KEGG   ENZYME: 2.7.11.12
Entry
EC 2.7.11.12                Enzyme                                 
Name
cGMP-dependent protein kinase;
3':5'-cyclic GMP-dependent protein kinase;
cGMP-dependent protein kinase Ibeta;
guanosine 3':5'-cyclic monophosphate-dependent protein kinase;
PKG;
PKG 1alpha;
PKG 1beta;
PKG II;
STK23
Class
Transferases;
Transferring phosphorus-containing groups;
Protein-serine/threonine kinases
Sysname
ATP:protein phosphotransferase (cGMP-dependent)
Reaction(IUBMB)
ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Reaction(KEGG)
R00162
Substrate
ATP [CPD:C00002];
protein [CPD:C00017]
Product
ADP [CPD:C00008];
phosphoprotein [CPD:C00562]
Comment
CGMP is required to activate this enzyme. The enzyme occurs as a dimer in higher eukaryotes. The C-terminal region of each polypeptide chain contains the catalytic domain that includes the ATP and protein substrate binding sites. This domain catalyses the phosphorylation by ATP to specific serine or threonine residues in protein substrates [3]. The enzyme also has two allosteric cGMP-binding sites (sites A and B). Binding of cGMP causes a conformational change that is associated with activation of the kinase [4].
History
EC 2.7.11.12 created 2005 (EC 2.7.1.37 part-incorporated 2005)
Orthology
K07376  cGMP-dependent protein kinase 1
K19477  cGMP-dependent protein kinase 2
Genes
HSA5592(PRKG1) 5593(PRKG2)
PTR461217(PRKG2) 744467(PRKG1)
PPS100975252(PRKG1) 100978260(PRKG2)
GGO101139285(PRKG2)
PON100437791(PRKG1) 100438589(PRKG2)
NLE100584834(PRKG2) 100597697(PRKG1)
MCC696308(PRKG2) 703356(PRKG1)
MCF102122483(PRKG1) 102142098(PRKG2)
CSAB103216192(PRKG1) 103235875(PRKG2)
CATY105576820(PRKG2) 105587190(PRKG1)
PANU101021599(PRKG2)
TGE112624826(PRKG2) 112631135(PRKG1)
RRO104654813(PRKG2) 104676729(PRKG1)
RBB108543451(PRKG2)
TFN117085403(PRKG2) 117085919(PRKG1)
PTEH111549391(PRKG2) 111551296(PRKG1)
CJC100384937(PRKG2) 100388016(PRKG1)
SBQ101033123(PRKG2) 101043597(PRKG1)
CSYR103272881(PRKG2) 103275000
MMUR105870362(PRKG1) 105880962(PRKG2)
LCAT123627373(PRKG2) 123650455(PRKG1)
OGA100941256(PRKG2) 100955814(PRKG1)
MMU19091(Prkg1) 19092(Prkg2)
MCAL110285294(Prkg1) 110294464(Prkg2)
MPAH110313055(Prkg1) 110330505(Prkg2)
RNO25523(Prkg2) 54286(Prkg1)
MCOC116067909(Prkg2) 116103727(Prkg1)
MUN110562188(Prkg2)
CGE100765312(Prkg2) 100768615(Prkg1)
MAUA101826743(Prkg1) 101827998(Prkg2)
PLEU114695723(Prkg2) 114710735(Prkg1)
MORG121453885(Prkg1) 121460822(Prkg2)
AAMP119811553(Prkg1) 119817224(Prkg2)
NGI103732508(Prkg1) 103735969(Prkg2)
HGL101697843(Prkg2) 101708361(Prkg1)
CPOC100724794(Prkg2) 100734084(Prkg1)
CCAN109702659(Prkg2)
DORD105986321(Prkg1) 105988515(Prkg2)
DSP122106688(Prkg2) 122115721(Prkg1)
NCAR124984630
OCU100008694(PRKG1) 100008781(PRKG2)
OPI101526065(PRKG1) 101534728(PRKG2)
TUP102489899(PRKG2)
CFA100855930(PRKG2) 609616(PRKG1)
VVP112919705(PRKG2) 112931969(PRKG1)
VLG121475369(PRKG1) 121493652(PRKG2)
AML100467892(PRKG2) 100481505(PRKG1)
UMR103661993(PRKG1) 103665352(PRKG2)
UAH113258870(PRKG1) 113263226(PRKG2)
UAR123787502(PRKG2) 123795560(PRKG1)
ELK111145213 111149130
