Entry
Name
selenate reductase (cytochrome c);
serA (gene name);
serB (gene name);
serC (gene name);
selenite:reduced acceptor oxidoreductase;
selenate reductase
Class
Oxidoreductases;
Other oxidoreductases;
Sole sub-subclass for oxidoreductases that do not belong in the other subclasses
BRITE hierarchy
Sysname
ferricytochrome c:selenite oxidoreductase
Reaction(IUBMB)
2 ferricytochrome c + selenite + H2O = 2 ferrocytochrome c + selenate [RN:
R07229 ]
Reaction(KEGG)
Substrate
Product
Comment
The periplasmic enzyme from the bacterium Thauera selenatis is a complex comprising three heterologous subunits (alpha, beta and gamma) that contains a guanylyl molybdenum cofactor, as well as multiple iron-sulfur clusters and heme b. The enzyme reduces selenate to selenite using electrons provided by a diheme cytochrome c4, which receives the electrons from the membrane quinone pool via EC
7.1.1.8 , quinol---cytochrome-c reductase. Nitrate, nitrite, chlorate and sulfate are not substrates.
History
EC 1.97.1.9 created 2003, modified 2024
Pathway
Orthology
K07309 Tat-targeted selenate reductase subunit YnfE
K07310 Tat-targeted selenate reductase subunit YnfF
K12527 putative selenate reductase
K17050 selenate/chlorate reductase subunit alpha
K17051 selenate/chlorate reductase subunit beta
K17052 selenate/chlorate reductase subunit gamma
Genes
ECO : b1587(ynfE) b1588(ynfF) b2878(ygfK)
ECJ : JW1579(ynfE) JW5260(ynfF) JW5923(ygfK)
ECD : ECDH10B_1720(ynfE) ECDH10B_1721(ynfF) ECDH10B_3053(ygfK)
EBW : BWG_1401(ynfE) BWG_1402(ynfF) BWG_2604(ygfK)
ECOK : ECMDS42_1257(ynfE) ECMDS42_1258(ynfF) ECMDS42_2378(ygfK)
ECOC : C3026_09145 C3026_09150 C3026_15785
ECS : ECs_2293(ynfF_2) ECs_2294(ynfF_3) ECs_3751(ygfK)
ECF : ECH74115_2296(ynfE) ECH74115_2297 ECH74115_4168
ETW : ECSP_2151(ynfE) ECSP_2152(ynfF) ECSP_3848(ygfK)
ELX : CDCO157_2130 CDCO157_2131 CDCO157_3504
EOI : ECO111_2056(ynfF) ECO111_3616(ygfK)
EOJ : ECO26_2291(ynfF) ECO26_3967(ygfK)
EOH : ECO103_1726(ynfE) ECO103_1727(ynfF) ECO103_3453(ygfK)
ECOO : ECRM13514_2075 ECRM13514_3733(ygfK)
ECOH : ECRM13516_1980 ECRM13516_1981 ECRM13516_3597(ygfK)
ESL : O3K_05075 O3K_12680 O3K_12685
ESO : O3O_12950 O3O_12955 O3O_20570
ESM : O3M_05120 O3M_12640 O3M_12645
ECK : EC55989_1752(ynfE) EC55989_1753(ynfF) EC55989_3165(ygfK)
ECG : E2348C_1671(ynfE) E2348C_1672(ynfF)
EOK : G2583_1981(ynfE) G2583_1982(ynfF) G2583_3532(ygfK)
ELR : ECO55CA74_09725 ECO55CA74_09730 ECO55CA74_16835
ELH : ETEC_1621 ETEC_1622 ETEC_3072
ECW : EcE24377A_1794(ynfE) EcE24377A_1795 EcE24377A_3204
EUN : UMNK88_2047 UMNK88_3570
ENA : ECNA114_1632(ynfE) ECNA114_2919(ygfK)
ECOS : EC958_1805(ynfE) EC958_3159(ygfK)
ECV : APECO1_3648(ygfK) APECO1_670(ynfE) APECO1_671(ynfF)
ECOA : APECO78_11735 APECO78_11740 APECO78_18105
ECX : EcHS_A1660(ynfE) EcHS_A1661 EcHS_A3038
ECM : EcSMS35_1613(ynfE) EcSMS35_3011
ECY : ECSE_1708 ECSE_1709 ECSE_3142
ECR : ECIAI1_1637(ynfE) ECIAI1_1638(ynfF) ECIAI1_2998(ygfK)
ECQ : ECED1_1757(ynfF) ECED1_3338(ygfK)
EUM : ECUMN_1872(ynfE) ECUMN_1873(ynfF) ECUMN_3221(ygfK)
ECT : ECIAI39_1470(ynfF) ECIAI39_1471(ynfE) ECIAI39_3293(ygfK)
EOC : CE10_1857(ynfE) CE10_1858(ynfF) CE10_3317(ygfK)
