KEGG ENZYME: 2.7.7.30

ENZYME: 2.7.7.30

Entry

EC 2.7.7.30                 Enzyme

Name

fucose-1-phosphate guanylyltransferase;
GDP fucose pyrophosphorylase;
guanosine diphosphate L-fucose pyrophosphorylase;
GDP-L-fucose pyrophosphorylase;
GDP-fucose pyrophosphorylase;
GTP:L-fucose-1-phosphate guanylyltransferase

Class

Transferases;
Transferring phosphorus-containing groups;
Nucleotidyltransferases

Sysname

GTP:beta-L-fucose-1-phosphate guanylyltransferase

Reaction(IUBMB)

GTP + beta-L-fucose 1-phosphate = diphosphate + GDP-L-fucose [RN:R01951]

Reaction(KEGG)

R01951

Substrate

GTP [CPD:C00044];
beta-L-fucose 1-phosphate [CPD:C02985]

Product

diphosphate [CPD:C00013];
GDP-L-fucose [CPD:C00325]

History

EC 2.7.7.30 created 1972

Pathway

ec00051

Fructose and mannose metabolism

ec00520

Amino sugar and nucleotide sugar metabolism

ec01100

Metabolic pathways

Orthology

K00976

fucose-1-phosphate guanylyltransferase

K25314

fucokinase / fucose-1-phosphate guanylyltransferase

K25315

arabinokinase / fucokinase / arabinose-1-phosphate guanylyltransferase / fucose-1-phosphate guanylyltransferase

Genes

HSA:	8790(FPGT)

PTR:	100533984(FPGT)

PPS:

100990811

GGO:	109023043(FPGT)

PON:	100173506(FPGT)

PPYG:

129033554(FPGT)

SSYN:

134733643(FPGT)

MCC:	100533986(FPGT)

MCF:	102134248(FPGT)

MTHB:

126940918

MNI:	105482650(FPGT)

CSAB:

103224607(FPGT)

CATY:

105595859(FPGT)

PANU:

100999367(FPGT)

TGE:	112632015(FPGT)

MLEU:

105537995(FPGT)

RRO:	104676324(FPGT)

RBB:	108527595(FPGT)

TFN:	117092104(FPGT)

PTEH:

111540846(FPGT)

CANG:

105508111(FPGT)

CJC:	100414295(FPGT)

SBQ:	104652770(FPGT)

CIMI:

108306655(FPGT)

ANAN:

105710307(FPGT)

CSYR:

103261653(FPGT)

MMUR:

105868949(FPGT)

LCAT:

123635513(FPGT)

PCOQ:

105822635(FPGT)

OGA:	105886445(FPGT)

MMU:	75540(Fpgt)

MCAL:

110290858(Fpgt)

MPAH:

110320041(Fpgt)

MCOC:

116093978(Fpgt)

ANU:	117706869(Fpgt)

MUN:	110540835(Fpgt)

CGE:	100769105(Fpgt)

MAUA:

101838696(Fpgt)

PROB:

127230374(Fpgt)

PLEU:

114702494(Fpgt)

MORG:

121447248(Fpgt)

MFOT:

126506166

AAMP:

119801277(Fpgt)

NGI:	103750548(Fpgt)

HGL:	106009104(Fpgt)

CPOC:

100718633(Fpgt)

CCAN:

109681613(Fpgt)

DORD:

105986186(Fpgt)

DSP:	122109225(Fpgt)

PLOP:

125355304(Fpgt)

NCAR:

124986725

MMMA:

107146419(Fpgt)

OCU:	100533991(FPGT)

OPI:	101517689(FPGT)

TUP:	102502767(FPGT)

GVR:	103606710(FPGT)

CFA:	100533995(FPGT)

CLUD:

112641049(FPGT)

VVP:	112934592(FPGT)

VLG:	121487664(FPGT)

NPO:	129520167(FPGT)

AML:	109488331(FPGT)

UMR:	121099733(FPGT)

UAH:	113254527(FPGT)

UAR:	123795311(FPGT)

ELK:

111143134

LLV:

125097665

MPUF:

106003372(FPGT)

MNP:	132001023(FPGT)

MLK:	131809166(FPGT)

