Entry
Name
5,10-dihydrophenazine-1-carboxylate 9-dimethylallyltransferase;
PpzP;
dihydrophenazine-1-carboxylate dimethylallyltransferase;
5,10-dihydrophenazine 1-carboxylate dimethylallyltransferase;
dimethylallyl diphosphate:5,10-dihydrophenazine-1-carboxylate 9-dimethylallyltransferase
Class
Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
BRITE hierarchy
Sysname
prenyl-diphosphate:5,10-dihydrophenazine-1-carboxylate 9-prenyltransferase
Reaction(IUBMB)
prenyl diphosphate + 5,10-dihydrophenazine-1-carboxylate = diphosphate + 9-prenyl-5,10-dihydrophenazine-1-carboxylate [RN:
R10966 ]
Reaction(KEGG)
Substrate
prenyl diphosphate [CPD:
C00235 ];
5,10-dihydrophenazine-1-carboxylate [CPD:
C20981 ]
Product
diphosphate [CPD:
C00013 ];
9-prenyl-5,10-dihydrophenazine-1-carboxylate [CPD:
C20982 ]
Comment
The enzyme is involved in the biosynthesis of prenylated phenazines by the bacterium Streptomyces anulatus. It is specific for both prenyl diphosphate and 5,10-dihydrophenazine-1-carboxylate.
History
EC 2.5.1.121 created 2014
Pathway
ec01110 Biosynthesis of secondary metabolites
Orthology
K21338 5,10-dihydrophenazine-1-carboxylate 9-dimethylallyltransferase
Reference
Authors
Saleh O, Gust B, Boll B, Fiedler HP, Heide L
Title
Aromatic prenylation in phenazine biosynthesis: dihydrophenazine-1-carboxylate dimethylallyltransferase from Streptomyces anulatus.
Journal
Sequence
Other DBs
ExPASy - ENZYME nomenclature database: 2.5.1.121
LinkDB
All DBs