KEGG   ENZYME: 2.3.1.242
Entry
EC 2.3.1.242                Enzyme                                 
Name
Kdo2-lipid IVA palmitoleoyltransferase;
LpxP;
palmitoleoyl-acyl carrier protein-dependent acyltransferase;
cold-induced palmitoleoyl transferase;
palmitoleoyl-[acyl-carrier protein]:Kdo2-lipid IVA O-palmitoleoyltransferase;
(Kdo)2-lipid IVA palmitoleoyltransferase;
alpha-Kdo-(2->4)-alpha-(2->6)-lipid IVA palmitoleoyltransferase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
Sysname
(9Z)-hexadec-9-enoyl-[acyl-carrier protein]:Kdo2-lipid IVA O-palmitoleoyltransferase
Reaction(IUBMB)
a (9Z)-hexadec-9-enoyl-[acyl-carrier protein] + Kdo2-lipid IVA = (9Z)-hexadec-9-enoyl-Kdo2-lipid IVA + an [acyl-carrier protein] [RN:R10906]
Reaction(KEGG)
R10906
Substrate
(9Z)-hexadec-9-enoyl-[acyl-carrier protein] [CPD:C16520];
Kdo2-lipid IVA [CPD:C06025]
Product
(9Z)-hexadec-9-enoyl-Kdo2-lipid IVA [CPD:C20933];
[acyl-carrier protein] [CPD:C00229]
Comment
The enzyme, characterized from the bacterium Escherichia coli, is induced upon cold shock and is involved in the formation of a cold-adapted variant of the outer membrane glycolipid lipid A.
History
EC 2.3.1.242 created 2014
Pathway
ec00540  Lipopolysaccharide biosynthesis
Orthology
K12974  KDO2-lipid IV(A) palmitoleoyltransferase
Genes
ECOb2378(lpxP)
ECJJW2375(ddg)
ECDECDH10B_2543(lpxP)
EBWBWG_2146(lpxP)
ECOKECMDS42_1935(ddg)
ECEZ3643(ddg)
ECSECs_3258(lpxP)
ECFECH74115_3609
ETWECSP_3327(lpxP)
ELXCDCO157_3022
EOIECO111_3114(ddg)
EOJECO26_3438(ddg)
EOHECO103_2903(ddg)
ECOOECRM13514_3202(ddg)
ECOHECRM13516_3064(ddg)
ESLO3K_07480
ESOO3O_18155
ESMO3M_07530
ECKEC55989_2674(ddg)
ECGE2348C_2571(lpxP)
EOKG2583_2911(lpxP)
ELRECO55CA74_14440
ELHETEC_2497
ECWEcE24377A_2666
EUNUMNK88_2976
ECPECP_2404
ENAECNA114_2459(ddg)
ECOSEC958_4999
ECVAPECO1_4159(ddg)
ECOAAPECO78_15645
ECXEcHS_A2514
ECMEcSMS35_2529
ECYECSE_2675
ECRECIAI1_2444(ddg)
ECQECED1_2825(ddg)
EUMECUMN_2708(ddg)
ECTECIAI39_2522(ddg)
EOCCE10_2755(lpxP)
EBRECB_02288(ddg)
EBLECD_02288(lpxP)
EBEB21_02249(lpxP)
EBDECBD_1294
ECIUTI89_C2710(ddg)
EIHECOK1_2694
ECZECS88_2573(ddg)
ECCc2915(ddg)
ELOEC042_2597(lpxP)
ELNNRG857_11950
ESEECSF_2248
ECLEcolC_1291