NVS:

122900093

ORO:	101369461(FPGT)

EJU:	114208463(FPGT)

ZCA:	113929811(FPGT)

MLX:	118019270(FPGT)

NSU:	110570143(FPGT)

LWW:	102738625(FPGT)

FCA:	101085816(FPGT)

PYU:	121027319(FPGT)

PCOO:

112848908(FPGT)

PBG:	122480640(FPGT)

PVIV:

125173625(FPGT)

LRUF:

124515113

PTG:	102971036(FPGT)

PPAD:

109266675(FPGT)

PUC:

125912509

AJU:

106984974

HHV:	120226013(FPGT)

BTA:	100138313(FPGT)

BOM:	102287603(FPGT)

BIU:	109556163(FPGT)

BBUB:

102410344(FPGT)

BBIS:

104995532(FPGT)

CHX:	102170656(FPGT)

OAS:	105601872(FPGT)

BTAX:

128044650(FPGT)

ODA:	120856989(FPGT) 120861097

CCAD:

122436818(FPGT)

SSC:	100513664(FPGT)

CFR:	102519461(FPGT)

CBAI:

105075534(FPGT)

CDK:	105096643(FPGT)

VPC:	102526095(FPGT)

BACU:

103011255(FPGT)

BMUS:

118900063(FPGT)

LVE:	103077057 103088164(FPGT)

OOR:	105747714(FPGT)

DLE:	111178416(FPGT)

PCAD:

102989447(FPGT)

PSIU:

116738841(FPGT)

NASI:

112392774(FPGT)

ECB:	100533993(FPGT)

EPZ:	103554146(FPGT)

EAI:	106824902(FPGT)

MYB:	102249837(FPGT)

MYD:	102761555(FPGT)

MMYO:

118676384(FPGT)

MLF:	102424786(FPGT)

MDT:	132230939(FPGT)

PKL:	118723396(FPGT)

EFUS:

103284126(FPGT)

MNA:	107540118(FPGT)

DRO:

112309269

SHON:

118984425(FPGT)

AJM:	119046143(FPGT)

PDIC:

114496619(FPGT)

PHAS:

123816383(FPGT)

MMF:	118626998(FPGT)

PPAM:

129065614(FPGT)

HAI:	109383506(FPGT)

RFQ:	117027764(FPGT)

PALE:

102891717(FPGT)

PGIG:

120583232(FPGT)

PVP:	105295868(FPGT)

RAY:	107511006(FPGT)

MJV:	108401569(FPGT)

TOD:	119235317(FPGT)

SARA:

105942727(FPGT)

SETR:

126006664(FPGT)

LAV:	104846008(FPGT)

TMU:

105755965

DNM:	105744903(FPGT)

MDO:	100533988(FPGT)

GAS:	123247546(FPGT)

SHR:	100927102(FPGT)

AFZ:

127563148

PCW:	110195722(FPGT)

TVP:	118847935(FPGT)

OAA:	100074992(FPGT)

GGA:	100533998(FPGT)

PCOC:

116236328(FPGT)

MGP:	109363689(FPGT)

CJO:	107317799(FPGT)

TPAI:

128072634(FPGT)

LMUT:

125692982(FPGT)

NMEL:

110402682(FPGT)

APLA:

101793711(FPGT)

ACYG:

106043582(FPGT)

CATA:

118256985(FPGT)

AFUL:

116491853(FPGT)

TGU:	100218973(FPGT)

LSR:	110477126(FPGT)

SCAN:

108961819(FPGT)

PMOA:

120499674(FPGT)

OTC:	121332665(FPGT)

PRUF:

121354676(FPGT)

GFR:	102035647(FPGT)

FAB:	101818059(FPGT)

OMA:	130256023(FPGT)

PHI:	102112093(FPGT)

PMAJ:

107207943(FPGT)

CCAE:

111932878(FPGT)

CCW:	104695484(FPGT)

CBRC:

103612913(FPGT)

ZLE:	135450915(FPGT)

ACHL:

103800494(FPGT)

SVG:	106863181(FPGT)

MMEA:

130586539(FPGT)

HRT:	120756525(FPGT)

SATI:

136365036(FPGT)

