| Entry |
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| Name |
10-hydroxydihydrosanguinarine 10-O-methyltransferase
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| Class |
Transferases;
Transferring one-carbon groups;
Methyltransferases
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| Sysname |
S-adenosyl-L-methionine:10-hydroxydihydrosanguinarine 10-O-methyltransferase
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| Reaction(IUBMB) |
S-adenosyl-L-methionine + 10-hydroxydihydrosanguinarine = S-adenosyl-L-homocysteine + dihydrochelirubine [RN: R04707]
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| Reaction(KEGG) |
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| Substrate |
S-adenosyl-L-methionine [CPD: C00019];
10-hydroxydihydrosanguinarine [CPD: C05247]
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| Product |
S-adenosyl-L-homocysteine [CPD: C00021];
dihydrochelirubine [CPD: C05194]
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| Comment |
This reaction is part of the pathway for synthesis of benzophenanthridine alkaloids in plants.
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| History |
EC 2.1.1.119 created 1999
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| Pathway |
| ec00950 | Isoquinoline alkaloid biosynthesis |
| ec01110 | Biosynthesis of secondary metabolites |
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| Reference |
1 |
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| Authors |
De-Eknamkul W, Tanahashi T, Zenk MH. |
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| Title |
Enzymic 10-hydroxylation and 10-O-methylation of dihydrosanguinarine in dihydrochelirubine formation by Eschscholtzia. |
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| Journal |
Phytochemistry 31:2713-2717 (1992) |
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| Other DBs |
| ExPASy - ENZYME nomenclature database: | 2.1.1.119 |
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| LinkDB |
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