EKOEKO11_1340
EKFKO11_10870(lpxP)
EABECABU_c26980
EDHEcDH1_1279
EDJECDH1ME8569_2317(ddg)
ELUUM146_04710
ELWECW_m2611(lpxP)
ELLWFL_12810(lpxP)
ELCi14_2712(ddg)
ELDi02_2712(ddg)
ELPP12B_c2496
ELFLF82_1232(lpxP)
ECOLLY180_12260
ECOIECOPMV1_02582(htrB_2)
ECOJP423_13220
EFEEFER_0790(ddg)
EALEAKF1_ch3621c
EMAC1192_23570
ESZFEM44_01935(lpxP)
STYSTY2639
STTt0457
SEXSTBHUCCB_4920
SENTTY21A_02330
STMSTM2401(ddg)
SEOSTM14_2953(ddg)
SEVSTMMW_24241
SEYSL1344_2369(lpxP)
SEMSTMDT12_C24240
SEJSTMUK_2432(ddg)
SEBSTM474_2501(ddg)
SEFUMN798_2592
SETUSTU288_08395
SETCCFSAN001921_04770
SENRSTMDT2_23691
SENDDT104_24581
SENICY43_12850
SEENSE451236_18220
SPTSPA0459(ddg)
SEKSSPA0426
SPQSPAB_00561
SEISPC_1256(ddg)
SECSCH_2402(ddg)
SENHCFSAN002069_19770
SEEHSEEH1578_21340
SENNSN31241_35100
SENSQ786_11860
SEGSG2437(ddg)
SELSPUL_0478(ddg)
SEGASPUCDC_0478(ddg)
SETSEN2387(ddg)
SENAAU38_12080
SENOAU37_12095
SENVAU39_12095
SENQAU40_13540
SENLIY59_12415
SENJCFSAN001992_21580
SEECCFSAN002050_18945
SEEBSEEB0189_007560
SEEPI137_02185
SENBBN855_24890
SENEIA1_11985
SENCSEET0819_19450
SESSARI_00489
SBGSBG_2203
SBZA464_2528
SBVN643_10670
SALZEOS98_07000
SFLSF2444(ddg)
SFXS2582(ddg)
SFVSFV_2436(ddg)
SFESFxv_2690(lpxP)
SFNSFy_3466
SFSSFyv_3541
SFTNCTC1_02681(ddg)
SSNSSON_2469(ddg)
SBOSBO_2404(ddg)
SBCSbBS512_E2746
SDYSDY_2576(ddg)
SDZAsd1617_03471
SHQA0259_15645
ENCECL_03721
ENLA3UG_16330
ECLGEC036_31780
ECLEECNIH2_16305
ECLNECNIH4_06850
ECLIECNIH5_15240
ECLXLI66_15645
ECLYLI62_17145
ECLZLI64_15075
EHMAB284_09775
EXFBFV63_15465
ECLAECNIH3_15335
ECLCECR091_15270
EAUDI57_03325
EKBBFV64_16010
ENOECENHK_15900
EECEcWSU1_03221(lpxP)
ELGBH714_12245 BH714_17305
ECANCWI88_06455
ERNBFV67_15785
ECLSLI67_017170
ECHGFY206_17635(lpxP)
ESHC1N69_16155
ENTEnt638_2917
EASEntas_3123
ENRH650_04190
ENXNI40_009845 NI40_015920
ENFAKI40_2835
LNICWR52_19125
EBGFAI37_13170(lpxP)
ENDA4308_20560
ENZG0034_16510(lpxP)
ENSHWQ15_01225(lpxP)
ENKLOC22_03785(lpxP)
EHUD5067_0006845(lpxP)
EMORL6Y89_15465(lpxP)
ESAESA_02951
CSKES15_3030(lpxP)
CSZCSSP291_14045
CSJCSK29544_04229
CCONAFK62_04695
CDMAFK67_04645
CSIP262_04376
CMJAFK66_015090
CUIAFK65_04615
CMWAFK63_13990
CTUCTU_09250(ddg)
KPNKPN_01167
KPUKP1_2185
