KDG kinase (ambiguous);
2-keto-3-deoxy-D-gluconate kinase (ambiguous)
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
(1) ATP + 2-dehydro-3-deoxy-D-gluconate = ADP + 2-dehydro-3-deoxy-6-phospho-D-gluconate [RN:
(2) ATP + 2-dehydro-3-deoxy-D-galactonate = ADP + 2-dehydro-3-deoxy-6-phospho-D-galactonate [RN:
The enzyme from the archaeon Sulfolobus solfataricus is involved in glucose and galactose catabolism via the branched variant of the Entner-Doudoroff pathway. It phosphorylates 2-dehydro-3-deoxy-D-gluconate and 2-dehydro-3-deoxy-D-galactonate with similar catalytic efficiency. cf. EC
, 2-dehydro-3-deoxygluconokinase and EC
EC 220.127.116.11 created 2013
K18126 2-dehydro-3-deoxygluconokinase / 2-dehydro-3-deoxygalactonokinase
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Lamble HJ, Theodossis A, Milburn CC, Taylor GL, Bull SD, Hough DW, Danson MJ
Promiscuity in the part-phosphorylative Entner-Doudoroff pathway of the archaeon Sulfolobus solfataricus.
Potter JA, Kerou M, Lamble HJ, Bull SD, Hough DW, Danson MJ, Taylor GL
The structure of Sulfolobus solfataricus 2-keto-3-deoxygluconate kinase.
Kim S, Lee SB
Characterization of Sulfolobus solfataricus 2-keto-3-deoxy-D-gluconate kinase in the modified Entner-Doudoroff pathway.
ExPASy - ENZYME nomenclature database: 18.104.22.168
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