KEGG ENZYME: 2.7.1.216

ENZYME: 2.7.1.216

Entry

EC 2.7.1.216                Enzyme

Name

farnesol kinase;
FOLK (gene name)

Class

Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor

Sysname

CTP:(2E,6E)-farnesol phosphotransferase

Reaction(IUBMB)

CTP + (2E,6E)-farnesol = CDP + (2E,6E)-farnesyl phosphate [RN:R09849]

Reaction(KEGG)

R09849

Substrate

CTP [CPD:C00063];
(2E,6E)-farnesol [CPD:C01126]

Product

CDP [CPD:C00112];
(2E,6E)-farnesyl phosphate [CPD:C20121]

Comment

The enzyme, found in plants and animals, can also use other nucleotide triphosphates as phosphate donor, albeit less efficiently. The plant enzyme can also use geraniol and geranylgeraniol as substrates with lower activity, but not farnesyl phosphate (cf. EC 2.7.4.32, farnesyl phosphate kinase) [2].

History

EC 2.7.1.216 created 2017

Pathway

ec00900

Terpenoid backbone biosynthesis

ec01110

Biosynthesis of secondary metabolites

Orthology

K15892

farnesol kinase

Genes

ATH:	AT5G58560(FOLK)

ALY:

9302348

CRB:	17875624 17886534

CSAT:

104698976 104711386 104726429 104735756 104761955 104780712

EUS:	EUTSA_v10014180mg

BRP:	103845287 103856674 103856907

BNA:	106376298 106385189 106385190 106420546 106435924 106435934

BOE:	106313208 106334947 106334948

RSZ:	108823783 108848087 108848088 130502590 130502591

THJ:	104799389 104799865

CPAP:

110823862

CIT:

102607196

CIC:	CICLE_v10028969mg

PVY:

116130238

MINC:

123209613

TCC:

18590992

GRA:	105783806 105789011

GHI:	107927038 107936061 107957660 107963843

GAB:	108480963 108484512

HSYR:

120148215 120161781 120185589

DZI:	111286046 111301486

EGR:	104418390 104418392

GMX:

100793696

GSJ:

114397687

PVU:	PHAVU_006G071000g

VRA:

106752668

VAR:

108341074

VUN:

114187077

VUM:

124836808

CCAJ:

109814795

APRC:

113850147

MTR:	25490962 25491456 25491458

TPRA:

123915118 123916899

CAM:	101508675 101508996

PSAT:

127084524

VVO:	131628570 131628765

LJA:

130723834

ADU:

107473329

AIP:

107648557

AHF:	112719976 112792546

LANG:

109352111

PCIN:

129299174 129318535

QSA:	O6P43_014078 O6P43_020373

FVE:

101312326

RCN:

112166567

PPER:

18773060

PMUM:

103321386

PAVI:

110758741

PDUL:

117632803

MDM:

103419955

MSYL:

126591118 126615528

PXB:

103958984

ZJU:

107411489

MNT:

21394929

CSAV:

115719607

CSV:

101220953

CMO:

103497053

BHJ:

120082414

MCHA:

111018992

CMAX:

111469454 111493313

CMOS:

111452098 111464846

CPEP:

111782599 111787425

RCU:

8272401

MEAN:

126670520

JCU:

105639148

HBR:

110634309

MESC:

110605789

POP:	18109105 7487814

PEU:	105110415 105126052

PALZ:

118027566 118032874 118055597

JRE:

108996986

CILL:

122292837

CAVE:

132163768 132163770 132164031

QSU:

112003510

QLO:

115989892

TWL:

120003144

VVI:	100243279 100265588

VRI:	117915594 117916906

SLY:

101252619

SPEN:

107029162

SOT:

102606110

SSTN:

125871255

SDUL:

129882526

CANN:

107851334

LBB:

132631006

NTA:	107798184 107802957 107825879

NSY:

104237922

NTO:	104088379 104098382

NAU:

109214544

INI:

109164267

ITR:

116015191

SIND:

105177430 105177431

OEU:	111367046 111400761 111402577

EGT:	105964397 105964400

SSPL:

121756461 121760315 121762773 121763215 121764574 121764706 121793031

SMIL:

131013965 131016051 131016052

SHIS:

125185333 125198287 125198711 125202649 125205661 125223034

APAN:

127244510 127258155

HAN:	110884628 110936154 110939702

ECAD:

122592675 122592836 122608516

LSV:	111881754 111881777 111900633

CCAV:

112518182

DCR:	108215602 108223537

CSIN:

114258091

RVL:

131314289

AEW:

130770860

BVG:

104903117

SOE:	110803557 110803567

CQI:	110681594 110711948

ATRI:

130805491

MOF:	131147578 131147800

NNU:

104602694

MING:

122089913

TSS:

122638290

PSOM:

113284213 113355432

OSA:	4327435 4349551 4351259

OBR:	102715340 102717944

OGL:	127753647 127757600 127760634

BDI:	100826738 100838535

ATS:	109769583 109780312 109780318

TDC:	119269473 119272646 119277476 119301004

TAES:

123044293 123057026 123062489 123062936 123065878 123071295 123076365 123079639 123106884 123115995 123124621

TUA:	125521241 125525062 125545199 125546997 125555917

LPER:

127300139 127300140 127344708

LRD:	124651481 124652894 124661576 124665063

SBI:	8055486 8079965 8085428

ZMA:

100191275

MFLO:

136459353 136481327 136481344 136504286 136508787

SITA:

101761907 101778737 101781291

SVS:	117857107 117864528 117866590

PVIR:

120643375 120674265 120685552 120694042 120696498 120708549

PHAI:

112878635 112886295 112893785 112902701

PDA:	103718108 103722776

EGU:

105036025

MUS:

103999851

ZOF:	122008528 122016333 122036007 122036023

DCT:

110098089

PEQ:	110018674 110026549

AOF:

109829993

MSIN:

131253393

NCOL:

116262082 116262083

ATR:

18437155

SMO:	SELMODRAFT_230719 SELMODRAFT_95672

PPP:	112279064 112294085

APRO:

F751_5656

SRE:	PTSG_03426

EHX:	EMIHUDRAFT_369009 EMIHUDRAFT_436338

» show all

Reference

1 [PMID:9606952]

Authors

Bentinger M, Grunler J, Peterson E, Swiezewska E, Dallner G

Title

Phosphorylation of farnesol in rat liver microsomes: properties of farnesol kinase and farnesyl phosphate kinase.

Journal

Arch Biochem Biophys 353:191-8 (1998)
DOI:10.1006/abbi.1998.0611

Reference

2 [PMID:21395888]

Authors

Fitzpatrick AH, Bhandari J, Crowell DN

Title

Farnesol kinase is involved in farnesol metabolism, ABA signaling and flower development in Arabidopsis.

Journal

Plant J 66:1078-88 (2011)
DOI:10.1111/j.1365-313X.2011.04572.x

Sequence

[ath:AT5G58560]

Other DBs

ExplorEnz - The Enzyme Database:

2.7.1.216

IUBMB Enzyme Nomenclature:

2.7.1.216

ExPASy - ENZYME nomenclature database:

2.7.1.216

BRENDA, the Enzyme Database:

2.7.1.216

LinkDB

DBGET integrated database retrieval system