| Entry |
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| Name |
8-demethyltetracenomycin C L-rhamnosyltransferase;
elmGT
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| Class |
Transferases;
Glycosyltransferases;
Hexosyltransferases
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| Sysname |
dTDP-beta-L-rhamnose:8-demethyltetracenomycin C 3-alpha-L-rhamnosyltransferase
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| Reaction(IUBMB) |
dTDP-beta-L-rhamnose + 8-demethyltetracenomycin C = dTDP + 8-demethyl-8-alpha-L-rhamnosyltetracenomycin C [RN: R10955]
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| Reaction(KEGG) |
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| Substrate |
dTDP-beta-L-rhamnose [CPD: C03319];
8-demethyltetracenomycin C [CPD: C12379]
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| Product |
dTDP [CPD: C00363];
8-demethyl-8-alpha-L-rhamnosyltetracenomycin C [CPD: C20974]
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| Comment |
Isolated from Streptomyces olivaceus Tu2353. Involved in elloramycin biosynthesis. In vitro it can also utilize other 6-deoxy D- or L-hexoses.
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| History |
EC 2.4.1.331 created 2014
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| Pathway |
| ec01057 | Biosynthesis of type II polyketide products |
| ec01110 | Biosynthesis of secondary metabolites |
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| Orthology |
| K19566 | 8-demethyltetracenomycin C L-rhamnosyltransferase |
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| Reference |
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| Authors |
Blanco G, Patallo EP, Brana AF, Trefzer A, Bechthold A, Rohr J, Mendez C, Salas JA |
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| Title |
Identification of a sugar flexible glycosyltransferase from Streptomyces olivaceus, the producer of the antitumor polyketide elloramycin. |
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| Journal |
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| Sequence |
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| Other DBs |
| ExPASy - ENZYME nomenclature database: | 2.4.1.331 |
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| LinkDB |
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