV780_04440
RCP: RCAP_rcc00673(bchP)
RBL: B6K69_03440
FYT: QF092_06670
PTP: RCA23_c29730(bchP)
RSU: NHU_00205
RHM: B5V46_02425
RHC: RGUI_1992
LVS: LOKVESSMR4R_03330
GEH: HYN69_05455
TAW: EI545_18875
POZ: I0K15_16865
NSM: JO391_16395
PBAE: P8S53_17155
RBG: BG454_02965
FAQ: G5B39_09965
RBX: I3V23_09445
HBC: AEM38_14345
NOT: C7W88_00530
NGF: FRF71_09195
NOG: GKE62_08485
NCP: U0041_19895
SPHI: TS85_23035
SSAN: NX02_18305
SCHY: GVO57_11495
SAER: NEF64_07815
SGLC: M1K48_13670
SQO: NMP03_02265
SRAD: LLW23_12285
CIJ: WG74_05085
SLAA: EUU25_10315
BLAS: BSY18_2715
BFW: B5J99_04525
PALG: HFP57_06900
PARJ: J4G78_07490
SAND: H3309_05840
POQ: KZX46_18575
PMEA: KTC28_16885
ALH: G6N82_11480
ARUE: QQX03_04260
ELQ: Ga0102493_111829
ERK: CD351_13920
ERF: FIU90_13875
PNS: A9D12_01330
ERYT: KDC96_00965
PORL: BG023_112679
PHZ: CHX26_14545
POT: E2E27_07290
PORC: CBR61_14970
AMV: ACMV_18910(bchP)
RFL: Rmf_21930(bchP)
SRF: LHU95_14010
RAP: RHOA_2392(bchP)
NCB: C0V82_18025
SKT: IGS68_17205
SMUC: JL100_008830
SROE: JL101_015385
RRU: Rru_A0629
RRF: F11_03225
RCE: RC1_2080(bchP)
RPM: RSPPHO_00051(bchP)
ELIO: KO353_02765
THAR: T8K17_11905
SULR: B649_08370
ANT: Arnit_0931
SUN: SUN_1446
NAM: NAMH_1575
NAP: C3L23_08185
CMED: FE773_02195
CPAF: C6V80_00880
SYN: sll1091
SYZ: MYO_117820
SYY: SYNGTS_1764(chlP)
SYT: SYNGTI_1764(chlP)
SYS: SYNPCCN_1763(chlP)
SYQ: SYNPCCP_1763(chlP)
SYJ: D082_12250(chlP)
SYO: C7I86_09185(chlP)
SYNH: HTZ78_11470(chlP)
SYC: syc1129_d(chlP)
SYU: M744_01055
SYF: Synpcc7942_0385
SYD: Syncc9605_1240
SYE: Syncc9902_1239
SYG: sync_1282(chlP)
SYR: SynRCC307_1267(chlP)
SYX: SynWH7803_1317(chlP)
CYA: CYA_0072(chlP)
CYB: CYB_1761(chlP)
SYNE: Syn6312_1774
SYNP: Syn7502_00552
SYNK: KR100_09500
SYNR: KR49_02790
SYND: KR52_10480
SYH: Syncc8109_1450(chlP)
SYNW: SynWH8103_01240(chlP)
SYNC: CB0101_03220(chlP)
SYNY: BM449_10985
SYNZ: H8F24_15665(chlP)
DSL: Dacsa_0177
SYW: SYNW1097(chlP)
CGC: Cyagr_0506
CYI: CBM981_0621(chlP)
PMA: Pro_0832(chlP)
PMM: PMM0760(chlP)
PMT: PMT_0577
PMN: PMN2A_0164
PMI: PMT9312_0768
PMB: A9601_08221(chlP)
PMC: P9515_08231(chlP)
PMF: P9303_16731(chlP)
PMG: P9301_08201(chlP)
PMH: P9215_08541(chlP)
PMJ: P9211_10031(chlP)
PME: NATL1_07961(chlP)
PRC: EW14_0849
PRM: EW15_0845
WNA: KA717_28720(chlP)
CMP: Cha6605_5468
CYN: Cyan7425_1664
CEP: Cri9333_1154
TVN: NIES2134_123820(chlP)
SLW: BRW62_10580
TEL: tll0150(chlP)
THN: NK55_09970(chlP)
