KEGG   ENZYME: 1.5.1.23
Entry
EC 1.5.1.23                 Enzyme                                 
Name
tauropine dehydrogenase;
2-N-(D-1-carboxyethyl)taurine:NAD+ oxidoreductase (taurine-forming)
Class
Oxidoreductases;
Acting on the CH-NH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
N2-(D-1-carboxyethyl)taurine:NAD+ oxidoreductase (taurine-forming)
Reaction(IUBMB)
tauropine + NAD+ + H2O = taurine + pyruvate + NADH + H+ [RN:R01683]
Reaction(KEGG)
R01683
Substrate
tauropine [CPD:C01616];
NAD+ [CPD:C00003];
H2O [CPD:C00001]
Product
taurine [CPD:C00245];
pyruvate [CPD:C00022];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
In the reverse reaction, alanine can act instead of taurine, but more slowly, and 2-oxobutanoate and 2-oxopentanoate can act instead of pyruvate.
History
EC 1.5.1.23 created 1989
Orthology
K23235  tauropine dehydrogenase
Genes
GAE121376157
HRF124130928 124141241
HRJ124275228
MMER123523678 123557744
LAK106154406 106176697
NVE5519798
EPA110245428 110253015
ATEN116289858 116289859 116298751 116298753 116298754 116298769
PDAM113683789
SPIS111324053 111324069
Reference
1  [PMID:3769931]
  Authors
Gade G.
  Title
Purification and properties of tauropine dehydrogenase from the shell adductor muscle of the ormer, Haliotis lamellosa.
  Journal
Eur J Biochem 160:311-8 (1986)
DOI:10.1111/j.1432-1033.1986.tb09973.x
Other DBs
ExplorEnz - The Enzyme Database: 1.5.1.23
IUBMB Enzyme Nomenclature: 1.5.1.23
ExPASy - ENZYME nomenclature database: 1.5.1.23
BRENDA, the Enzyme Database: 1.5.1.23
CAS: 104645-74-1
LinkDB

DBGET integrated database retrieval system