KEGG   ENZYME: 2.4.1.399
Entry
EC 2.4.1.399                Enzyme                                 
Name
phenyllactate glucosyltransferase;
UGT1
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
Sysname
UDP-alpha-D-glucose:(R)-3-(phenyl)lactate O-beta-D-glucosyltransferase
Reaction(IUBMB)
UDP-alpha-D-glucose + (R)-3-(phenyl)lactate = UDP + (R)-(phenyl)lactyl-beta-D-glucose [RN:R12916]
Reaction(KEGG)
R12916
Substrate
UDP-alpha-D-glucose [CPD:C00029];
(R)-3-(phenyl)lactate [CPD:C05607]
Product
UDP [CPD:C00015];
(R)-(phenyl)lactyl-beta-D-glucose
Comment
Isolated from the plant Atropa belladonna (deadly nightshade). Involved in the biosynthesis of littorine
History
EC 2.4.1.399 created 2025
Pathway
ec00960  Tropane, piperidine and pyridine alkaloid biosynthesis
ec01110  Biosynthesis of secondary metabolites
Orthology
K25582  phenyllactate glucosyltransferase
Genes
SLY101250429
SPEN107028035
SOT102603881
SSTN125842354
SDUL129888968
LBB132609333
Reference
1  [PMID:31705812]
  Authors
Qiu F, Zeng J, Wang J, Huang JP, Zhou W, Yang C, Lan X, Chen M, Huang SX, Kai G, Liao Z.
  Title
Functional genomics analysis reveals two novel genes required for littorine biosynthesis.
  Journal
New Phytol 225:1906-1914 (2020)
DOI:10.1111/nph.16317
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.399
IUBMB Enzyme Nomenclature: 2.4.1.399
ExPASy - ENZYME nomenclature database: 2.4.1.399
BRENDA, the Enzyme Database: 2.4.1.399
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