FPG:	101917539(FPGT)

FCH:	114015605(FPGT)

CCRI:

104160010(FPGT)

NNT:	104403747(FPGT)

SHAB:

115611964(FPGT)

ACUN:

113482778(FPGT)

TALA:

104361363(FPGT)

ACHC:

115348878(FPGT)

HALD:

104317718(FPGT)

HLE:	104828087(FPGT)

AGEN:

126041858

GCL:

127019099

CSTI:

104556479(FPGT)

MNB:	103775860(FPGT)

AVIT:

104280922(FPGT)

BRHI:

104494401(FPGT)

EGZ:	104123857(FPGT)

NNI:	104009312(FPGT)

PCAO:

104042404(FPGT)

PADL:

103914059(FPGT)

AFOR:

103907167(FPGT)

FGA:	104083254(FPGT)

GSTE:

104255764(FPGT)

CLV:	102093057(FPGT)

MUI:	104541576(FPGT)

PGUU:

104470977(FPGT)

PLET:

104618376(FPGT)

EHS:	104513981(FPGT)

CMAC:

104482191(FPGT)

CUCA:

104066606(FPGT)

TEO:	104383435(FPGT)

BREG:

104641252(FPGT)

OHA:	104337250(FPGT)

ACAR:

104525836(FPGT)

CVF:	104285493(FPGT)

RTD:	128914158(FPGT)

AAM:	106486500(FPGT)

AROW:

112970267(FPGT)

NPD:	112950010(FPGT)

TGT:	104574119(FPGT)

DNE:	112982271(FPGT)

ASN:	102386171(FPGT)

AMJ:	102572405(FPGT)

CPOO:

109307593

GGN:

109305407

PSS:	102460460(FPGT)

CMY:	102944083(FPGT)

CCAY:

125641949(FPGT)

DCC:	122455378(FPGT)

TST:	117882208(FPGT)

CABI:

116825845(FPGT)

MRV:	120369673(FPGT)

ACS:	103279374(fpgt)

ASAO:

132774046

PVT:	110079520(FPGT)

SUND:

121928998(FPGT)

PBI:	103062201(FPGT)

PMUR:

107285062(FPGT)

CTIG:

120300772(FPGT)

TSR:	106540235(FPGT)

PGUT:

117674949(FPGT)

APRI:

131194877(FPGT)

PTEX:

113436048(FPGT)

NSS:	113419773(FPGT)

VKO:	123028674(FPGT)

PMUA:

114598440

PRAF:

128415608(FPGT)

ZVI:	118088797(FPGT)

HCG:	128322244(FPGT)

GJA:	107116977(FPGT)

STOW:

125433036(FPGT)

EMC:	129329895(FPGT)

XLA:	100189576(fpgt.L)

XTR:	100485861(fpgt) 116410499

NPR:	108804953(FPGT)

RTEM:

120946021(FPGT)

BBUF:

120978520(FPGT)

BGAR:

122943021(FPGT)

MUO:	115471774(FPGT)

DRE:	553792(fpgt)

SRX:	107743844(fpgt)

SANH:

107699845

SGH:	107548491 107585822

CAUA:

113107101

CGIB:

127963836

PTET:

122350491(fpgt)

LROH:

127169530(fpgt)

OMC:	131545561(fpgt)

PPRM:

120482196(fpgt)

RKG:	130086115(fpgt)

CIDE:

127517473

CERY:

137026961(fpgt)

MASI:

127424209

TROS:

130568233(fpgt)

TDW:	130407112(fpgt)

MANU:

129413898(fpgt)

IPU:

108266010

IFU:	128608261(fpgt)

PHYP:

113525511(fpgt)

SMEO:

124399925(fpgt)

TRN:	134318614(fpgt)

AMEX:

103031681(fpgt)

CMAO:

118813938(fpgt)

EEE:	113586873(fpgt)

CHAR:

105895229(fpgt)

TRU:	101065093(fpgt)

TFS:	130528951(fpgt)

TNG:	GSTEN00020215G001

LCO:	109136587(fpgt)

NCC:	104966259(fpgt)

TBEN:

117496218(fpgt)

CGOB:

115007271(fpgt)