THEC: FFX45_11910(chlP)
THEY: JW907_01475(chlP)
TSQ: D3A95_11385(chlP)
AMR: AM1_2046(chlP)
TSZ: OOK60_18035(chlP)
LEN: LEP3755_60180
LET: O77CONTIG1_04651
LBO: LBWT_24580
LEPV: J4558_02365
KOV: K9N68_30930(chlP)
LSC: KIK02_02930(chlP)
LSK: J5X98_01545(chlP)
HHG: XM38_015980(chlP_2)
PSEU: Pse7367_0953
PSER: ABRG53_0355(chlP)
PGX: OA858_16810(chlP)
THEU: HPC62_18410(chlP)
TOG: HNI00_14050(chlP)
TSIN: OXH18_08110(chlP)
GLP: Glo7428_1539
CHON: NIES4102_17970(chlP)
GDU: P0S91_17690(chlP)
GEN: GM3709_1900
GEE: GM3708_1376
CAN: Cyan10605_1785
CSN: Cyast_1975
CYL: AA637_11455(chlP)
SYP: SYNPCC7002_A2476(chlP)
SYV: AWQ23_12350
SYL: AWQ21_12135
LEP: Lepto7376_1028
SYNN: NIES970_05430(chlP)
PIP: FEK30_01995(chlP)
MAR: MAE_50020(chlP)
MPK: VL20_2943
MIQ: B5D77_11380
MVZ: myaer102_23260(chlP)
HAO: PCC7418_3094
ENN: FRE64_09415(chlP)
CYU: UCYN_09570
CYT: cce_3146(chlP)
CWA: CwatDRAFT_1268
CYP: PCC8801_0178
CYH: Cyan8802_0173
CYC: PCC7424_4276
CYJ: Cyan7822_2454
TER: Tery_1823
ARP: NIES39_E00570(chlP)
PAGH: NIES204_40830(chlP)
PPSU: NO713_00939(chlP)
PRUN: PCC7821_04834(chlP)
MVAG: D0A34_25150(chlP)
LFS: HFV01_21020(chlP)
LIX: H2674_05930(chlP)
OXY: HCG48_23715(chlP)
OAC: Oscil6304_0501
ONI: Osc7112_5726
MPRO: BJP34_22960
PHOR: JWS08_16450(chlP)
PYH: NEA10_16600(chlP)
MIC: Mic7113_4883
GEI: GEI7407_0045
GVI: glr4377(chlP)
GLJ: GKIL_3454(chlP)
GML: ISF26_05925(chlP)
ANA: alr0128(chlP)
NPU: Npun_F3720
NOS: Nos7107_1348
NOP: Nos7524_5371
NON: NOS3756_20520
NFL: COO91_03837
NOE: CLI64_23700(chlP)
NSH: GXM_02661
NED: HUN01_21950(chlP)
NPZ: ACX27_16515
NLK: NIES25_38100
NCW: NIES2107_69540
NCF: ANSO36C_57040(chlP)
AVA: Ava_1497
NAZ: Aazo_4038
ANB: ANA_C12069(chlP)
ACY: Anacy_4688
AWA: AA650_02215
ANN: EH233_05305(chlP)
CSG: Cylst_2521
RSIN: B6N60_01483
HBQ: QI031_26515(chlP)
CALO: Cal7507_0409
CALT: Cal6303_4336
CALH: IJ00_23305
CALN: NIES2098_01640
CALS: NIES3974_17590
RIV: Riv7116_2307
MDP: NIES3275_45960
FIS: FIS3754_07060
NSPH: BDGGKGIB_01472(kmo_1)
DOU: BMF77_03658(kmo)
DFS: HGD76_23605(chlP)
DHT: NG743_16125(chlP)
DCM: NIES806_37050
DOT: EZY12_24650(chlP)
DOZ: HEP80_19655(chlP)
DOC: HEQ26_02025(chlP)
CCUR: IAR63_08040(chlP)
CRK: L3I90_00445(chlP)
AFLO: HEQ12_15450(chlP)
STOQ: K2F26_14950(chlP)
SKV: NIES73_01580
AEE: IM676_10450(chlP)
RCS: NIES932_03680
OCF: WJM97_12040(chlP)
TOQ: HCG51_14735(chlP)
TTQ: NIES37_63310
ALAX: NIES50_23260
SCYT: SAMD_68550