KPMKPHS_20470
KPPA79E_3023
KPHKPNIH24_18350
KPZKPNIH27_10030
KPVKPNIH29_10540
KPWKPNIH30_10725
KPYKPNIH31_10155
KPGKPNIH32_10565
KPCKPNIH10_10180
KPQKPR0928_10350
KPTVK055_1295(lpxL)
KPOKPN2242_08945
KPRKPR_2210 KPR_2211
KPJN559_3127
KPID364_06060
KPAKPNJ1_03359
KPSKPNJ2_03351
KPXPMK1_03505(htrB_3)
KPBFH42_01645
KPNEKU54_015935
KPNULI86_16245
KPNKBN49_2301
KVAKvar_3191
KPEKPK_3319 KPK_4958(lpxL)
KPKA593_20375 A593_25930
KVDKR75_18225 KR75_27095
KVQSP68_24685
KOXKOX_02260 KOX_17880
KOEA225_2433
KOYJ415_19915
KOMHR38_16170
KMIVW41_04510
KOKKONIH1_11675
KOCAB185_24520
KQUAVR78_15160
EAEEAE_20940 EAE_21810
EARCCG29572
KQVB8P98_16545
KLLBJF97_12270
KLWDA718_16845
KARLGL98_15365(lpxP)
KGRJJJ10_16855(lpxP)
RORRORB6_08800
RONTE10_11765
RPLNB1209_16180
RAODSD31_15385
RTGNCTC13098_04341(htrB_1)
REEelectrica_03052(htrB_1)
CROROD_27921(lpxP)
CKOCKO_00422
CFDCFNIH1_23325
CBRAA6J81_24460
CWECO701_05975
CYOCD187_07375 CD187_18990
CPOTFOB25_18540(lpxP)
CFQC2U38_17625
CSEDJY391_07110(lpxP)
CAMAF384_13225
CAFAL524_10215
CIFAL515_16195
CFARCI104_17940
CIRC2U53_28170
CIEAN232_11825
CPARCUC49_12255
CTELGBC03_12085(lpxP) GBC03_19165(lpxP)
CITZE4Z61_00660(lpxP)
CARSE1B03_18840(lpxP)
EBTEBL_c23630
CNTJT31_07790
CEMLH23_09930
CENLH86_09990
CLAPNCTC11466_03588(htrB_2)
PGELG71_15375
ESCEntcl_2116
KLEAO703_11605
KSAC813_04810
KORAWR26_13805(lpxP) AWR26_14285(lpxP)
KRDA3780_09615 A3780_10085
KCOBWI95_15280 BWI95_22145
KOTEH164_12710
KPSEIP581_10025(lpxP)
KIENCTC12125_00960(htrB_1)
KASKATP_17780(lpxP)
LAXAPT61_06500
LEIC2U54_21535
LEHC3F35_18490
LEEDVA44_06615
LERGNG29_16145(lpxP)
LEAGNG26_15990(lpxP)
LPNUKQ929_05665(lpxP)
LAZA8A57_15025
LEFLJPFL01_2962
LEWDAI21_11630
BUFD8682_10695
BAGEBADSM9389_32830
BFTMNO13_19360(lpxP)
SYMK6K13_10925(lpxP)
METYMRY16398_23250(lpxP)
AHNNCTC12129_02526(ddg)
ASUBNLZ15_10825(lpxP)
YREHEC60_07835(lpxP)
SGOEA8O29_010270(lpxP)
KINAB182_10360
PDZHHA33_12995(lpxP)
IZHFEM41_10605(lpxP)
PSGCG163CM_08290(lpxP)
EBFD782_1803
EBCC2U52_20950
EBUCUC76_05125
PSTSE05_06240
YPEYPO3632(ddg)
YPKy0236(ddg)
YPHYPC_4380
YPAYPA_3645
YPNYPN_3538
YPMYP_3915(ddg)
YPPYPDSF_0239
YPGYpAngola_A1232(htrB2)
YPZYPZ3_3121
YPTA1122_07575
YPDYPD4_3109
YPXYPD8_3216
