| Entry |
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| Name |
monodehydroascorbate reductase (NADH);
NADH:semidehydroascorbic acid oxidoreductase;
MDHA;
semidehydroascorbate reductase;
AFR (ambiguous);
AFR-reductase;
ascorbic free radical reductase;
ascorbate free radical reductase;
SOR (ambiguous);
MDAsA reductase (NADPH);
SDA reductase;
NADH:ascorbate radical oxidoreductase;
NADH-semidehydroascorbate oxidoreductase;
ascorbate free-radical reductase;
NADH:AFR oxidoreductase;
monodehydroascorbate reductase (NADH2)
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| Class |
Oxidoreductases;
Acting on NADH or NADPH;
With a quinone or similar compound as acceptor
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| Sysname |
NADH:monodehydroascorbate oxidoreductase
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| Reaction(IUBMB) |
NADH + H+ + 2 monodehydroascorbate = NAD+ + 2 ascorbate [RN: R00095]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| History |
EC 1.6.5.4 created 1961
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| Pathway |
| ec00053 | Ascorbate and aldarate metabolism |
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| Orthology |
| K08232 | monodehydroascorbate reductase (NADH) |
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| Genes |
| AJM: | 119036550 119047621 119051995 |
| ATH: | AT1G63940(MDAR6) AT3G09940(MDHAR) AT3G27820(MDAR4) AT3G52880(MDAR1) AT5G03630(ATMDAR2) |
| ALY: | 9307119 9311471 9313959 9318712 9323993 |
| CRB: | 17881985 17885113 17887316 17893776 17894235 |
| CSAT: | 104704015 104708760 104710624 104711845 104714747 104734386 104737819 104748097 104753060 104757987 104764692 104768545 104780024 104781139 104790435 104791545 |
| EUS: | EUTSA_v10004089mg EUTSA_v10010391mg EUTSA_v10013480mg EUTSA_v10023425mg |
| BRP: | 103838242 103841218 103854214 103855533 103859275 103875190 |
| BNA: | 106349230 106367807 106367930 106382143 106385675 106390242 106424661 106428595 106443981 106450519 106452428 111204212 125589758 |
| BOE: | 106301085 106306705 106312328 106312828 106325201 106333228 106335271 |
| RSZ: | 108810462 108825474 108847599 108855688 108863493 130495016 130499724 130505704 |
| THJ: | 104809369 104816363 104823486 104823945 |
| CPAP: | 110807062 110807690 110822793 |
| CIT: | 102611741 102612075 102615220 |
| CIC: | CICLE_v10011764mg CICLE_v10015090mg CICLE_v10019842mg |
| PVY: | 116107428 116107508 116119683 116122994 116123711 116131868 116131869 116134133 116136395 116136397 116136398 116136399 116136400 |
| MINC: | 123196790 123206053 123211808 123221933 123224175 |
| TCC: | 18593828 18598191 18600776 18606587 |
| GRA: | 105765259 105776449 105782180 105786356 105798324 105799692 |
| GHI: | 107888685 107889553 107892280 107895291 107895776 107908705 107915319 107919983 107925660 107928204 107947063 107949020 |
| GAB: | 108457017 108464012 108467230 108488427 108489653 108489855 |
| HSYR: | 120114401 120122443 120136482 120159485 120181812 120185565 120192875 120193724 120200844 |
| DZI: | 111278352 111287618 111289860 111292883 111294906 111296493 111311743 |
| EGR: | 104416090 104422613 104443846 |
| GMX: | 100301881 100500084 100787700 100816879 100819919 |
| GSJ: | 114372005 114382216 114390772 114400220 114421044 |
| PVU: | PHAVU_002G292800g PHAVU_007G230300g PHAVU_008G155600g |
| VRA: | 106759244 106769137 106772343 |
| VAR: | 108326480 108329681 108347624 |
| VUN: | 114179951 114185184 114191905 |
| VUM: | 124822353 124827297 124848978 |
| CCAJ: | 109791924 109806440 109818059 |
| APRC: | 113853900 113861690 113873469 |
| MTR: | 25483862 25498021 25502104 |
| TPRA: | 123889303 123904040 123906961 123915891 |