LLV125085296 125093912
MPUF101673181(PRKG2) 101687177(PRKG1)
ORO101381093(PRKG2)
EJU114210308(PRKG1) 114224927(PRKG2)
ZCA113922106(PRKG1) 113924739(PRKG2)
MLX118010403(PRKG2) 118012977(PRKG1)
FCA101091618(PRKG2) 101097420(PRKG1)
PYU121016604(PRKG1) 121033641(PRKG2)
PBG122478735(PRKG2) 122492656(PRKG1)
PTG102949245(PRKG2) 102969150(PRKG1)
PPAD109255410(PRKG1) 109276981(PRKG2)
AJU106969513(PRKG1) 106976911(PRKG2)
HHV120222860(PRKG2) 120235955(PRKG1)
BTA282004(PRKG1) 533330(PRKG2)
BOM102269763(PRKG2) 102270503 102279305(PRKG1)
BIU109560622(PRKG2)
BBUB102405676(PRKG2) 102407722(PRKG1)
CHX102172135(PRKG2) 102182753(PRKG1)
OAS101113758(PRKG2) 443010(PRKG1)
ODA120861498(PRKG2) 120873771(PRKG1)
CCAD122428219(PRKG2) 122446215(PRKG1)
SSC100512796(PRKG2) 733640(PRKG1)
CFR102509252(PRKG1) 102519263(PRKG2)
CBAI105081869(PRKG1) 105084003(PRKG2)
CDK105085256(PRKG1) 105091814(PRKG2)
VPC102525406(PRKG2) 102528698(PRKG1)
BACU103012801(PRKG1) 103013933(PRKG2)
LVE103071917(PRKG1) 103091057(PRKG2)
OOR101279276(PRKG1) 101280012(PRKG2)
DLE111172539(PRKG1) 111187663(PRKG2)
PCAD102985621(PRKG2) 102991499(PRKG1)
PSIU116741389(PRKG1) 116754313(PRKG2)
ECB100060358(PRKG2) 100071872(PRKG1)
EPZ103549039(PRKG2)
EAI106828068(PRKG2) 106847454(PRKG1)
MYB102255009(PRKG1) 102258852(PRKG2)
MYD102770749(PRKG2)
MMYO118670010(PRKG1) 118670506(PRKG2)
MLF102423140(PRKG2)
MNA107537152(PRKG2) 107543282(PRKG1)
PKL118704664(PRKG2) 118719245(PRKG1)
HAI109387521(PRKG1) 109387927(PRKG2)
DRO112307314(PRKG1) 112319697(PRKG2)
SHON118990410(PRKG2) 119001529(PRKG1)
AJM119056901(PRKG2) 119057172
PDIC114493410(PRKG2) 114496021(PRKG1)
PHAS123828671(PRKG1) 123831363(PRKG2)
MMF118632751(PRKG1) 118635511(PRKG2)
RFQ117021894(PRKG2) 117035919(PRKG1)
PALE102884723(PRKG1) 102894554(PRKG2)
PGIG120588263(PRKG2) 120609370(PRKG1)
PVP105292433(PRKG2) 105293145(PRKG1)
RAY107515478(PRKG1) 107516479(PRKG2)
MJV108396587(PRKG2)
TOD119260972(PRKG2)
SARA101538623(PRKG1) 101542063(PRKG2)
LAV100657163(PRKG2) 100662471(PRKG1)
TMU101346076
DNM101417452(PRKG1) 101439805(PRKG2)
MDO100014568(PRKG2) 100023016(PRKG1)
GAS123234434(PRKG1) 123252215(PRKG2)
SHR100927283(PRKG2) 100928746(PRKG1)
PCW110199927(PRKG1) 110209720(PRKG2)
OAA100073431(PRKG1) 100082499(PRKG2)
GGA100859181(PRKACA) 423682(PRKG1) 428753(PRKG2)
PCOC116230675 116231090(PRKG2) 116234759(PRKG1)
MGP100540173(PRKG1) 100541294(PRKG2) 100544740
CJO107312321 107313465(PRKG2) 107315639(PRKG1)
NMEL110390491(PRKG1) 110396408 110397428(PRKG2)
APLA101790644(PRKG2) 101802614(PRKG1)
ACYG106030263(PRKG1) 106041906(PRKG2)
AFUL116488259 116489089(PRKG2) 116491070(PRKG1)
TGU100229896(PRKG1) 100232260(PRKG2)
LSR110474019(PRKG1) 110480895(PRKG2)
SCAN103823826(PRKG1) 103826056(PRKG2)
PMOA120502746(PRKG2) 120507265(PRKG1)
OTC121336109(PRKG1) 121339894(PRKG2)
PRUF121354020(PRKG2) 121357353(PRKG1)
GFR102041315(PRKG1) 102042278(PRKG2)
FAB101813345(PRKG2) 101816835(PRKG1)
PHI102105641(PRKG1) 102108417(PRKG2)
PMAJ107203574(PRKG2) 107207071(PRKG1)
CCAE111928808(PRKG2)
CCW104695105(PRKG1) 104697218(PRKG2)
ETL114059161(PRKG2) 114065114(PRKG1)
ZAB102074710(PRKG2) 102075463(PRKG1)
