KEGG   ENZYME: 1.7.1.2
Entry
EC 1.7.1.2                  Enzyme                                 

Name
nitrate reductase [NAD(P)H];
assimilatory nitrate reductase ( ambiguous);
assimilatory NAD(P)H-nitrate reductase;
NAD(P)H bispecific nitrate reductase;
nitrate reductase (reduced nicotinamide adenine dinucleotide (phosphate));
nitrate reductase NAD(P)H;
NAD(P)H-nitrate reductase;
nitrate reductase [NAD(P)H2];
NAD(P)H2:nitrate oxidoreductase
Class
Oxidoreductases;
Acting on other nitrogenous compounds as donors;
With NAD+ or NADP+ as acceptor
Sysname
nitrite:NAD(P)+ oxidoreductase
Reaction(IUBMB)
nitrite + NAD(P)+ + H2O = nitrate + NAD(P)H + H+ [RN:R00794 R00796]
Reaction(KEGG)
R00794 R00796
Substrate
nitrite [CPD:C00088];
NAD+ [CPD:C00003];
NADP+ [CPD:C00006];
H2O [CPD:C00001]
Product
nitrate [CPD:C00244];
NADH [CPD:C00004];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
An iron-sulfur molybdenum flavoprotein.
History
EC 1.7.1.2 created 1961 as EC 1.6.6.2, transferred 2002 to EC 1.7.1.2
Pathway
ec00910  Nitrogen metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K10534  nitrate reductase (NAD(P)H)
Genes
ATH: AT1G37130(NIA2) AT1G77760(NIA1)
ALY: 9325221 9329985
CRB: 17895831 17897387
CSAT: 104702559 104713453 104742100 104743831 104751674 104757885 104777515
EUS: EUTSA_v10003628mg EUTSA_v10018092mg
BRP: 103830551 103832206 103853097
BNA: 106353470 106354597 106368948 106397776 106400358 106411852 111210558
BOE: 106300064 106300202 106327343
RSZ: 108814131 108817773 108827738 108832026
THJ: 104813138 104813644 104817024
CPAP: 110815200
CIT: 102610866
PVY: 116131487
TCC: 18592259
EGR: 104450466
LJA: Lj0g3v0006719.1(Lj0g3v0006719.1)
ADU: 107460801
AIP: 107606095
FVE: 101295234
RCN: 112176179
PPER: 18790070
PMUM: 103332932
PAVI: 110753196
PDUL: 117637123
MNT: 21403045
CSV: 101216001(NR1) 101219000(NR2) 101219242(NR3)
RCU: 8274143
JCU: 105638879
HBR: 110647032
MESC: 110608013
PALZ: 118041743
QLO: 115959748
TWL: 120009223
VVI: 100264320
SLY: 100736473(NR)
SPEN: 107004448
SOT: 102577728(NR3)
CANN: 107867964
NTA: 107785409(NIA2) 107820848 107823732(NIA1)
NTO: 104097998
NAU: 109206453
INI: 109176053
ITR: 116001570
EGT: 105974302
ECAD: 122588863
CCAV: 112504364
CSIN: 114286364
BVG: 104887841
SOE: 110786500
NCOL: 116262783
DOSA: Os02t0770800-01(Os02g0770800) Os08t0468100-01(Os08g0468100) Os08t0468700-00(Os08g0468700)
EGU: 105035363
DCT: 110097032
PEQ: 110019783
ATR: 18423189
VCN: VOLCADRAFT_76569(nitA)
MNG: MNEG_1964
MIS: MICPUN_113975(nia)
NCR: NCU05298(nit-3)
NTE: NEUTE1DRAFT80350(NEUTE1DRAFT_80350)
MGR: MGG_06062
MAW: MAC_08624
BFU: BCIN_07g01270(BcniaD)
MBE: MBM_01744
ANG: ANI_1_2088064(An07g08910) ANI_1_2090064(An07g08920) ANI_1_802074(An08g05610)
PBL: PAAG_03766 PAAG_12411(PAAG_07727)
PTE: PTT_08192
SMIN: v1.2.036677.t1(symbB.v1.2.036677.t1) v1.2.039611.t1(symbB.v1.2.039611.t1)
 » show all
Reference
1
  Authors
Nason, A.
  Title
Nitrate reductases.
  Journal
In: Boyer, P.D., Lardy, H. and Myrback, K. (Eds.), The Enzymes, 2nd ed., vol. 7, Academic Press, New York, 1963, p. 587-607.
Reference
2  [PMID:5864033]
  Authors
Paneque A, Del Campo FF, Ramirez JM, Losada M.
  Title
Flavin nucleotide nitrate reductase from spinach.
  Journal
Biochim Biophys Acta 109:79-85 (1965)
DOI:10.1016/0926-6585(65)90092-0
Reference
3  [PMID:11289301]
  Authors
Campbell WH.
  Title
Structure and function of eukaryotic NAD(P)H:nitrate reductase.
  Journal
Cell Mol Life Sci 58:194-204 (2001)
DOI:10.1007/PL00000847
Reference
4  [PMID:8534676]
  Authors
Berks BC, Ferguson SJ, Moir JW, Richardson DJ
  Title
Enzymes and associated electron transport systems that catalyse the respiratory reduction of nitrogen oxides and oxyanions.
  Journal
Biochim Biophys Acta 1232:97-173 (1995)
DOI:10.1016/0005-2728(95)00092-5
Other DBs
ExplorEnz - The Enzyme Database: 1.7.1.2
IUBMB Enzyme Nomenclature: 1.7.1.2
ExPASy - ENZYME nomenclature database: 1.7.1.2
BRENDA, the Enzyme Database: 1.7.1.2
CAS: 9029-27-0
LinkDB

DBGET integrated database retrieval system