| CAM: | 101489296 101503692 101515028 |
| PSAT: | 127092723 127100829 127128010 |
| VVO: | 131603667 131603670 131609108 131637352 131644683 131644690 |
| LJA: | 130711994 130717875 130729549 |
| ADU: | 107476212 107479871 107485974 107493930 107495052 |
| AIP: | 107605336 107626404 107633439 107635140 107648266 |
| AHF: | 112696669 112697310 112728860 112732608 112744255 112754484 112755216 112758770 112790853 112797562 |
| LANG: | 109334795 109336207 109337387 109347278 109348332 109354873 |
| PCIN: | 129302660 129322020 |
| QSA: | O6P43_004635 O6P43_005911 O6P43_008951 O6P43_009540 O6P43_024143 |
| FVE: | 101291334 101298048 101300833 |
| RCN: | 112166452 112179200 112188943 112193014 |
| PPER: | 18769754 18777529 18778537 18783812 |
| PMUM: | 103326343 103329845 103337588 103339713 |
| PAVI: | 110753567 110762513 110763722 110772950 |
| PDUL: | 117622221 117624575 117628822 117634064 |
| MDM: | 103404333 103411764 103430138 103433944 103453944 114820098 |
| MSYL: | 126588664 126593871 126599571 126600483 126610556 126614749 |
| PXB: | 103926938 103927400 103934424 103956392 103963642 103963964 103965840 |
| ZJU: | 107415283 107429997 107430170 107434770 107434950 125421739 132799157 132800370 |
| MNT: | 21393482 21396944 21403414 21406966 |
| CSAV: | 115699645 115709328 115716638 115724575 |
| CSV: | 101203883 101206557 101207933 101210277 101214011 |
| CMO: | 103482782 103486590 103493361 103498081 103500882 |
| BHJ: | 120068324 120074691 120080109 120089726 120091032 |
| MCHA: | 111006548 111012803 111013604 111014281 111023941 |
| CMAX: | 111469045 111471214 111478497 111481646 111483271 111486955 111489099 |
| CMOS: | 111430072 111435740 111435980 111441711 111445613 111447513 111463193 |
| CPEP: | 111779821 111781660 111790217 111798545 111809016 111809047 111810487 |
| RCU: | 8258892 8281778 8287431 |
| MEAN: | 126673909 126677306 126678446 |
| HBR: | 110635548 110636587 110641312 110646618 110652056 110669250 |
| MESC: | 110602725 110621121 110622740 110629838 |
| POP: | 18100056 7479290 7496837 |
| PEU: | 105111476 105121800 105129106 |
| PALZ: | 118033742 118048220 118052740 |
| PNZ: | 133668126 133678076 133689573 |
| JRE: | 108992868 108997427 109005337 109005339 |
| CILL: | 122276624 122279925 122290257 122302584 |
| CAVE: | 132176107 132183099 132192287 |
| QSU: | 111997187 111997481 112035922 |
| QLO: | 115953401 115953487 115971897 115976639 |
| TWL: | 119995697 119999236 120013509 |
| VVI: | 100233035 100253570 100267896 |
| VRI: | 117904568 117920351 117931154 |
| SLY: | 101253550 101264360(AFRR) 778288(MDHAR) |
| SPEN: | 107011268 107028810 107031233 |
| SOT: | 102583368 102586212 102595145 |
| SSTN: | 125841835 125847555 125870593 |
| SDUL: | 129872339 129882116 129890096 |
| CANN: | 107843212 107860653 107864529 |
| LBB: | 132621318 132629871 132629878 132629879 132634007 132634855 |
| NTA: | 107768281 107775678 107779915 107818762 107820316 107828222 |
| NSY: | 104218023 104223412 104243374 |
| NTO: | 104100849 104109753 104113490 |
| NAU: | 109216755 109229738 109232426 |
| INI: | 109155227 109158326 109165763 109178257 109182072 109182073 |
| ITR: | 115998870 115999725 116006714 116006715 116020037 116032709 |
| SIND: | 105158249 105161774 105174100 105177119 |
| OEU: | 111370734 111376986 111390365 111404068 111407593 111409325 111412842 |
| EGT: | 105960488 105960994 105969400 105973777 |
| SSPL: | 121748521 121762614 121769430 121771818 121780374 121782312 121786129 121795507 121799065 |
| SMIL: | 130996567 131008693 131024925 |
| SHIS: | 125208390 125211769 125212907 125215519 |
| APAN: | 127243400 127250391 127251078 127251866 |
| HAN: | 110868650 110895508 110904060 110911227 110930440 |
