KEGG ENZYME: 2.7.1.213

ENZYME: 2.7.1.213

Entry

EC 2.7.1.213                Enzyme

Name

cytidine kinase

Class

Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor

Sysname

ATP:cytidine 5'-phosphotransferase

Reaction(IUBMB)

ATP + cytidine = ADP + CMP [RN:R00513]

Reaction(KEGG)

R00513;
(other) R00964 R01666

Substrate

ATP [CPD:C00002];
cytidine [CPD:C00475]

Product

ADP [CPD:C00008];
CMP [CPD:C00055]

Comment

The enzyme, characterized from the archaeon Thermococcus kodakarensis, participates in a pathway for nucleoside degradation. The enzyme can also act on deoxycytidine and uridine, but unlike EC 2.7.1.48, uridine kinase, it is most active with cytidine.

History

EC 2.7.1.213 created 2016

Pathway

ec00240

Pyrimidine metabolism

ec01100

Metabolic pathways

Orthology

K21057

cytidine kinase

K22026

nucleoside kinase

Genes

NOH:	G5V57_09000

CBT:

CLH_3246

CLB:	Clo1100_3013

CCL:	Clocl_2480

CCE:

Ccel_1080

RPAY:

P0092_17380

CCEL:

CCDG5_0763

ACOL:

K5I23_12490

PROM:

QO263_16190

CCOM:

I6K69_07805

KIB:	RBB56_06565

LBW:	C3V36_01730

VGU:	HYG85_10135

HALS:

D7D81_02150

OLS:

Olsu_1249

STRL:

HEP84_35745

TNR:	Thena_0742

TACI:

TDSAC_0711

TPAV:

HRQ91_00140

TAM:	Theam_1686

DTE:	Dester_0039

MJA:

MJ_0406

MFE:	Mefer_1313

MVU:	Metvu_0829

MFS:	MFS40622_1675

MIF:	Metin_0950

MJH:	JH146_1321

MESG:

MLAUSG7_0701

MESA:

MLASG1_0143

MIG:	Metig_0129

MMP:

MMP0418

MMQ:	MmarC5_1220

MMX:	MmarC6_0492

MMZ:	MmarC7_1416

MMD:

GYY_02160

MMAK:

MMKA1_04370(pfkB)

MMAO:

MMOS7_04330(pfkB)

MMAD:

MMJJ_06190(adoK)

MAE:

Maeo_1201

MVN:	Mevan_1406

MVO:

Mvol_1641

MOK:	Metok_0835

METF:

CFE53_03915

MTH:

MTH_1544

MMG:	MTBMA_c01300

MWO:	MWSIV6_0084(rbsK)

MTEE:

MTTB_15630

METC:

MTCT_1409

METE:

tca_01493(adoK)

METZ:

METMT2_0044

METK:

FVF72_03900

MTHM:

FZP57_00360

METJ:

FZP68_05355

MST:

Msp_0252

METB:

AW729_05925

MEIS:

PXD04_05040

MRU:

mru_0246

MSI:

Msm_1389

MEB:

Abm4_0153

MMIL:

sm9_2189

MEYE:

TL18_00860

MOL:

YLM1_0015

MARO:

MarbSA_13460

METV:

K4897_04365

MEL:	Metbo_2524

MEW:	MSWAN_0107

METH:

MBMB1_0093

MFC:

BRM9_0158

MFI:	DSM1535_1480

MCUB:

MCBB_0117

MSUB:

BK009_10315

METN:

BK008_05935

METT:

CIT01_06160

METO:

CIT02_06550

MEME:

HYG87_07025

MFEG:

GCM10025860_08940

MEER:

NKF70_07250

MFV:

Mfer_0189

PYC:	TQ32_02245

TKO:

TK1843

TON:

TON_1686

TGA:

TGAM_0187

TSI:

TSIB_1949

TBA:	TERMP_01910

THE:

GQS_06905

THA:

TAM4_1366

THM:

CL1_1013

TLT:

OCC_10494

THS:

TES1_1867

TNU:

BD01_1774

TEU:

TEU_02660

TGY:	X802_04890

TPEP:

A0127_05975

TPIE:

A7C91_03685

TGG:	A3K92_08745

TCE:	A3L02_07180

TBS:	A3L01_09300

THH:	CDI07_09240

TSL:	A3L11_02800

TTD:	A3L14_00350

TPRF:

A3L09_01070

TRL:	A3L10_08755

TPAF:

A3L08_02230

THY:	A3L12_00155

TIC:	FH039_00935

TCQ:	TIRI35C_2199

THEM:

FPV09_09135

THEI:

K1720_02480

PPAC:

PAP_03105

MBA:	Mbar_A2903

MBY:	MSBRM_1434

MBW:	MSBRW_1835

MBAR:

MSBR2_0971

MBAK:

MSBR3_0268

MAC:

MA_1373

MMA:

MM_2358

MMAZ:

MmTuc01_2409

MMJ:	MSMAS_2341

MMAC:

MSMAC_2104

MVC:	MSVAZ_1777

MEK:	MSKOL_1753

MLS:	MSLAZ_0958

METM:

MSMTP_2169

MEF:	MSWH1_2302

MEQ:	MSWHS_2773

MSJ:	MSSAC_1381

MSZ:	MSSIH_1577

MSW:	MSSIT_1669

MTHR:

MSTHT_0846

MTHE:

MSTHC_2425

MHOR:

MSHOH_2963

MFZ:	AOB57_012265

MBU:

Mbur_0967

MMET:

MCMEM_1470

MELO:

J7W08_06110

MMH:

Mmah_0649

MHAZ:

BHR79_00120

MPOT:

BKM01_08295

MEV:	Metev_1413

MZH:	Mzhil_0761

MPY:

Mpsy_3162

MZI:	HWN40_07890

MMAV:

RE476_01890

MSEB:

RE474_11660

MHZ:	Metho_1694

MEHF:

MmiHf6_02950(adoK)

MEES:

MmiEs2_05980(adoK)

MHU:

Mhun_0077

MRTJ:

KHC33_04560

MLA:

Mlab_0932

MEM:	Memar_0859

MBG:	BN140_0912(pfkB)

MEMA:

MMAB1_1189

MCHK:

MchiMG62_09930

MSUM:

OH143_11010

MRC:	R6Y96_04625

MPI:

Mpet_2014

MEND:

L6E24_10560

MEFW:

F1737_02465

MAQE:

RJ40_11770

MFK:	E2N92_12105

MOU:	OU421_02870

MESB:

L1S32_06410

MANQ:

L1994_07055

MBN:

Mboo_1658

MFO:	Metfor_2415

MPL:

Mpal_1085

MEAM:

MU439_05570

MEAE:

QEN48_04590

TAC:

Ta0880

TVO:	TVG1031550(TVG1031550)

PTO:

PTO1237

FAC:	FACI_IFERC01G1340

FAI:

FAD_0353

CDIV:

CPM_1288

TAR:	TALC_00049

MAX:	MMALV_00600

MER:	MMINT_02620

MEAR:

Mpt1_c11870

MEUZ:

KRP56_00565

MARC:

AR505_1785

ABI:

Aboo_0480

ACF:	AciM339_0562

FLT:	Sv326_1301

LOKI:

Lokiarch_18030

» show all

Reference

1 [PMID:25822915]

Authors

Aono R, Sato T, Imanaka T, Atomi H

Title

A pentose bisphosphate pathway for nucleoside degradation in Archaea.

Journal

Nat Chem Biol 11:355-60 (2015)
DOI:10.1038/nchembio.1786

Sequence

[tko:TK1843]

Other DBs

ExplorEnz - The Enzyme Database:

2.7.1.213

IUBMB Enzyme Nomenclature:

2.7.1.213

ExPASy - ENZYME nomenclature database:

2.7.1.213

BRENDA, the Enzyme Database:

2.7.1.213

LinkDB

DBGET integrated database retrieval system