KEGG ENZYME: 2.1.1.103

ENZYME: 2.1.1.103

Entry

EC 2.1.1.103                Enzyme

Name

phosphoethanolamine N-methyltransferase;
phosphoethanolamine methyltransferase

Class

Transferases;
Transferring one-carbon groups;
Methyltransferases

Sysname

S-adenosyl-L-methionine:ethanolamine-phosphate N-methyltransferase

Reaction(IUBMB)

S-adenosyl-L-methionine + ethanolamine phosphate = S-adenosyl-L-homocysteine + N-methylethanolamine phosphate [RN:R02037]

Reaction(KEGG)

R02037;
(other) R06868 R06869

Substrate

S-adenosyl-L-methionine [CPD:C00019];
ethanolamine phosphate [CPD:C00346]

Product

S-adenosyl-L-homocysteine [CPD:C00021];
N-methylethanolamine phosphate [CPD:C01210]

Comment

The enzyme may catalyse the transfer of two further methyl groups to the product.

History

EC 2.1.1.103 created 1992

Pathway

ec00564

Glycerophospholipid metabolism

Orthology

K05929

phosphoethanolamine N-methyltransferase

Genes

AJM:

119043483

ASAO:

132764257

PVT:

110091757

SUND:

121916279

PBI:

103062247

PMUR:

107297105

CTIG:

120318487

TSR:

106556196

APRI:

131186578

PTEX:

113446675

NSS:

113425423

VKO:

123032548

PMUA:

114586552

PRAF:

128403677(RIN1)

ZVI:	118075874(RIN1)

HCG:

128337138

GJA:

107121086

STOW:

125439715

EMC:

129332271

XLA:	108713951(pmt.L) 447061(pmt.S)

XTR:	100124841(pmt100124841)

NPR:

108784145

RTEM:

120917521

BBUF:

120981206

BGAR:

122920736

MUO:

115479952

GSH:

117365847

DRE:	767699(pmt)

SRX:	107729321 107731361

SANH:

107662165 107704645

SGH:	107552346 107596343

CCAR:

109082187 109094243

CAUA:

113113813

CGIB:

127971835

PTET:

122357636 122357637 122357638

LROH:

127175887(pmt)

OMC:	131553030 131553031

PPRM:

120465290(pmt) 120465291

RKG:	130072083(pmt) 130072084

MAMB:

125266847(pmt) 125266848

CIDE:

127494336

CERY:

137024312(pmt)

MASI:

127413219 127418090

TROS:

130563378(pmt)

TDW:	130437802(pmt)

MANU:

129422452(pmt)

IPU:	108275150(pmt)

IFU:	128618241(pmt)

PHYP:

113529998

SMEO:

124392304(pmt)

TFD:	113660046(pmt)

TVC:	132856766(pmt)

TRN:	134309216(pmt)

AMEX:

103035546(pmt)

CMAO:

118811501(pmt)

EEE:

113577142

CHAR:

105903574(pmt)

TRU:

101075688

TFS:	130530992 130531151

TNG:	GSTEN00031142G001

LCO:

104919993

NCC:

104950073

TBEN:

117488236(pmt)

CGOB:

115014777

PGEO:

117454441(pmt)

GACU:

117555809 117555810

EMAC:

134859802(pmt)

ELY:	117253596(pmt)

EFO:	125894551(pmt)

PLEP:

121947644(pmt)

SLUC:

116052526 116052622

ECRA:

117952116(pmt)

ESP:

116696484

PFLV:

114562973 114563389

GAT:	120818402(pmt)

PPUG:

119210595(pmt)

AFB:	129090267(pmt)

CLUM:

117737411(pmt)

PSWI:

130209475(pmt)

MSAM:

119888300(pmt) 119888734

SCHU:

122880275(pmt)

CUD:	121516029(pmt)

ALAT:

119007183(pmt)

MZE:

101475026

ONL:

100710232

OAU:	116330335(pmt)

OLA:

101161165

OML:	112153430(pmt)

