| Entry |
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| Name |
UTP---hexose-1-phosphate uridylyltransferase;
galactose-1-phosphate uridylyltransferase;
galactose 1-phosphate uridylyltransferase;
alpha-D-galactose 1-phosphate uridylyltransferase;
galactose 1-phosphate uridyltransferase;
UDPgalactose pyrophosphorylase;
uridine diphosphate galactose pyrophosphorylase;
uridine diphosphogalactose pyrophosphorylase
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| Class |
Transferases;
Transferring phosphorus-containing groups;
Nucleotidyltransferases
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| Sysname |
UTP:alpha-D-hexose-1-phosphate uridylyltransferase
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| Reaction(IUBMB) |
UTP + alpha-D-galactose 1-phosphate = diphosphate + UDP-alpha-D-galactose [RN: R00502]
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| Reaction(KEGG) |
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| Substrate |
UTP [CPD: C00075];
alpha-D-galactose 1-phosphate [CPD: C00446]
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| Product |
diphosphate [CPD: C00013];
UDP-alpha-D-galactose [CPD: C00052]
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| Comment |
alpha-D-Glucose 1-phosphate can also act as acceptor, but more slowly.
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| History |
EC 2.7.7.10 created 1961
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| Pathway |
| ec00520 | Amino sugar and nucleotide sugar metabolism |
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| Reference |
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| Authors |
ISSELBACHER KJ. |
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| Title |
A mammalian uridinediphosphate galactose pyrophosphorylase. |
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| Journal |
J Biol Chem 232:429-44 (1958) |
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| Reference |
|
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| Authors |
KALCKAR HM. |
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| Title |
The role of phosphoglycosyl compounds in the biosynthesis of nucleosides and nucleotides. |
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| Journal |
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| Reference |
|
|---|
| Authors |
Lee L, Kimura A, Tochikura T. |
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| Title |
Purification and properties of UDP-glucose (UDP-galactose) pyrophosphorylase from Bifidobacterium bifidum. |
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| Journal |
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| Reference |
|
|---|
| Authors |
Lobelle-Rich PA, Reeves RE. |
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| Title |
Separation and characterization of two UTP-utilizing hexose phosphate uridylyltransferases from Entamoeba histolytica. |
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| Journal |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 2.7.7.10 |
| ExPASy - ENZYME nomenclature database: | 2.7.7.10 |
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| LinkDB |
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