FPG101914750(PRKG1) 101916682 101918759(PRKG2)
FCH102051167(PRKG1) 102055004(PRKG2) 106631485
CLV102089346(PRKG2) 102098659(PRKG1)
EGZ104125151(PRKG1) 104133983(PRKG2)
NNI104013515(PRKG1) 104021251(PRKG2)
ACUN113479638(PRKG2) 113481922(PRKG1)
TALA104363723(PRKG2) 104364583(PRKG1) 116959621
PADL103913713(PRKG2)
ACHC115339981(PRKG2) 115348087(PRKG1) 115351043
AAM106491038(PRKG2)
AROW112973322(PRKG1) 112977374(PRKG2)
NPD112948419(PRKG1) 112954775(PRKG2)
DNE112981624(PRKG1) 112992291(PRKG2)
ASN102372581 102375122(PRKG2) 102385836(PRKG1)
AMJ102560332(PRKACA) 102570800(PRKG2) 102573015(PRKG1)
CPOO109309532(PRKG2) 109312524(PRKG1)
GGN109290935(PRKG1) 109297118(PRKG2)
CMY102942713(PRKG1)
CPIC101953224(PRKG1) 103305918(PRKG2)
TST117879767(PRKG1)
MRV120409369(PRKG1)
ACS100561246(prkg2) 103282038
PVT110084111(PRKG2) 110087006
SUND121919531 121926226(PRKG1) 121931735(PRKG2)
PBI103050448(PRKG2) 103060529 103064237
PMUR107286453 107303184(PRKG2)
TSR106545902 106547680(PRKG2)
PGUT117667640 117670643(PRKG1) 117673681(PRKG2)
VKO123018460(PRKG1) 123018727 123022846(PRKG2)
PMUA114595005 114597269(PRKG1) 114604385(PRKG2)
ZVI118083662(PRKG2) 118096161(PRKG1)
GJA107114871(PRKG2)
STOW125437653(PRKG1) 125440352(PRKG2) 125443595
XLA108696071 108696263 108697216 108697357(prkg1.S) 444025(prkg2.L)
XTR100494278(prkg1) 100497736(prkg2) 100498055
NPR108789074(PRKG2) 108797031(PRKG1)
RTEM120908941 120914409(PRKG2) 120947083(PRKG1)
BBUF120991655(PRKG2) 121003777(PRKG1) 121005082
BGAR122927516(PRKG2) 122940153(PRKG1) 122941006
DRE100125912(prkg2) 326020(si:dkey-121j17.5) 394005(prkg1a) 556339 566430(prkg1b)
SRX107708387 107708873 107727357 107731507 107744862 107746786
SANH107654050 107660531 107661254 107663377(prkg2) 107680302 107695529 107699307
SGH107554918 107557353(prkg1) 107586507 107599184 107602032
CCAR109078441 109090195 109090782 109108300
CAUA113049125 113056342 113057217 113063503 113077808 113111947 113112406 113112450
PPRM120461784(prkg2) 120462257(prkg1a) 120474479(prkg1b) 120479266(prkg3) 120479323
MAMB125254981(prkg1b) 125266993(prkg2) 125276687 125277225(prkg1a) 125277724(prkg3)
IPU108255985(prkg2) 108261320(prkg3) 108263686 108274270(prkg1b)
PHYP113527432 113529209 113537052(prkg2) 113538666
SMEO124375611(prkg1a) 124380680(prkg2) 124388860(prkg1b) 124394485 124401374(prkg3)
TFD113637633(prkg2) 113639764 113639906(prkg1a) 113649386(prkg1b) 113654820(prkg3)
AMEX103022723 103030142(prkg2) 103041230 103047830(prkg1)
EEE113577006(prkg1) 113585394 113589804 113591915
TRU101061256(prkg1) 101071377 101074431(prkg2) 105419048
TNGGSTEN00016387G001 GSTEN00030356G001
LCO104921979 104927466 104929951(prkg2) 104939827
NCC104947339 104954051 104955830 104955882
CGOB115003587 115013763(prkg2) 115019815 115020192(prkg1)
ELY117247991 117252905(prkg2) 117270421(prkg3)
PLEP121944718(prkg2) 121954433 121954489 121956012(prkg3)
SLUC116050373 116054106(prkg2) 116055147 116066486(prkg3)
ECRA117945406(prkg2) 117960504 117960788 117961240(prkg3)
PFLV114555686(prkg2) 114571723 114572507
GAT120807891(prkg3) 120813110 120820788
