KEGG   ENZYME: 2.5.1.89
Entry
EC 2.5.1.89                 Enzyme                                 
Name
tritrans,polycis-undecaprenyl diphosphate synthase [geranylgeranyl-diphosphate specific]
Class
Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
Sysname
geranylgeranyl-diphosphate:isopentenyl-diphosphate cistransferase (adding 7 isopentenyl units)
Reaction(IUBMB)
geranylgeranyl diphosphate + 7 isopentenyl diphosphate = 7 diphosphate + tritrans,heptacis-undecaprenyl diphosphate [RN:R09730]
Reaction(KEGG)
R09730
Substrate
geranylgeranyl diphosphate [CPD:C00353];
isopentenyl diphosphate [CPD:C00129]
Product
diphosphate [CPD:C00013];
tritrans,heptacis-undecaprenyl diphosphate [CPD:C19852]
Comment
This enzyme is involved in the biosynthesis of the glycosyl carrier lipid in some archaebacteria. Unlike EC 2.5.1.31, its counterpart in most bacteria, it prefers geranylgeranyl diphosphate to farnesyl diphosphate as the allylic substrate, resulting in production of a tritrans,polycis variant of undecaprenyl diphosphate [1].
History
EC 2.5.1.89 created 2010, modified 2011
Pathway
ec00900  Terpenoid backbone biosynthesis
Orthology
K15888  tritrans,polycis-undecaprenyl-diphosphate synthase [geranylgeranyl-diphosphate specific]
Genes
MRFMJO55_07290
MJAMJ_1372
MFEMefer_0013
MVUMetvu_0730
MFSMFS40622_0557
MIFMetin_0747
MJHJH146_0409
MESGMLAUSG7_0959(uppS)
MESAMLASG1_0294(uppS)
MIGMetig_0007
MMPMMP1345
MMQMmarC5_0233
MMXMmarC6_1328
MMZMmarC7_0590
MMDGYY_07550
MMAKMMKA1_15680(uppS)
MMAOMMOS7_14490(uppS)
MMADMMJJ_14940
MAEMaeo_1136
MVNMevan_0656
MVOMvol_0149
MOKMetok_0698
METFCFE53_05195(uppS)
MTHMTH_232
MMGMTBMA_c06810(uppS)
METCMTCT_0194
MWOMWSIV6_0644(uppS)
METEtca_00212
METZMETMT2_0676
METKFVF72_01145(uppS)
MTHMFZP57_03065(uppS)
METJFZP68_08100(uppS)
MTEEMTTB_08750
MSTMsp_1182(uppS)
METBAW729_09855
MRUmru_1005(uppS)
MSIMsm_0096
MEBAbm4_0676(uppS)
MMILsm9_0974(uppS)
MEYETL18_05495
MOLYLM1_0546
MAROMarbSA_04520
MELMetbo_2128
MEWMSWAN_0483
METHMBMB1_0608(uppS)
MFCBRM9_1627(uppS)
MFIDSM1535_2322(uppS)
MCUBMCBB_0494(uppS)
MSUBBK009_01135
METNBK008_08825
METTCIT01_09500(uppS)
METOCIT02_03890(uppS)
MEMEHYG87_09880(uppS)
MFVMfer_0595
MKAMK0767(uppS)
AFUAF_1219
AFGAFULGI_00007890 AFULGI_00013180
APOArcpr_0260 Arcpr_0491
AVEArcve_0125
ASTAsulf_00506 Asulf_01284
FPLFerp_1985
GACGACE_0233
GAHGAH_00064
PFUPF1599
PFIPFC_07225
PHOPH1590(PH1590)
PABPAB0394(hypoth)
PYNPNA2_0175
PYAPYCH_04910
PYSPy04_1477
PYCTQ32_08915
TKOTK1173
TONTON_0373
TGATGAM_0719(uppS)
TSITSIB_1513
TBATERMP_00685
THEGQS_03365
THATAM4_934
THMCL1_0304
TLTOCC_03007
THSTES1_0768
TNUBD01_0338
TEUTEU_07395
TGYX802_06815
THVADU37_CDS16370
TCHCHITON_1826
TPEPA0127_09070
TPIEA7C91_07885
TGGA3K92_05410
TCEA3L02_09525
TBSA3L01_02570
THHCDI07_02520(uppS)
TSLA3L11_06495
TTDA3L14_04035
TPRFA3L09_07815
TRLA3L10_04015
TPAFA3L08_05560