PGEO:

117445345(fpgt)

GACU:

117550936(fpgt)

EMAC:

134869702(fpgt)

ELY:	117253771(fpgt)

EFO:	125896121(tnni3k)

SLUC:

116063333(fpgt)

ECRA:

117950820(fpgt)

ESP:	116695859(fpgt)

PFLV:

114561135(fpgt)

GAT:	120824438(fpgt)

PPUG:

119216720(fpgt)

AFB:	129094367(fpgt)

CLUM:

117730180(tnni3k)

PSWI:

130193672(fpgt)

MSAM:

119900832 119900889

SCHU:

122877803(fpgt)

CUD:	121512296(fpgt)

ALAT:

119028189(fpgt)

MZE:	101481658(fpgt)

ONL:	100704223(fpgt)

OAU:	116333311(fpgt)

OLA:	101161043(fpgt)

OML:	112136849(fpgt)

CSAI:

133458090(fpgt)

XMA:	102216987(fpgt)

XCO:	114151231(fpgt)

XHE:	116726103(fpgt)

PRET:

103463603(fpgt)

PFOR:

103142556(fpgt)

PLAI:

106963637(fpgt)

PMEI:

106925912(fpgt)

GAF:	122838231(fpgt)

PPRL:

129374534(fpgt)

CVG:	107081983(fpgt)

CTUL:

119772962(fpgt)

GMU:	124873847(tnni3k)

NFU:	107393247(fpgt)

KMR:	108230810(fpgt)

ALIM:

106513880(fpgt)

AOCE:

111583911(fpgt)

MCEP:

125009913(fpgT)

CSEM:

103393650(fpgt)

POV:	109625635(fpgt)

SSEN:

122780652(fpgt)

HHIP:

117760408(fpgt)

HSP:	124854663(fpgt)

PPLT:

128448279(fpgt)

SMAU:

118318333(fpgt)

LCF:

108877374

SDU:	111232156(fpgt)

SLAL:

111656323(fpgt)

XGL:	120790530(fpgt)

HCQ:	109532336(fpgt)

SSCV:

125970663

SBIA:

133503108(fpgt)

PEE:	133406642(fpgt)

PTAO:

133481145(fpgt)

MALB:

109964045

BSPL:

114853903(fpgt)

SJO:	128362163(fpgt)

SASA:

100195329(fpgt)

STRU:

115158009

OTW:	112250652(fpgt)

OMY:	110524057(fpgt)

OGO:	123996755(fpgt)

ONE:	115107366(fpgt)

OKI:	109902293(fpgt)

OKE:	118387307(fpgt)

SALP:

111976082

SNH:

120054404

CCLU:

121576563(fpgt)

ELS:	105006474(fpgt)

SFM:	108934185(fpgt)

PKI:	111855206(fpgt)

AANG:

118226255(fpgt)

LOC:	102695472(fpgt)

PSPA:

121331072(fpgt)

ARUT:

117405409(fpgt)

PSEX:

120515290 120515291

LCM:	102350282(FPGT)

CMK:	103174745(fpgt)

RTP:	109937833(fpgt)

CPLA:

122554092(fpgt)

HOC:	132819210(fpgt)

LERI:

129694449(fpgt)

BFO:

118419618

BBEL:

109468057

CIN:

100176066

SCLV:

120328011

SPU:	583165 757180

LPIC:

129261853

APLC:

110975895

ARUN:

117293967

AJC:

117123893

SKO:

100368882

DPX:	DAPPUDRAFT_309524

DMK:

116919200

DPZ:

124344061

PVM:

113817277

PJA:

122250078

PCHN:

125036127

PMOO:

119594149

HAME:

121864959

PCLA:

123761756

CQD:

128688337

PTRU:

123518258

MNZ:

135214726

HAZT:

108680617

EAF:

111718468

TCF:

131884571

PPOI:

119107348

DSV:

119450040

RSAN:

119383044

RMP:

119170240

VDE:

111247752

VJA:

111269630

CSCU:

111619484

CVS:

136982282

PTEP:

107447390

ABRU:

129981885

UDV:

129221953

SDM:

118190518

LPOL:

106461208

CEL:	CELE_K03H1.13(K03H1.13)