PPUG119195391(prkg3) 119214369 119224835(prkg2)
MSAM119892004(prkg2) 119908424(prkg3) 119917222
CUD121510051(prkg2) 121511176 121511336 121521080(prkg3)
ALAT119012153(prkg3) 119020289(prkg2) 119033457 119033936
MZE101466538 101471197(prkg2) 101479945
ONL100694992 100699113(prkg2) 100708987
OAU116310793(prkg3) 116333376(prkg2) 116333752
OLA100049290(prkg1) 101158535(prkg2) 101165996 101173830
OML112137683(prkg2) 112158429(prkg3) 112161926 112161974(prkg1b)
XMA102216397 102230306(prkg2) 102235247
XCO114138474 114153990(prkg2) 114158207
XHE116713518 116729132(prkg2) 116733691
PRET103457572 103469805(prkg2) 103476798
PFOR103133523 103134891(prkg2) 103134980 103138603
PLAI106934820(prkg2) 106935940 106947667 106957396
PMEI106906174 106915466 106922336(prkg2) 106928310 106929127
GAF122825526(prkg3) 122828661(prkg2) 122842979
CVG107083363 107083975(prkg2) 107098368
CTUL119785128(prkg3) 119785444(prkg2) 119790862
GMU124859212 124875514 124877400(prkg2) 124882369(prkg3)
NFU107375493 107376029 107377464 107386061(prkg2)
KMR108239119 108240136(prkg3) 108242381 108244533(prkg2)
ALIM106513507(prkg1) 106513735 106516936 106525434(prkg2) 106528217
NWH119407520 119413007 119413136(prkg2) 119418541(prkg3) 119423874
AOCE111565792(prkg2) 111568230 111575530(prkg1) 111586601
CSEM103380827 103386981 103387682(prkg1) 103397539(prkg2)
POV109629155 109632737
SSEN122762998(prkg2) 122764933 122782184 122783714(prkg3)
HHIP117758431(prkg3) 117767429(prkg2) 117775114 117775561
HSP118099599(prkg3) 118100879 118115516(prkg2) 118119160 118119306 118125824
LCF108887140(prkg2) 108895314 108895629 108897326
SDU111216303 111228005(prkg2) 111235208
SLAL111650595 111653026 111654602 111660882(prkg2) 111670023(prkg1)
XGL120789174(prkg3) 120796378 120796544 120805415(prkg2)
HCQ109516694 109520050 109526918(prkg2) 109528789
BPEC110155390 110157105 110158150 110160457
MALB109952723 109957341(prkg2) 109962157(prkg1)
BSPL114850179(prkg3) 114862959(prkg2) 114870401
SASA106571758 106576682 106607930 106608672
OTW112217699 112232971 112253523 112253870
OMY110491369 110498977 110502406 110502467 110522345 110527939 110528926 110529892
OGO123991020 123995194 124037210 124038255 124040042(prkg1b) 124040785 124041256 124048150
ONE115106350 115108024 115113223 115113268 115135103 115135178 115139298 115144061
SALP111951584 111954366 111973400 111977420
SNH120017414 120017651 120024381 120029745(prkg1b) 120045630 120045866 120046129
ELS105006031 105007647(prkg2) 105010732
SFM108924066 108932765 108938469(prkg2) 108939676(prkg1) 108942712
PKI111839266 111841262 111853690(prkg1)
AANG118217691 118217808 118221272(prkg1b) 118229259(prkg3) 118237345(prkg2)
LOC102684201(prkg1) 102689239 102694398(prkg2) 102697784 102698203
PSPA121300010(prkg2) 121303213 121317145(prkg3) 121318794 121321863 121325426 121325521
ARUT117397688 117410442(prkg3) 117414972 117417630 117418513 117962943
LCM102345412 102357627 102361824(PRKG2)
CMK103180874(prkg2) 103180883(prkg1b) 103181471 103190998
RTP109923944 109924169 109927508
BFO118411480 118412576 118412578
BBEL109466828 109478278 109478342
CIN100176673 100179064 100184124