YPWCH59_2387(lpxL)
YPJCH55_2569(lpxL)
YPVBZ15_4076(lpxL)
YPLCH46_1427(lpxL)
YPSYPTB3597(ddg)
YPOBZ17_3003(lpxL)
YPIYpsIP31758_0361(htrB2)
YPYYPK_0430
YPBYPTS_3787
YPQDJ40_2816(lpxL)
YPUBZ21_2925(lpxL)
YPRBZ20_2517(lpxL)
YPCBZ23_3197(lpxL)
YPFBZ19_3062(lpxL)
YENYE3829(ddg)
YEPYE105_C3546
YEYY11_27341
YELLC20_00553
YEWCH47_3967(lpxL)
YETCH48_2072(lpxL)
YEFFORC2_0357
YEEYE5303_01031(ddg)
YSIBF17_05605
YALAT01_2110(lpxL)
YFRAW19_2837(lpxL)
YINCH53_2176(lpxL)
YKRCH54_2951(lpxL)
YROCH64_2252(lpxL)
YRUBD65_1562(lpxL)
YRBUGYR_08345
YAKACZ76_07110
YMADA391_01705
YHID5F51_20275
YCAF0T03_19730(lpxP)
YMOHRD69_03355(lpxP)
SMARSM39_3882(lpxP)
SMACSMDB11_3678(lpxP)
SMWSMWW4_v1c43920(lpxP)
SPESpro_4425
SRRSerAS9_4529
SRLSOD_c42360(lpxP)
SRYM621_23130
SPLYQ5A_023075(lpxP)
SRSSerAS12_4530
SRASerAS13_4530
SMAFD781_4156
SLQM495_22290
SERFL085_06260
SERSSERRSCBI_21205
SFWWN53_05280
SFGAV650_00640 AV650_27480
SRZAXX16_0993
SERASer39006_021495
SERQCWC46_21505
SERMCLM71_21365
SQUE4343_18655(lpxP)
SFJSAMEA4384070_4388(htrB_2)
SOFNCTC11214_02250(htrB_2)
SSURATE40_018470
SURIJ0X03_02160(lpxP)
SRHZFO014_12260(lpxP)
SENPKHA73_21415(lpxP)
SFOZ042_09485
RAHRahaq_4028
RACEJHW33_14465(lpxP)
RAQRahaq2_4132
RAAQ7S_20470
ROXBV494_18830
RVCJ9880_05605(lpxP)
GQUAWC35_13855 AWC35_16440
EAMEGXP68_18825(lpxP)
RBADH2866_09930(lpxP)
ECAECA0781(ddg)
PATREV46_03425
PATOGZ59_06870(ddg)
PCTPC1_0655
PCCPCC21_006860
PCVBCS7_03340 BCS7_13145
PWAPecwa_0886
PPARA8F97_14495
PECW5S_0778
PWSA7983_11860
PPOABJK05_20325
PBRAB5S52_18270
PPUJE2566_03825(lpxP)
PARII2D83_18380(lpxP)
PAQUDMB82_0003970(lpxP) DMB82_0007970(lpxL)
PVZOA04_07680(lpxP) OA04_16160(htrB)
PPAVLOZ86_04190(lpxP)
PQUIG609_003390(lpxP) IG609_007375(lpxL)
DDDDda3937_02265(ddg)
DZEDd1591_3380
DDCDd586_0679
DZCW909_03580
DSOA4U42_12655
CEDLH89_08750
DFNCVE23_03980
DDQDDI_0536
DAQDAQ1742_00767(lpxP)
DICDpoa569_003258(lpxP)
DDADd703_2121
BGJAWC36_03655 AWC36_14830
BRBEH207_02725 EH207_09780(lpxL)
BNGEH206_07420(lpxL) EH206_18385
BIZHC231_07655(lpxL) HC231_19725(lpxP)
LBQCKQ53_08380 CKQ53_11750
LPOPI6N93_10045(lpxL) I6N93_13480(lpxP)
SGLSG0784
SODSant_2836(lpxP)
PESSOPEG_1130(lpxP)
SLIGGTU79_07280(lpxP)
EAMEAMY_0267(ddg)
EAYEAM_3150(lpxP)