CSAI:

133447598(pmt)

XMA:

102222707

XCO:

114138663

XHE:

116713898

PRET:

103471399

PFOR:

103136915

PLAI:

106945197

PMEI:

106930518

GAF:	122836935(pmt)

PPRL:

129362895(pmt)

CVG:

107090983

CTUL:

119784482(pmt)

GMU:	124859867(pmt)

NFU:

107377225

KMR:	108246673(pmt)

ALIM:

106516171

NWH:	119408432(pmt)

AOCE:

111571370

MCEP:

125008337(pmt)

CSEM:

103390730

POV:

109630475

SSEN:

122778536(pmt)

HHIP:

117769612(pmt)

HSP:	118112763(pmt)

PPLT:

128445425(pmt)

SMAU:

118319592(pmt)

LCF:	108899095(pmt)

SDU:

111232752

SLAL:

111655797

XGL:	120785755(pmt)

HCQ:

109524230

SSCV:

125981330

SBIA:

133508398(pmt)

PEE:	133407849(pmt)

PTAO:

133485106(pmt)

BPEC:

110158954

MALB:

109955401

BSPL:

114864457 114864458

SJO:	128362607(pmt)

SASA:

100380594(peam3)

STRU:

115166946 115205744

OTW:	112236062 112247711

OMY:	110489193 110504479

OGO:	123993748 124010355

ONE:	115121095 115125787

OKI:	109865015 109878040

OKE:	118372832 118373297

SALP:

111965593 112077161

SNH:	120047867(pmt)

CCLU:

121538507 121587524

ELS:

105007573

SFM:

108923708

PKI:

111851977

AANG:

118223416 118223417

LOC:

107075359

PSPA:

121310077(pmt)

ARUT:

117398653 117962524

PSEX:

120539278(pmt)

LCM:

102349382

HOC:	132836176(pmt)

PMRN:

116939643 116943248

LRJ:	133342352 133346895

BFO:	118418310 118418317 118418406

BBEL:

109482118 109482139

CIN:

113475139

SCLV:

120334118

SPU:

589652

LPIC:

129268806

APLC:

110983059

ARUN:

117289074

AJC:	117117381 117117419

RZE:	108353900 108354084

BCOO:

119074418

MSEX:

115454195

ATRA:

106129845 106129846 106129915

FCD:	110846430 110846434

DPX:	DAPPUDRAFT_58148

DMK:

116930291

DPZ:

124346936

PVM:	113802189 113813719 113819959 113819960 113822659 113830072

PJA:	122244706 122244714

PCHN:

125041253 125041260 125041471 125041474

PMOO:

119591648

HAME:

121870016 121870022 121870024 121870025

PCLA:

123746079 123746080

CQD:	128685101 128685102 128685104 128703144

PTRU:

123505386 123505573

ESN:	127001513 127001605 127001606

MNZ:	135203769 135205706 135205707

HAZT:

108679834

EAF:

111696920

TCF:	131878844 131891974

PPOI:

119098230

DSV:

119460907

RSAN:

119396650

RMP:

119173940

DPTE:

113790454

DFR:

124492235

CSCU:

111633391

CVS:

136971101

PTEP:

107440289

ABRU:

129963707

UDV:

129220424

SDM:

118187330

PMEO:

129598043 129601378

CEL:	CELE_F54D11.1(pmt-2)

CBR:	CBG_08775(Cbr-pmt-2)

CRQ:	GCK72_019288

NAI:	NECAME_07669 NECAME_17349

HRO:	HELRODRAFT_183893

LGI:	LOTGIDRAFT_219756

PVUL:

126815505

PCAN:

112576882

BGT:	106063257 106067231 106069080

GAE:

121389007

HRF:	124116865 124138938

HRJ:	124254267 124262648

CRG:

105346608

CANU:

128188234

CVN:

111133025

OED:

130047309

MYI:	110467500 110467501

PMAX:

117337331 117337662

MCAF:

127703188

MMER:

123548662

RPHI:

132749130

DPOL:

127844234 127844849

MAEA:

128244694

LJP:	135475181 135475355

LAK:	106152432 106159440 106167686

LLON:

135492727 135496243 135502154 135502155

NVE:

5514599

EPA:

110238903

ATEN:

116287999

ADF:

107345655

AMIL:

114954163 114961064

PDAM:

113680704 113685456 113685457

SPIS:

111333402 111337027

DGT:	114516779 114520320

XEN:	124436420 124442907

AQU:

105312480

ATH:	AT1G48600(PMEAMT) AT1G73600 AT3G18000(XPL1)

ALY:	9319166 9324999 9327507

CRB:	111828740 17890856 17894561 17897253 17897616 17897963

CSAT:

104702057 104712972 104742380 104742436 104746158 104751212 104759843 104765652 104777780 104782866

EUS:	EUTSA_v10011451mg EUTSA_v10012068mg EUTSA_v10018431mg EUTSA_v10020595mg

BRP:	103830744 103869623 103871458

BNA:	106422521 106447056 106452046 111199272 111203757 111216226 125608989

BOE:	106296857 106300935 106343424

RSZ:	108805391 108814299 108839561 108862712

THJ:	104798729 104809626 104814039

CPAP:

110823096

CIT:

102621248

CIC:	CICLE_v10010749mg

MINC:

123196963 123204213

TCC:

18604331

GRA:	105765669 105794081

GHI:	107887176 107908485 107931051 107944617

GAB:	108457077 108476664

HSYR:

120117297 120166107 120178803 120185030

DZI:	111282113 111317013

EGR:

104422958

GMX:	100808891 100818466 100820554

GSJ:	114368773 114413737 114418788

PVU:	PHAVU_002G330400g PHAVU_004G150500g

VRA:	106771134 106773900

VAR:	108334093 108343874

VUN:	114175128 114182131

VUM:	124821540 124847970 124847971

CCAJ:

109799470 109799837

APRC:

113854878 113867626

MTR:	11409633 11415048

TPRA:

123913844 123914041

CAM:	101492157 101494817

PSAT:

127104947 127108021

VVO:	131598763 131598773 131603952

LJA:	130716120 130738786

ADU:	107481885 107490634

AIP:	107631749 107644191

AHF:	112734267 112750986 112792102 112802332

LANG:

109331700 109349676

PCIN:

129319465

QSA:	O6P43_005184 O6P43_005185 O6P43_008482

FVE:

101308287

RCN:

112175261

PPER:

18775666

PMUM:

103338698

PAVI:

110745463

PDUL:

117628111

MDM:	103428324 103455627

MSYL:

126598789 126626484

PXB:	103946940 103950575

ZJU:

107418540

MNT:	21400374 21400376

CSAV:

115709566 115709567

CSV:	101219872 101220267 101220498

CMO:	103494180(7G07) 103502109

BHJ:	120070690 120072227 120083479

MCHA:

111006846 111008557

CMAX:

111490074 111495344 111497230

CMOS:

111431339 111432905 111457159

CPEP:

111783041 111793745 111801506

RCU:

8286323

MEAN:

126667689

JCU:	105647160 105647162

HBR:	110637755 110647788

MESC:

110617683 110631070

POP:	7462495 7486728

PEU:	105114088 105117969 105135790

PALZ:

118051013 118051014

PNZ:	133675563 133678568

JRE:	108986188 109020045 118348763

CILL:

122296278 122299701

CAVE:

132183824 132184016

QSU:

111993321

QLO:

115963408

TWL:	119981520 119987436

VVI:	100254279 100257695 100266279

VRI:	117904431 117910655 117924788

SLY:	101246730 101247110 543681

SPEN:

107007227 107015294 107023864

SOT:	102587578 102596533 102597155

SSTN:

125860231 125863258 125874631

SDUL:

129893249 129895281 129901527

CANN:

107851484 107854150 107855422 107855425

LBB:	132599742 132603585 132633203

NTA:	107763430 107768744 107780089 107788559 107800284 107812762

NSY:	104210219 104226203 104231001

NTO:	104092140 104107697 104109150

NAU:	109219394 109223801 109237405

INI:	109150242 109165441

ITR:	116012621 116032639

SIND:

105158067 105166538

OEU:	111372321 111405233

EGT:	105961810 105972797

SSPL:

121749581 121752347

SMIL:

130990261 130990262

SHIS:

125188971

APAN:

127241061 127243366

HAN:	110865567 110908410

ECAD:

122605280 122605975

LSV:

111882643

CCAV:

112523504

DCR:

108218638

CSIN:

114264680

RVL:

131309745

AEW:	130755058 130761482

BVG:	104893012 104893682 104900778

SOE:	110779155 110791740

CQI:	110683223 110710093 110716555 110730138 110732587

ATRI:

130797582 130801590

MOF:

131145450

NNU:	104601850 104609969

MING:

122078831

TSS:

122646212

PSOM:

113275535 113275537 113282074

OSA:	4323890 4339516

OBR:	102712945 102718369

OGL:	127758309 127773832

BDI:	100828194 100841832

ATS:	109755056 109781493

TDC:	119268738 119276678 119289765 119349328

TAES:

100415866 123065943 123070489 123078907 123143439 123174906 123182886 543067

TUA:

125544470

LPER:

127327430 127343453

LRD:	124660791 124666224 124707189

SBI:	8063104 8063105 8069007

ZMA:	100282545 100383478 103651303

MFLO:

136452764 136452856 136513784 136514899 136518210 136533620

SITA:

101754563 101784345 101784745

SVS:	117848691 117854984 117854985

PVIR:

120675331 120675434 120697945 120707712 120707713

PHAI:

112885726 112894873 112895645

PDA:	103713941 103713971

EGU:	105044829 105044847

MUS:	103972761 103987477

ZOF:	121992680 121996639 122025504

DCT:

110116577

PEQ:

110019093

AOF:	109840721 109847594

MSIN:

131251279

NCOL:

116249237 116264206

ATR:

18433651

SMO:	SELMODRAFT_146547 SELMODRAFT_270875

PPP:

112280978

MNG:

MNEG_7307

CSL:	COCSUDRAFT_19591

APRO:

F751_5852

PFA:	PF3D7_1343000

PFH:	PFHG_02129

PREI:

PRSY57_1342000

PGAB:

PGSY75_1343000

PLAG:

39743667(PADL01_1342100)

PKN:	PKNH_1258400

PVX:	PVX_083045

PCY:	PCYB_122070

PMAL:

PMUG01_12021900

PBRS:

92372245(MKS88_004158)

PREL:

PRELSG_1254900(PMT)

PCOT:

PCOAH_00041600

TGO:	TGME49_293830

NGD:	NGA_0675600

PIF:	PITG_15903 PITG_15904

PSOJ:

PHYSODRAFT_345888 PHYSODRAFT_354467

SPAR:

SPRG_15850 SPRG_15851

BGL:	bglu_2g17550

BGU:

KS03_4174

BGP:	BGL_2c23470

BPLA:

bpln_2g23750

PLH:	VT85_04350

IPA:

Isop_0820

SACI:

Sinac_7015

PBOR:

BSF38_02385(rebM_4)

AGV:	OJF2_26770

» show all

Reference

1 [PMID:16666464]

Authors

Datko AH, Mudd SH.

Title

Enzymes of Phosphatidylcholine Synthesis in Lemna, Soybean, and Carrot.

Journal

Plant Physiol 88:1338-1348 (1988)
DOI:10.1104/pp.88.4.1338

Other DBs

ExplorEnz - The Enzyme Database:

2.1.1.103

IUBMB Enzyme Nomenclature:

2.1.1.103

ExPASy - ENZYME nomenclature database:

2.1.1.103

BRENDA, the Enzyme Database:

2.1.1.103

CAS:	171040-79-2

LinkDB

DBGET integrated database retrieval system