SCLV120329981 120336876 120347122 120347480
SPU589462
APLC110973758 110982046
DMEDmel_CG10033(for) Dmel_CG3324(Pkg21D) Dmel_CG4839(CG4839)
DER6540897 6541099 6542539
DSE6613265 6617296
DSIDsimw501_GD22740(Dsim_GD22740) Dsimw501_GD22942(Dsim_GD22942) Dsimw501_GD23660(Dsim_GD23660)
DYADyak_GE14825 Dyak_GE15942 Dyak_GE18902
DAN6497481 6497690
DSR110178188 110182603 110187360
DPODpse_GA10020 Dpse_GA17377 Dpse_GA18468
DPE6588824 6589026 6595699
DMN108162046 108162419 108163582
DWI6642441 6644123
DGR6561993 6562037 6566754
DMODmoj_GI17764 Dmoj_GI18016
DAZ108609997 108611824
DNV115562010 115563626
DHE111599114 111601364
DVI6628026 6628367
CCAT101451635 101452607
BOD106615054 106617651
MDE101894230 101894351 101900584
SCAC106085521 106093532
LCQ111677667 111681972
LSQ119603018 119610902
HIS119646149 119651059 119651726
AGAAgaP_AGAP008585 AgaP_AGAP008863 AgaP_AGAP009798
ACOZ120955578 120956569 120959490
AARA120899642 120900505 120902572
ASTE118512489 118513432 118513550
AAG5567008 5569682 5577470
AALB109397574 109433057 109621380 109621502 115268590
CQUCpipJ_CPIJ006121
CPII120414069 120418422 120420968 120431661
CNS116337020 116338275
BCOO119075651 119077031 119082106
AME406092(For)
ACER107997323 108004011
ALAB122712172 122712332
BIM100744786
BBIF117213509
BVK117233582
BVAN117154791
BTER100628631
BPYO122574299 122577979
CCAL108631693
OBB114878681
MGEN117221657
NMEA116428630
CGIG122400917 122403435
SOC105202008
MPHA105835361
AEC105148710
ACEP105627059
PBAR105427696
VEM105562546
HST105180461
DQU106741445
CFO105255628
FEX115234366 115240325
LHU105678094
PGC109861390
OBO105280702
PCF106784179
PFUC122516023 122522834
VPS122628887 122632580
NVI100117965 100119839
CSOL105361340
TPRE106649867 106657344
MDL103578414
CGLO123265708 123265709 123268458
FAS105265589 105269094 105269097
DAM107037098 107039744 107039745
AGIF122849834 122857197
CCIN107265986 107267830 107267842
TCA657149
DPA109536702 109546365
SOY115877055 115877063 115883044 115883833
ATD109595188 109601774 109603865
CSET123311494 123312035 123312094 123315992 123317286 123317590
AGB108903623 108908291 108909709 108916198
LDC111508658 111508661 111508668 111509749 111511298
NVL108561083 108561485
APLN108737706 108738730 108739815 108743355 112906357
PPYR116170816 116180394 116181607
OTU111424894 111426555 111427377 111427906
BMOR692605(PKG-I)
BMAN114250737
MSEX115443172 115455815
DPLKGM_208453
BANY112046535 112049408
PMAC106712155
PPOT106105142 106109172
PXU106126670 106128323
PRAP110996423 110996662
ZCE119834783 119839976
HAW110376116
TNL113492093
SLIU111351847 111353670 111362670
OFU114351338 114353143
PXY105381837
API100168151
DNX107170171
AGS114124896
RMD113560773
BTAB109030563 109043112
DCI103507911 103516942
CLEC106662224 106663991
HHAL106678864 106681618
NLU111048384 111048592
PHUPhum_PHUM189890 Phum_PHUM596920
FOC113202771 113212626
TPAL117648659 117650290
ZNE110836511 110837257
CSEC111867470 111868652
FCD110847879
DPXDAPPUDRAFT_194528 DAPPUDRAFT_207381
DMK116930926 116932040 116932149
PVM113813818
PJA122247724 122249836 122251530 122261895
PCHN125041886 125042756