| ECAD: | 122580018 122583687 122599265 122599636 122605139 |
| LSV: | 111876422 111897439 111901112 111905025 111907781 |
| CCAV: | 112513060 112519052 112519708 112521928 112529264 |
| DCR: | 108210101 108213446 108215538 108219553 108228047 |
| CSIN: | 114279341 114280285 114284032 114323822 |
| RVL: | 131304829 131320851 131333443 |
| AEW: | 130757496 130765878 130768323 130776944 130788907 130795300 |
| BVG: | 104892246 104898398 104906670 |
| SOE: | 110778274 110782792 110805587 |
| CQI: | 110695775 110719579 110722597 110729344 110737923 |
| ATRI: | 130801265 130812768 130818193 |
| MOF: | 131157142 131162004 131168479 |
| NNU: | 104586919 104587231 104588006 104600202 |
| MING: | 122058397 122076849 122079036 122079729 122082078 |
| TSS: | 122652483 122655445 122655848 122658918 122663665 122671754 |
| PSOM: | 113299232 113300090 113310213 113319008 113321954 113358378 |
| OSA: | 4330468(49D11.20b) 4330469(49D11.20a) 4344670(MDAR5) 4346299 4347885 |
| OBR: | 102704954 102710804 102716626 102719416 |
| OGL: | 127763737 127781823 127784410 |
| BDI: | 100823694 100824394 100824698 100825974 100836159 |
| ATS: | 109754069 109761648 109774107 109781875 109781876 |
| TDC: | 119287164 119294520 119317587 119317589 119326798 119326800 119329526 119334670 119335448 119338888 |
| TAES: | 101290625 123087382 123090542 123095594 123128134 123128135 123137934 123145229 123145231 123147394 123152701 123158891 123162424 123165032 123170534 |
| TUA: | 125524693 125524802 125550176 |
| LPER: | 127303050 127306490 127306491 127314797 127316089 |
| LRD: | 124657631 124657907 124685328 124686728 124692960 124692961 |
| SBI: | 110432213 110436954 8057994 8073853 |
| ZMA: | 100193942 100272772 100279805 100382120 100501585 |
| MFLO: | 136467566 136467591 136467592 136477026 136477059 136500610 136549666 |
| SITA: | 101756689 101758567 101773570 101785289 |
| SVS: | 117835013 117843915 117859493 117861672 |
| PVIR: | 120649632 120656965 120656966 120659993 120671225 120677744 120678334 120711394 120713832 |
| PHAI: | 112880086 112897293 112897809 112899809 112899942 112900025 |
| PDA: | 103701999 103711527 103715398 103715799 |
| EGU: | 105056270 105058742 105059480 105061389 |
| MUS: | 103976516 103983599 103985262 103987358 |
| ZOF: | 121980300 121980702 121984213 121987511 121992519 121992939 121996459 121996934 122009392 122016496 122043080 122047580 |
| DCT: | 110092726 110092922 110103032 110116718 |
| PEQ: | 110018467 110019304 110025406 110033183 |
| AOF: | 109819654 109828964 109830430 109836737 109844950 |
| MSIN: | 131232485 131235712 131237829 |
| NCOL: | 116248101 116259347 116262308 116264701 |
| ATR: | 18424141 18430531 18441365 18447855 |
| SMO: | SELMODRAFT_100177 SELMODRAFT_131995 SELMODRAFT_145962 SELMODRAFT_170362 SELMODRAFT_272297 SELMODRAFT_440551 |
| PPP: | 112278733 112287000 112291911 112292445 |
| CSL: | COCSUDRAFT_22455 COCSUDRAFT_33977 |
| GSL: | Gasu_04600 Gasu_31000 |
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| Reference |
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| Authors |
Schulze HU, Schott HH, Staudinger H. |
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| Title |
[The isolation and characterization of a NADH: semidehydroascorbic acid oxidoreductase from Neurospora crassa] |
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| Journal |
Hoppe Seylers Z Physiol Chem 353:1931-42 (1972) |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 1.6.5.4 |
| ExPASy - ENZYME nomenclature database: | 1.6.5.4 |
| BRENDA, the Enzyme Database: | 1.6.5.4 |
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| LinkDB |
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