SCYS: NIES4073_40300
BSEN: DP114_18890(chlP)
BOX: DP113_18820(chlP)
NCN: BZZ01_13220
CTHE: Chro_3960
PLP: Ple7327_3206
SCS: Sta7437_1400
STAN: STA3757_13410(chlP)
GLT: GlitD10_2510(bchP)
GCY: LQF76_09125(chlP)
RRS: RoseRS_3265
RCA: Rcas_3751
CAU: Caur_2087
CHL: Chy400_2250
CAG: Cagg_2633
CALL: OZ401_000757
VAB: WPS_12930 WPS_26110
CTM: Cabther_A0150
CVL: J8C06_00995
CHLO: J8C02_00760
GPH: GEMMAAP_06365
GGR: HKW67_08925
PSPC: Strain318_000118
CTE: CT2256(bchP)
CPC: Cpar_0021
CLZ: BIU88_11310
CCH: Cag_0035
CPH: Cpha266_0044
CPB: Cphamn1_0023
CLI: Clim_0022
PVI: Cvib_0020
PLT: Plut_0016
PPH: Ppha_0029
PAA: Paes_0023
PROC: Ptc2401_00022(cbrA)
PRS: B9H02_00110
PROS: CHL67_00125
PROW: OO006_00120
PROI: OO005_00115
CTS: Ctha_1271
TYE: THEYE_A1608
DTP: JZK55_04270
 » show all
Reference
1  [PMID:7947681]
  Authors
Bollivar DW, Wang S, Allen JP, Bauer CE
  Title
Molecular genetic analysis of terminal steps in bacteriochlorophyll a biosynthesis: characterization of a Rhodobacter capsulatus strain that synthesizes geranylgeraniol-esterified bacteriochlorophyll a.
  Journal
Biochemistry 33:12763-8 (1994)
DOI:10.1021/bi00209a006
  Sequence
[rcp:RCAP_rcc00673]
Reference
2  [PMID:10572128]
  Authors
Addlesee HA, Hunter CN
  Title
Physical mapping and functional assignment of the geranylgeranyl-bacteriochlorophyll reductase gene, bchP, of Rhodobacter sphaeroides.
  Journal
J Bacteriol 181:7248-55 (1999)
DOI:10.1128/JB.181.23.7248-7255.1999
  Sequence
[rcp:RCAP_rcc00673]
Reference
3  [PMID:11872709]
  Authors
Addlesee HA, Hunter CN
  Title
Rhodospirillum rubrum possesses a variant of the bchP gene, encoding geranylgeranyl-bacteriopheophytin reductase.
  Journal
J Bacteriol 184:1578-86 (2002)
DOI:10.1128/JB.184.6.1578-1586.2002
  Sequence
[rru:Rru_A0629]
Reference
4  [PMID:18846281]
  Authors
Harada J, Miyago S, Mizoguchi T, Azai C, Inoue K, Tamiaki H, Oh-oka H
  Title
Accumulation of chlorophyllous pigments esterified with the geranylgeranyl group  and photosynthetic competence in the CT2256-deleted mutant of the green sulfur bacterium Chlorobium tepidum.
  Journal
Photochem Photobiol Sci 7:1179-87 (2008)
DOI:10.1039/b802435a
Other DBs
ExplorEnz - The Enzyme Database: 1.3.1.111
IUBMB Enzyme Nomenclature: 1.3.1.111
ExPASy - ENZYME nomenclature database: 1.3.1.111
BRENDA, the Enzyme Database: 1.3.1.111
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