HAME121864608 121880177
PCLA123757902 123758453
PTRU123499641 123520209
HAZT108666480 108679848
EAF111700247 111700258 111701474 111713529
LSM121126665
PPOI119097726 119101854 119101965 119102078
ISCIscW_ISCW007896
DSV119436380 119445576
RSAN119389391 119401322
RMP119161615 119161732
VDE111243669
VJA111266620
TUT107363105
DPTE113790699
DFR124490296 124496655
CSCU111625343
PTEP107436702 107446305
SDM118180849 118183323 118186346 118201394 118202144
CELCELE_F55A8.2(egl-4)
CBRCBG_08401(Cbr-pkg-1)
LGILOTGIDRAFT_127769 LOTGIDRAFT_210612
PCAN112565934 112573499
BGT106065352 106067606
GAE121378627 121378889
HRF124132484 124139612
HRJ124277971 124285481
CRG105335784 105345094
MYI110449619 110451175
PMAX117328060 117334498
MMER123563923 123564110
OBI106880808
OSN115214224
LAK106156342 106181988
SMMSmp_168670
SHXMS3_0017732
NVE5509991
EPA110249033
ATEN116288998 116289897
AMIL114960266
PDAM113677276
SPIS111344883
XEN124438049 124439048
HMG100201371
TADTRIADDRAFT_30166
VCNVOLCADRAFT_81219 VOLCADRAFT_97912
CSLCOCSUDRAFT_35741
CVRCHLNCDRAFT_49225
APROF751_6750
OTAOT_ostta13g01130
BPGBathy04g01910
MISMICPUN_104866(CL-PK2)
MPPMICPUCDRAFT_33413
PFAPF3D7_1436600
PFDPFDG_01207 PFDG_03615
PFHPFHG_00276 PFHG_04513
PREIPRSY57_1435900
PGABPGSY75_1436600
PYOPY17X_1009800
PCBPCHAS_100910(PC000298.03.0)
PBEPBANKA_1008200
PVVPVVCY_0800870
PKNPKNH_0423200
PVXPVX_084705
PCYPCYB_132230
TANTA04955
TPVTP03_0511
BBIGBBBOND_0406010
CPVcgd8_750
CHOChro.80094
TETTTHERM_00013270 TTHERM_00105520 TTHERM_00193700 TTHERM_00442770
PTMGSPATT00017822001 GSPATT00038158001
FCYFRACYDRAFT_263989
TPSTHAPSDRAFT_1553 THAPSDRAFT_21108
AAFAURANDRAFT_19287 AURANDRAFT_63526
PIFPITG_11102
SMAGAN936_03545
SMAZLH19_17420
SPHUSPPYR_2707
 » show all
Reference
1  [PMID:186778]
  Authors
Gill GN, Holdy KE, Walton GM, Kanstein CB.
  Title
Purification and characterization of 3':5'-cyclic GMP-dependent protein kinase.
  Journal
Proc Natl Acad Sci U S A 73:3918-22 (1976)
DOI:10.1073/pnas.73.11.3918
Reference
2  [PMID:15312978]
  Authors
Murthy KS.
  Title
Modulation of soluble guanylate cyclase activity by phosphorylation.
  Journal
Neurochem Int 45:845-51 (2004)
DOI:10.1016/j.neuint.2004.03.014
Reference
3  [PMID:12933804]
  Authors
Richie-Jannetta R, Francis SH, Corbin JD.
  Title
Dimerization of cGMP-dependent protein kinase Ibeta is mediated by an extensive amino-terminal leucine zipper motif, and dimerization modulates enzyme function.
  Journal
J Biol Chem 278:50070-9 (2003)
DOI:10.1074/jbc.M306796200
Reference
4  [PMID:9395542]
  Authors
Zhao J, Trewhella J, Corbin J, Francis S, Mitchell R, Brushia R, Walsh D.
  Title
Progressive cyclic nucleotide-induced conformational changes in the cGMP-dependent protein kinase studied by small angle X-ray scattering in solution.
  Journal
J Biol Chem 272:31929-36 (1997)
DOI:10.1074/jbc.272.50.31929
Other DBs
ExplorEnz - The Enzyme Database: 2.7.11.12
IUBMB Enzyme Nomenclature: 2.7.11.12
ExPASy - ENZYME nomenclature database: 2.7.11.12
BRENDA, the Enzyme Database: 2.7.11.12
CAS: 141588-27-4
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