EBR : ECB_01556(ynfE) ECB_01557(ynfF) ECB_02711(ygfK)
ECOB : C3029_12280 C3029_12285 C3029_18320
EBL : ECD_01556(ynfE) ECD_01557(ynfF) ECD_02711(ygfK)
EBE : B21_01546(ynfE) B21_01547(ynfF) B21_02673(ygfK)
EBD : ECBD_0859 ECBD_2058 ECBD_2059
ECI : UTI89_C1774(ynfE) UTI89_C1775(ynfF) UTI89_C3263(ygfK)
EIH : ECOK1_1705 ECOK1_3264
ECZ : ECS88_1632(ynfE) ECS88_1633(ynfF) ECS88_3157(ygfK)
ECC : c1977(ynfE) c1978(ynfF) c3456(ygfK)
ELO : EC042_1734 EC042_1735 EC042_3089
ELN : NRG857_07945 NRG857_14125
ECL : EcolC_0830 EcolC_2042 EcolC_2043
EKO : EKO11_0853 EKO11_2190 EKO11_2191
EKF : KO11_08375(ygfK) KO11_14815(ynfF) KO11_14820(ynfE)
EAB : ECABU_c17830(ynfE) ECABU_c17840(ynfF) ECABU_c31590(ygfK)
EDH : EcDH1_0814 EcDH1_2055 EcDH1_2056
EDJ : ECDH1ME8569_1530(ynfE) ECDH1ME8569_1531(ynfF) ECDH1ME8569_2781(ygfK)
ELU : UM146_02130 UM146_09225
ELW : ECW_m1752(ynfE) ECW_m1753(ynfF) ECW_m3131(ygfK)
ELL : WFL_08580(ynfE) WFL_08585(ynfF) WFL_15290(ygfK)
ELC : i14_1800(ynfE) i14_1801(ynfF) i14_3175(ygfK)
ELD : i02_1800(ynfE) i02_1801(ynfF) i02_3175(ygfK)
ELP : P12B_c1493(ynfF) P12B_c2976
ELF : LF82_3172(ygfK) LF82_3571(ynfE)
ECOL : LY180_08265 LY180_08270 LY180_14810
ECOI : ECOPMV1_01682(dmsA_2) ECOPMV1_01683(dmsA_3) ECOPMV1_03150(gltD_2)
ECOJ : P423_08500 P423_15800
EAL : EAKF1_ch3128c EAKF1_ch4465c EAKF1_ch4466c(ynfE)
STY : STY1565(dmsA1) STY1566(dmsA2)
STT : t1419(dmsA) t1420(dmsA)
SEX : STBHUCCB_15050 STBHUCCB_15060
SENT : TY21A_07180 TY21A_07185
SEO : STM14_1809 STM14_1811
SEV : STMMW_14981 STMMW_14991
SEY : SL1344_1428(dmsA2) SL1344_1429(dmsA1)
SEM : STMDT12_C15120 STMDT12_C15130
SEJ : STMUK_1461 STMUK_1462
SEB : STM474_1508(ynff) STM474_1509(ynfe)
SEF : UMN798_1561(dmsA2) UMN798_1562(dmsA1)
SETU : STU288_03805 STU288_03810
SETC : CFSAN001921_09635 CFSAN001921_09640
SENR : STMDT2_14251(dmsA2) STMDT2_14261(dmsA1)
SEND : DT104_14681(dmsA2) DT104_14691(dmsA1)
SENI : CY43_07630 CY43_07635
SPQ : SPAB_01812 SPAB_01813
SEI : SPC_2230(dmsA1) SPC_2231(dmsA2)
SEC : SCH_1515(ynfF) SCH_1516(ynfE)
SEH : SeHA_C1668 SeHA_C1669
SENH : CFSAN002069_01500 CFSAN002069_01505
SEEH : SEEH1578_16710 SEEH1578_16715
SEE : SNSL254_A1609 SNSL254_A1610
SENN : SN31241_25690 SN31241_25700
SEW : SeSA_A1600 SeSA_A1601
SEA : SeAg_B1673 SeAg_B1674
SENS : Q786_07750 Q786_07755
SEGA : SPUCDC_1314 SPUCDC_1315(dmsA1)
SET : SEN1551(dmsA1) SEN1552(dmsA3)
SENA : AU38_08015 AU38_08020
SENO : AU37_08015 AU37_08020
SENV : AU39_08025 AU39_08030
SENQ : AU40_08975 AU40_08980
SENL : IY59_08210 IY59_08215
SENJ : CFSAN001992_04085 CFSAN001992_04090
SEEB : SEEB0189_012030 SEEB0189_012035
SEEP : I137_06085 I137_06090
SENB : BN855_15380 BN855_15390
SENE : IA1_07410 IA1_07415
SENC : SEET0819_14155 SEET0819_14160
SBG : SBG_1325(dmsA2) SBG_1326(dmsA1)
SBV : N643_06340 N643_06345
SALZ : EOS98_11945 EOS98_11950
SBC : SbBS512_E1773(ynfE) SbBS512_E1774(arnT)
SHQ : A0259_11955 A0259_11960 A0259_17950
KOY : J415_14360 J415_16035
KOM : HR38_19850 HR38_21590
KOK : KONIH1_15600 KONIH1_17330
KOC : AB185_18570 AB185_20295
KLW : DA718_04840(ygfK) DA718_13525
KPAS : LUW96_22300 LUW96_23940(ygfK)