THYA3L12_06160
TICFH039_04835(uppS)
TCQTIRI35C_0737(uppS)
THEMFPV09_04325(uppS)
PPACPAP_02925
MBAMbar_A0263
MBYMSBRM_2692
MBWMSBRW_0733
MBARMSBR2_2648
MBAKMSBR3_2777
MACMA_3723(uppS)
MMAMM_0618
MMAZMmTuc01_0629
MMJMSMAS_0691
MMACMSMAC_0692
MVCMSVAZ_0672
MEKMSKOL_0650
MLSMSLAZ_2243
METMMSMTP_0756
MEFMSWH1_0870
MEQMSWHS_0929
MSJMSSAC_3535
MSZMSSIH_3076
MSWMSSIT_3134
MTHRMSTHT_2395
MTHEMSTHC_0884
MHORMSHOH_0806
MFZAOB57_003440(uppS)
MBUMbur_0041
MMETMCMEM_0626
MELOJ7W08_01190(uppS)
MMHMmah_1238
MHAZBHR79_07355
MEVMetev_0825 Metev_2270
MZHMzhil_1185
MPYMpsy_1109
MZIHWN40_03045(uppS)
MHZMetho_1987
MTPMthe_0589
MCJMCON_0296(uppS)
MHIMhar_2350
MHUMhun_0785
MRTJKHC33_09690(uppS)
MLAMlab_0118
MEMMemar_1788
MBGBN140_0601(uppS)
MEMAMMAB1_0780(uppS)
MCHKMchiMG62_20500
MPIMpet_0736
MBNMboo_2063
MFOMetfor_0792
MPLMpal_0107
MPDMCP_1817(uppS)
MEZMtc_1306(uppS-2)
RCIRRC441(uppS-2)
HALVNG_1779C
HSLOE_3503F(uppS1)
HDLHALDL1_13885
HHBHhub_3075(uppS1)
HAGSJT689_08515(uppS)
HABOJRZ79_06925(uppS)
HNOLT974_12305(uppS)
HLULT972_02610(uppS)
HANRLJ422_07170(uppS)
HJEHacjB3_06135
HALHHTSR_0407
HHSRHSR6_0392(uppS2)
HSUHLASF_1850(uppS1)
HSFHLASA_1836(uppS1)
SALRFQU85_06950(uppS)
HALREFA46_001210(uppS)
HARAAArcS_0442(uppS)
HAADMW046_02285(uppS)
HALXM0R89_02070(uppS)
HMArrnAC1716(uppS)
HHIHAH_2250(uppS1)
HHNHISP_11460
HABSG26_03830
HTABVU17_10985
HALJG9465_16135(uppS)
HSINKDQ40_02130(uppS)
NPHNP_4550A(uppS1)
NMONmlp_2341(uppS1)
NHOHWV23_03155(uppS)
NSALHWV07_17065(uppS)
HUTHuta_2829
HTIHTIA_2734
HALAHrd1104_05035(uppS)
HMUHmuk_1548
HALZE5139_10865(uppS)
HALLLC1Hm_0765(uppS)
HAZPGBQ70_10860(uppS)
HALIBV210_13510
HSNDV733_13415(uppS)
HDSHSR122_1525(uppS)
HRRHZS55_13135(uppS)
HPELHZS54_17080(uppS)
HLTI7X12_00640(uppS)
HARCHARCEL1_06025(uppS)
HDOMUK72_12540(uppS)
HWAHQ_3332A(uppS2)
HWCHqrw_3861(uppS2)
HVOHVO_2315(uppS1)
HMEHFX_2325(uppS)
HGIABY42_11520
HALEG3A49_14790(uppS)
HBOHbor_07310
HAQDU484_16985(uppS)
HAJDU500_00030(uppS)
HAERDU502_15195(uppS)
HRAEI982_15070(uppS)
HLMDV707_01865(uppS)
HALMFCF25_03620(uppS)
HLAHlac_2063
HALPDOS48_09765(uppS)
HALBEKH57_14675(uppS)
HEZZEO776_10170(uppS)
HALQHrr1229_012105(uppS)
HSSJ7656_05270(uppS)
HSAIHPS36_03735(uppS) HPS36_10485(uppS)
HAZZKI388_09475(uppS)
SRUBC2R22_16735(uppS)
HAEhalTADL_0759 halTADL_1546
HALNB4589_014625(uppS)
HALGHUG10_08895(uppS)
HALUHUG12_07165(uppS)
HMPK6T50_06435(uppS)
HREK6T36_06210(uppS)
HRMK6T25_09575(uppS)
HACBHbl1158_13150(uppS)
HDFAArcSl_1515
HAHHalar_2577
HTUHtur_3250
HDABB347_00350
HJTDVR14_12120(uppS)
HSALJMJ58_12205(uppS)
HLOJ0X27_13255(uppS)
HAKZJ0X25_04460(uppS)
NMGNmag_1224(uppS1)
HXAHalxa_2121
NATNJ7G_2495
NPENatpe_0579
NVRFEJ81_03230(uppS)
NPLFGF80_07730(uppS)
NAYHYG81_07640(uppS)
HALYHYG82_10385(uppS)
NGENatgr_3192
HRUHalru_2195
NOUNatoc_2038
SALIL593_09975
SAIMK0C01_03025(uppS)
HLRHALLA_17025
HLCCHINAEXTREME08125
