KEGG   ENZYME: 2.3.3.7
Entry
EC 2.3.3.7                  Enzyme                                 
Name
3-ethylmalate synthase;
2-ethyl-3-hydroxybutanedioate synthase;
3-ethylmalate glyoxylate-lyase (CoA-butanoylating)
Class
Transferases;
Acyltransferases;
Acyl groups converted into alkyl groups on transfer
Sysname
butanoyl-CoA:glyoxylate C-butanoyltransferase (thioester-hydrolysing, 1-carboxypropyl-forming)
Reaction(IUBMB)
butanoyl-CoA + H2O + glyoxylate = 3-ethylmalate + CoA [RN:R01180]
Reaction(KEGG)
R01180
Substrate
butanoyl-CoA [CPD:C00136];
H2O [CPD:C00001];
glyoxylate [CPD:C00048]
Product
3-ethylmalate [CPD:C01989];
CoA [CPD:C00010]
History
EC 2.3.3.7 created 1965 as EC 4.1.3.10, modified 1983, transferred 2002 to EC 2.3.3.10
Pathway
ec00630  Glyoxylate and dicarboxylate metabolism
Reference
1  [PMID:13314642]
  Authors
RAMASARMA T, GIRI KV.
  Title
Phosphoglucose isomerase of green gram (Phaseolus radiatus).
  Journal
Arch Biochem Biophys 62:91-6 (1956)
DOI:10.1016/0003-9861(56)90091-1
Other DBs
ExplorEnz - The Enzyme Database: 2.3.3.7
IUBMB Enzyme Nomenclature: 2.3.3.7
ExPASy - ENZYME nomenclature database: 2.3.3.7
BRENDA, the Enzyme Database: 2.3.3.7
CAS: 9024-01-5
LinkDB

KEGG   REACTION: R01180
Entry
R01180                      Reaction                               
Name
butanoyl-CoA:glyoxylate C-butanoyltransferase (thioester-hydrolysing, 1-carboxypropyl-forming);
3-ethylmalate glyoxylate-lyase (CoA-butanoylating)
Definition
3-Ethylmalate + CoA <=> Butanoyl-CoA + H2O + Glyoxylate
Equation
C01989 + C00010 <=> C00136 + C00001 + C00048
Reaction class
RC00004  C00010_C00136
RC00311  C00048_C01989
Enzyme
2.3.3.7
Pathway
rn00630  Glyoxylate and dicarboxylate metabolism
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.7
     R01180  3-Ethylmalate + CoA <=> Butanoyl-CoA + H2O + Glyoxylate
Other DBs
RHEA: 10503
LinkDB

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