KLC : K7H21_11170(ygfK) K7H21_12965
KLM : BWI76_15925 BWI76_17535
REE : electrica_02374(ynfE)
ROR : RORB6_04785 RORB6_05570
RON : TE10_15670 TE10_16775
RPLN : B1209_11435 B1209_12240
RAO : DSD31_11215 DSD31_12045
RTG : NCTC13098_03248(preT)
CBRA : A6J81_03910 A6J81_03915
CAMA : F384_06775 F384_12845 F384_15880
CFAR : CI104_12720 CI104_20945
CIR : C2U53_14060 C2U53_21880
CTEL : GBC03_08860(ygfK) GBC03_17830
CENS : P2W74_04055(ygfK) P2W74_12415
CNT : JT31_01270 JT31_02335
CLAP : NCTC11466_02405(dmsA_1)
PGE : LG71_13830 LG71_16420
ESC : Entcl_2330 Entcl_2792 Entcl_2892
KLE : AO703_08230 AO703_10575
KCO : BWI95_15805 BWI95_21360
KOT : EH164_06780(ygfK) EH164_12185
KOB : HF650_10910 HF650_16560(ygfK)
KLU : K7B04_17595(ygfK) K7B04_17855
BUF : D8682_01175 D8682_26450
BFT : MNO13_13925 MNO13_15720(ygfK)
BSEL : RHD99_11950(ygfK) RHD99_12825(ynfE)
AHN : NCTC12129_04060(gltD_1)
YRE : HEC60_05820 HEC60_20655(ygfK)
IZH : FEM41_07430(ygfK) FEM41_16975
PSGC : G163CM_12830(ynfE) G163CM_12840(ynfF)
SFW : WN53_17730 WN53_18685 WN53_18785
SFG : AV650_13200 AV650_13950 AV650_14015
SFO : Z042_01830 Z042_06485
MINT : C7M51_04190(sfrB_2)
HAV : AT03_02475 AT03_19930
HPAR : AL518_03105 AL518_06620
OPO : DSM2777_01560 DSM2777_05495
ALIG : NCTC10568_02039(dmsA)
PAET : NCTC13378_00876(dmsA_1)
ADN : Alide_4611 Alide_4613 Alide_4614
IDC : LRM40_18950 LRM40_18955 LRM40_18965
BPRO : PMF13cell1_03284(gltD_2)
BLUI : Blut17040_19720(ygfK)
CSCI : HDCHBGLK_02487(sfrB_2)
MTHO : MOTHE_c19880(gltD2)
MTHZ : MOTHA_c20670(gltD2)
MANA : MAMMFC1_01252(preT)
EGD : GS424_002435 GS424_015465
BWA : HLV38_05600 HLV38_06290
OCK : EXM22_00735(ygfK) EXM22_08295(ygfK)
MSIL : METEAL_21340 METEAL_41020
BLQ : L21SP5_02724(gltD_4)
» show all
Taxonomy
Reference
Authors
Macy JM, Rech S, Auling G, Dorsch M, Stackebrandt E, Sly LI.
Title
Thauera selenatis gen. nov., sp. nov., a member of the beta subclass of Proteobacteria with a novel type of anaerobic respiration.
Journal
Reference
Authors
Schroder I, Rech S, Krafft T, Macy JM
Title
Purification and characterization of the selenate reductase from Thauera selenatis.
Journal
Sequence
Reference
Authors
Stolz JF, Oremland RS.
Title
Bacterial respiration of arsenic and selenium.
Journal
Reference
Authors
Krafft T, Bowen A, Theis F, Macy JM
Title
Cloning and sequencing of the genes encoding the periplasmic-cytochrome B-containing selenate reductase of Thauera selenatis.
Journal
Sequence
Reference
Authors
Maher MJ, Macy JM.
Title
Crystallization and preliminary X-ray analysis of the selenate reductase from Thauera selenatis.
Journal
Reference
Authors
Maher MJ, Santini J, Pickering IJ, Prince RC, Macy JM, George GN.
Title
X-ray absorption spectroscopy of selenate reductase.
Journal
Reference
Authors
Lowe EC, Bydder S, Hartshorne RS, Tape HL, Dridge EJ, Debieux CM, Paszkiewicz K, Singleton I, Lewis RJ, Santini JM, Richardson DJ, Butler CS.
Title
Quinol-cytochrome c oxidoreductase and cytochrome c4 mediate electron transfer during selenate respiration in Thauera selenatis.
Journal
Other DBs
ExplorEnz - The Enzyme Database: 1.97.1.9
ExPASy - ENZYME nomenclature database: 1.97.1.9
LinkDB
All DBs