KEGG   ENZYME: 1.4.2.1
Entry
EC 1.4.2.1                  Enzyme                                 
Name
glycine dehydrogenase (cytochrome);
glycine---cytochrome c reductase
Class
Oxidoreductases;
Acting on the CH-NH2 group of donors;
With a cytochrome as acceptor
Sysname
glycine:ferricytochrome-c oxidoreductase (deaminating)
Reaction(IUBMB)
glycine + H2O + 2 ferricytochrome c = glyoxylate + NH3 + 2 ferrocytochrome c + 2 H+ [RN:R00364]
Reaction(KEGG)
R00364
Substrate
glycine [CPD:C00037];
H2O [CPD:C00001];
ferricytochrome c [CPD:C00125]
Product
glyoxylate [CPD:C00048];
NH3 [CPD:C00014];
ferrocytochrome c [CPD:C00126];
H+ [CPD:C00080]
History
EC 1.4.2.1 created 1976
Pathway
ec00260  Glycine, serine and threonine metabolism
ec01100  Metabolic pathways
Reference
1  [PMID:5016640]
  Authors
Sanders HK, Becker GE, Nason A.
  Title
Glycine-cytochrome c reductase from Nitrobacter agilis.
  Journal
J Biol Chem 247:2015-25 (1972)
Other DBs
ExplorEnz - The Enzyme Database: 1.4.2.1
IUBMB Enzyme Nomenclature: 1.4.2.1
ExPASy - ENZYME nomenclature database: 1.4.2.1
BRENDA, the Enzyme Database: 1.4.2.1
CAS: 9075-55-2
LinkDB

KEGG   REACTION: R00364
Entry
R00364                      Reaction                               
Name
glycine:ferricytochrome-c oxidoreductase (deaminating)
Definition
Glycine + H2O + 2 Ferricytochrome c <=> Glyoxylate + Ammonia + 2 Ferrocytochrome c + 2 H+
Equation
C00037 + C00001 + 2 C00125 <=> C00048 + C00014 + 2 C00126 + 2 C00080
Reaction class
RC00016  C00125_C00126
RC00018  C00037_C00048
RC02834  C00014_C00037
Enzyme
1.4.2.1
Pathway
rn00260  Glycine, serine and threonine metabolism
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.4  Acting on the CH-NH2 group of donors
   1.4.2  With a cytochrome as acceptor
    1.4.2.1
     R00364  Glycine + H2O + 2 Ferricytochrome c <=> Glyoxylate + Ammonia + 2 Ferrocytochrome c + 2 H+
Other DBs
RHEA: 16912
LinkDB

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