NAJB1756_11845
NAGAArcMg_3021
NANAArc1_0682
NBGDV706_03890(uppS)
NASGCU68_09075(uppS)
MEAMMU439_01005(uppS)
TACTa0546
TVOTVG0591988(TVG0591988)
PTOPTO1378
FACFACI_IFERC01G1594
FAIFAD_0573
CDIVCPM_0361
TARTALC_00206
MAXMMALV_01930
MERMMINT_01960
MEARMpt1_c12690(uppS)
MARCAR505_1636
ABIAboo_0417
ACFAciM339_0631
ACJACAM_0874(uppS)
SMRSmar_1245
SHCShell_1211
IHOIgni_0586
IISEYM_01550
DKADKAM_0927
DFDDesfe_1048
DMUDesmu_0134
TAGTagg_0145
IAGIgag_0013
THGTCELL_0064
HBUHbut_1087
PFMPyrfu_1960
PDLPyrde_0981
STOSTK_01890(uppS)
SOHD1869_00415(uppS)
SSOSSO0163
SOLSsol_1140
SSOASULA_1176(uppS)
SSOLSULB_1177(uppS)
SSOFSULC_1175(uppS)
SSHIJ5U23_00102
SCASSACC_00750
SAISaci_0757
SACNSacN8_03680
SACRSacRon12I_03665
SACSSUSAZ_03395
SISLS215_2142
SIAM1425_1977
SIMM1627_2055
SIDM164_1983
SIYYG5714_2100
SINYN1551_0818
SIILD85_2238
SIHSiH_1921
SIRSiRe_1848
SICSiL_1830
SULABFU36_05125
SULEGFS03_10830(uppS)
SULLEWF20_01855(uppS)
MSEMsed_0171
MCNMcup_1902
MHKDFR87_05955(uppS)
MPRUDFR88_05785(uppS)
MTENGWK48_06235(uppS)
MJNMjAS7_0754
AHOAhos_0890
AMANB6F84_08300
ABRIDFR85_06545(uppS)
ASULDFR86_07315(uppS)
AAMBD1866_12345(uppS)
ACIHHS5_22650
SACDHS1genome_0851
SAZOD1868_01560(uppS)
CSTYKN1_18100
STEPIC006_1909
SAHSHS7_19990
PISPisl_0348
PCLPcal_1157
PASPars_1319
PYRP186_1582
POGPogu_0896
TNETneu_1777
PYWPYWP30_01898
CMACmaq_0786
TTNTTX_0656(uppS)
TUZTUZN_0298
VDIVdis_0938
VMOVMUT_1786
TPETpen_0762
THBN186_05330
TCBTCARB_0131
THFMA03_05695
THELIG193_03675(uppS)
ASCASAC_1265
ACIASE86_07500
CLGCalag_0868
FFOFFONT_1224
NMRNmar_1416
NIRNSED_07775
NKRNKOR_07805
NIDNPIRD3C_2077(uppS)
NINNADRNF5_0463(uppS)
NIWNisw_06890(uppS)
NCLC5F47_07515(uppS)
NOXC5F49_07395(uppS)
NUEC5F50_10710(uppS)
NIPNsoK4_01175(uppS)
NCTNMSP_0329(uppS)
NICDSQ20_08340(uppS)
CSYCENSYa_1470
NGANgar_c35510(uppS)
NVNNVIE_018850
NEVNTE_00400
TAANMY3_03347
NFNNFRAN_0752(uppS)
NCVNCAV_0511(uppS)
CSUCSUB_C0295
NBVT478_0360(uppS)
TAHSU86_008615
NIUDSQ19_07980(uppS)
NDVNDEV_1710(uppS)
CCAINAS2_0133
KCRKcr_0245
BARCAOA65_0926(uppS)
BARBAOA66_0322(uppS)
NAANps_02790
MARHMia14_0585
FLTSv326_1286
MIYMicr_00783(uppS_2)
LOKILokiarch_02280(uppS_1) Lokiarch_37300(uppS_2)
PSYTDSAG12_01206(uppS)
AGWQT03_C0001G0549 QT03_C0001G0683(uppS) QT03_C0001G0830
ARGQT11_C0001G0984
 » show all
Reference
1  [PMID:11114943]
  Authors
Hemmi H, Yamashita S, Shimoyama T, Nakayama T, Nishino T
  Title
Cloning, expression, and characterization of cis-polyprenyl diphosphate synthase from the thermoacidophilic archaeon Sulfolobus acidocaldarius.
  Journal
J Bacteriol 183:401-4 (2001)
DOI:10.1128/JB.183.1.401-404.2001
  Sequence
[sai:Saci_0757]
Other DBs
ExplorEnz - The Enzyme Database: 2.5.1.89
IUBMB Enzyme Nomenclature: 2.5.1.89
ExPASy - ENZYME nomenclature database: 2.5.1.89
BRENDA, the Enzyme Database: 2.5.1.89
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