ETAETA_02550(ddg)
EPYEpC_02750(ddg)
EPREPYR_00286(ddg)
EBIEbC_40850(ddg)
ERJEJP617_14400(ddg)
EGEEM595_0412(lpxP)
EPECI789_20740
EHDERCIPSTX3056_445(lpxP)
ERWIGN242_02040(lpxP)
ETPLU633_03230(lpxP)
PAMPANA_3932(ddg)
PLFPANA5342_0120(ddg)
PAJPAJ_3135(ddg)
PAQPAGR_g0116
PVAPvag_3205(ddg)
PAGGAL522_04160
PAOPat9b_3918
KLNLH22_02680
PANTPSNIH1_05520
PANPPSNIH2_16235
PAGCBEE12_06490
PALHB1H58_05410
PANSFCN45_19180(lpxP)
PEYEE896_00555(lpxP)
PDISD8B20_17085
PERLAC65_15715(lpxP)
PGZC2E15_02330
PCDC2E16_02390
MINTC7M51_03962(lpxP)
MTHIC7M52_03071(lpxP)
TCIA7K98_02265
TPTYNCTC11468_00494(htrB_2)
PMRPMI0808(ddg)
PMIBBB2000_0876(ddg)
PVLAOB99_06475
PVGCRN77_15535
PHAUPH4a_13370
PROTBTA34_05135
PCOLF1325_06750(lpxL)
PCIBF9282_06500(lpxL)
PPEEI6G31_03155(lpxL)
PSIS70_04395
PSXDR96_55(lpxL)
PSTABGK56_07600
PRGRB151_026350(htrB_2)
PRQCYG50_02890(lpxL)
PVCG3341_09120(lpxL)
MMKMU9_1856 MU9_2673
ANSArsFIN_45070(lpxP_2) ArsFIN_46420(lpxP_3)
MWIMNY66_09615(lpxL)
EICNT01EI_3298
ETRETAE_2920
ETDETAF_2652
ETEETEE_1146
ETCETAC_14060
EDWQY76_05725
EDLAAZ33_15520(lpxL)
EHOA9798_02615
HAVAT03_16890
HPARAL518_09765
OPODSM2777_08335
AGZM0C34_03670(lpxL)
SADEGFK82_00143(lpxP)
AKATKWG_01530
AMIMMIM_c02530
 » show all
Reference
1  [PMID:10092655]
  Authors
Carty SM, Sreekumar KR, Raetz CR
  Title
Effect of cold shock on lipid A biosynthesis in Escherichia coli. Induction At 12 degrees C of an acyltransferase specific for palmitoleoyl-acyl carrier protein.
  Journal
J Biol Chem 274:9677-85 (1999)
DOI:10.1074/jbc.274.14.9677
  Sequence
[eco:b2378]
Reference
2  [PMID:11830594]
  Authors
Vorachek-Warren MK, Carty SM, Lin S, Cotter RJ, Raetz CR
  Title
An Escherichia coli mutant lacking the cold shock-induced palmitoleoyltransferase of lipid A biosynthesis: absence of unsaturated acyl chains and antibiotic hypersensitivity at 12 degrees C.
  Journal
J Biol Chem 277:14186-93 (2002)
DOI:10.1074/jbc.M200408200
  Sequence
[eco:b2378]
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.242
IUBMB Enzyme Nomenclature: 2.3.1.242
ExPASy - ENZYME nomenclature database: 2.3.1.242
BRENDA, the Enzyme Database: 2.3.1.242
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