NAI:	NECAME_11598

HRO:	HELRODRAFT_67205

LGI:	LOTGIDRAFT_112785

PVUL:

126831097

PCAN:

112558636

BGT:

106058818

GAE:

121375963

HRF:

124144169

HRJ:

124269146

CRG:

105339002

CANU:

128191827

CVN:

111127223

OED:

125680505

MYI:

110459223

PMAX:

117329533

MCAF:

127714815

MMER:

123556520

RPHI:

132747139

DPOL:

127878440 127879227 127879604

MAEA:

128228233 128228283

OBI:

106880712

OSN:

115218636

LJP:

135473781

LAK:

106168917

LLON:

135493953

NVE:

116618002

ATEN:

116302230

ADF:

107347660

AMIL:

114969369

PDAM:

113670572

SPIS:

111328004

DGT:

114532314

XEN:

124441826

HMG:

100207743

HSY:

130657188

RES:

135692736

TAD:	TRIADDRAFT_24800

ATH:	AT1G01220(FKGP)

ALY:

9328144

CRB:

17876572

CSAT:

104738672 104754265 104759313

EUS:	EUTSA_v10006637mg

BRP:

103843778

BNA:	106352534 106377357

BOE:

106312465

RSZ:

108862914

THJ:

104815884

CPAP:

110808528

CIT:	102607405 127901096

CIC:	CICLE_v10018702mg

PVY:

116142159

MINC:

123223163

TCC:

18613941

GRA:

105763919

GHI:

121224126

GAB:

108479543

HSYR:

120131206

DZI:

111304857

EGR:	104445349 120286350

GMX:	100776147 100803620

GSJ:	114398035 114407822

PVU:	PHAVU_006G115200g

VRA:

106754135

VAR:

108343062

VUN:

114187899

VUM:

124830718

CCAJ:

109796650

APRC:

113861369

MTR:

11435147

TPRA:

123889547

CAM:

101489062

PSAT:

127132088

VVO:

131610762

LJA:

130731417

ADU:

107491927

AIP:

107646095

AHF:	112695289 112758493

LANG:

109333340

PCIN:

129291289

QSA:	O6P43_027403

FVE:

101313747

RCN:

112182084

PPER:

18785393

PMUM:

103332228

PAVI:

110757650

PDUL:

117617124

MDM:

103439376

MSYL:

126629529

PXB:

103927198

ZJU:

107423663

MNT:

21406234

CSV:

101204338

CMO:

103483166

BHJ:

120083429

MCHA:

111016303

CMAX:

111473620 111475081

CMOS:

111441674

CPEP:

111800352

RCU:

8282132

MEAN:

126686956

JCU:

105642816

HBR:

110632095

MESC:

110614294

POP:

7486785

PEU:

105135437

PALZ:

118041222

PNZ:

133682796

JRE:

109010378

CILL:

122299972

CAVE:

132187662

QSU:

111983257

QLO:

115955796

TWL:

120004064

VVI:

100258719

VRI:

117932264

SLY:

101258193

SPEN:

107007997

SOT:

102590041

SSTN:

125877598

SDUL:

129886432

CANN:

107839347

LBB:

132645416

NTA:	107766622 107817245

NSY:

104228145

NTO:

104121367

NAU:

109227812

INI:

109150877

ITR:

115996628

SIND:

105173828

OEU:

111409933

EGT:

105963921

SSPL:

121795310 121798840

SMIL:

130997336

SHIS:

125203888

APAN:

127261313

HAN:

110937555

ECAD:

122594409

LSV:

111894586

CCAV:

112526343

DCR:

108209637

CSIN:

114290101

RVL:

131334543

AEW:

130783685

BVG:

104907115

SOE:

110786573

CQI:	110713928 110731719

ATRI:

130809656

MOF:

131166894

NNU:

104604718

MING:

122081866

TSS:

122667273

PSOM:

113297710 113301503

OSA:

4331392

OBR:

102713062

OGL:

127768664

BDI:

100826076

ATS:

109785929

TDC:	119292137 119304223

TAES:

123093854 123099075 123106030

TUA:

125511496

LPER:

127297502

LRD:	124701109 124701231

SBI:

8078003

ZMA:

100381824

MFLO:

136535814

SITA:

101773659

SVS:

117840567

PVIR:

120647567 120687885

PHAI:

112878344

PDA:

103719462

EGU:

105043452

MUS:

103970309

ZOF:	121967564 122052800

DCT:

110094703

PEQ:

110030506

AOF:

109825030

MSIN:

131248553

ATR:

18447674

PPP:

112278448

MPP:	MICPUCDRAFT_57615

RIE:	OCT59_010414

MBR:	MONBRDRAFT_29613

SRE:	PTSG_06236

DDI:	DDB_G0285257(fpgt)

DPP:	DICPUDRAFT_82454

ACAN:

ACA1_001300

GTT:	GUITHDRAFT_111266

LMA:	LMJF_16_0440 LMJF_16_0480

LIF:	LINJ_16_0450 LINJ_16_0490

LDO:	LDBPK_160450

LMI:	LMXM_16_0440 LMXM_16_0480

LMAT:

92515636(LSCM1_05678)

LBZ:	LBRM_16_0500

LPAN:

LPMP_160480

LOI:	92361452(LSCM4_05579)

LEIN:

94189632(JIQ42_06013)

PHET:

94291289(JKF63_05244)

SGY:

Sgly_1597

ROB:

CK5_28240

BLAB:

EYS05_17015

BLUI:

Blut17040_13890 Blut17040_14910

RTO:

RTO_22660

RGN:	RGna_00050

FGI:	OP10G_0382

SUS:

Acid_0569

PFER:

IRI77_32210

BTH:

BT_2128

BTHO:

Btheta7330_00915(hddA_1)

BFR:

BF2586

BFS:	BF9343_2526

BFG:	BF638R_2601

BFB:	VU15_11545(fkp)

BHL:	Bache_1982

BXY:

BXY_11610

BOA:	Bovatus_02192(hddA_1)

BCEL:

BcellWH2_05118(hddA)

BCAC:

CGC64_18450(fkp)

BCAE:

A4V03_13765(fkp)

BIS:	DXK01_014525(fkp)

BUN:	Bun01g_30610

BFE:	K6V30_25045(fkp)

BNO:	K8P02_12605(fkp)

BFC:	BacF7301_25665(fkp)

BSAL:

K6V25_19695(fkp)

BFIN:

BFINE_57980

BVU:

BVU_1606

BSA:	Bacsa_0234

BDO:	EL88_02950(fkp)

BDH:	GV66_08320(fkp)

PCOP:

I6J50_07580(fkp)

PBT:	ING2E5B_0495

PMUC:

ING2E5A_2839(FUK)

PET:	PEIBARAKI_4442

PSAC:

PSM36_0195

PROJ:

KDN43_10215(fkp)

PDI:

BDI_1573

PARC:

CI960_12140(fkp)

PMER:

INE87_01603

PGOL:

K6V26_04000(fkp)

PJO:	LK449_10460(fkp)

DUN:	FDZ78_02420(fkp)

DUQ:	E7745_13175(fkp)

PII:	NF347_05955

PDT:	Prede_2699

PCOU:

L6468_12135(fkp)

PRU:

PRU_0129

PEO:	AS203_09210(fkp)

ALQ:	C7Y71_002115(fkp)

PCLR:

PC1C4_28300

AIT:	AI2BBH_01730

MCOS:

GM418_23895(fkp)

ASX:	CDL62_10010(fkp)

MGK:	FSB76_14330(fkp)

FBE:	FF125_11410(fkp)

» show all

Reference

1 [PMID:5646162]

Authors

Ishihara H, Heath EC.

Title

The metabolism of L-fucose. IV. The biosynthesis of guanosine diphosphate L-fucose in porcine liver.

Journal

J Biol Chem 243:1110-5 (1968)

Other DBs

ExplorEnz - The Enzyme Database:

2.7.7.30

IUBMB Enzyme Nomenclature:

2.7.7.30

ExPASy - ENZYME nomenclature database:

2.7.7.30

BRENDA, the Enzyme Database:

2.7.7.30

CAS:

9033-14-1

LinkDB

DBGET integrated database retrieval system