KEGG   ENZYME: 2.7.8.47
Entry
EC 2.7.8.47                 Enzyme                                 
Name
teichoic acid ribitol-phosphate polymerase;
Tar polymerase (ambiguous);
tarL (gene name) (ambiguous)
Class
Transferases;
Transferring phosphorus-containing groups;
Transferases for other substituted phosphate groups
Sysname
CDP-ribitol:4-O-[1-D-ribitylphospho-(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol ribitolphosphotransferase
Reaction(IUBMB)
n CDP-ribitol + 4-O-[1-D-ribitylphospho-(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol = n CMP + 4-O-[(1-D-ribitylphospho)n-(1-D-ribitylphospho)-(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol [RN:R11614 R12865]
Reaction(KEGG)
R11614 R12865(G)
Substrate
CDP-ribitol [CPD:C00789];
4-O-[1-D-ribitylphospho-(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol [CPD:C21503]
Product
CMP [CPD:C00055];
4-O-[(1-D-ribitylphospho)n-(1-D-ribitylphospho)-(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol [CPD:C21504]
Comment
Involved in the biosynthesis of teichoic acid linkage units in the cell wall of Bacillus subtilis W23. This enzyme adds the 25-35 ribitol units to the linker molecule.
History
EC 2.7.8.47 created 2017
Pathway
ec00552  Teichoic acid biosynthesis
Orthology
K18704  CDP-ribitol ribitolphosphotransferase / teichoic acid ribitol-phosphate polymerase
Genes
CCON: AFK62_03185
ESC: Entcl_3738
YMA: DA391_06385
BSUN: A4G13_01115
APJ: APJL_1614(cps3A)
VAQ: FIV01_00150(tagB)
PPR: PBPRA2702
ALJ: G8D99_14940
PTN: PTRA_a0500
PPHE: PP2015_409
AAL: EP13_00240
AAUS: EP12_00250
ASP: AOR13_2475
ASQ: AVL57_11050
ALE: AV939_10070
ALZ: AV940_09840
TTI: THITH_00255
HAHE: ENC22_06700
CHAE: CH06BL_44160
CKE: B5M06_15315
HAD: CDV25_02490
CJS: CJS3_1521
CJY: QZ67_01572
CJQ: UC78_1376(tagB)
CJL: PJ17_07560
CJR: CJE1613
CCY: YSS_07705
CCOF: VC76_07105(epsJ_2)
CCOO: ATE51_00688(epsJ_1)
CAVI: CAV_0458
NAM: NAMH_1605
DMA: DMR_40290
DHY: DESAM_20301
DLM: DPPLL_12590
BSL: A7A1_1140
BSY: I653_17460
BSX: C663_3471(tarL)
BSS: BSUW23_17580(tarL)
BST: GYO_3936(tarL)
BIT: BIS30_07550
BHT: DIC78_13170
BMOJ: HC660_34700(tagB)
BTEQ: G4P54_18355 G4P54_18385
BIQ: AN935_18040
BRY: M0696_18145
BJS: MY9_3633
BACY: QF06_16305
BCO: Bcell_3613
BCIR: C2I06_13960
BGI: BGM20_12060
TAID: KS242_14075
VHL: BME96_16450
VIG: BKP57_07895 BKP57_07900
FEC: QNH15_21935
PPSR: I6J18_16025
PRD: F7984_17505 F7984_17510
GAJ: MY490_02505 MY490_02510
FAF: OE104_14490
TEI: QS257_16340
PUK: PU629_01935
SAU: SA0243 SA0247
SAV: SAV0253 SAV0257
SAW: SAHV_0252 SAHV_0256
SAH: SaurJH1_0244 SaurJH1_0248
SAJ: SaurJH9_0238 SaurJH9_0242
SAM: MW0229 MW0233
SAS: SAS0229 SAS0234
SAR: SAR0248 SAR0254
SAC: SACOL0238 SACOL0242
SAX: USA300HOU_0264(tagB1) USA300HOU_0268(tagB2)
SAA: SAUSA300_0247 SAUSA300_0251
SAO: SAOUHSC_00222 SAOUHSC_00227
SAE: NWMN_0187 NWMN_0191
SAD: SAAV_0221 SAAV_0225
SUU: M013TW_0234 M013TW_0238
SUV: SAVC_01005 SAVC_01025
SUE: SAOV_0192 SAOV_0196
SUJ: SAA6159_00230 SAA6159_00234
SUK: SAA6008_00226 SAA6008_00231
SUC: ECTR2_214 ECTR2_218
SUT: SAT0131_00245 SAT0131_00250
SUQ: HMPREF0772_10245 HMPREF0772_10250
SUZ: MS7_0241 MS7_0247
SUD: ST398NM01_0265 ST398NM01_0270
SUX: SAEMRSA15_02120 SAEMRSA15_02160
SUW: SATW20_02550(tarK) SATW20_02590(tarL)
SUG: SAPIG0265 SAPIG0270
SUF: SARLGA251_02170(tarK) SARLGA251_02210(tarL)
SAUA: SAAG_00734 SAAG_00738
SAUE: RSAU_000197 RSAU_000201
SAUN: SAKOR_00230 SAKOR_00236
SAUS: SA40_0211 SA40_0215
SAUU: SA957_0226 SA957_0230
SAUG: SA268_0223 SA268_0227
SAUZ: SAZ172_0255 SAZ172_0260
SAUT: SAI1T1_2001940 SAI1T1_2001980
SAUJ: SAI2T2_1001940 SAI2T2_1001980
SAUK: SAI3T3_1001940 SAI3T3_1001980
SAUQ: SAI4T8_1001940 SAI4T8_1001980
SAUV: SAI7S6_1001940 SAI7S6_1001980
SAUW: SAI5S5_1001930 SAI5S5_1001970
SAUX: SAI6T6_1001940 SAI6T6_1001980
SAUY: SAI8T7_1001940 SAI8T7_1001980
SAUF: X998_0229 X998_0233
SAB: SAB0192 SAB0196
SUY: SA2981_0253 SA2981_0257
SAUB: C248_0240 C248_0245
SAUM: BN843_2520 BN843_2560
SAUC: CA347_260 CA347_264
SAUR: SABB_01595 SABB_01600
SAUI: AZ30_01270 AZ30_01290
SAUD: CH52_04440 CH52_04460
SAMS: NI36_01165 NI36_01185
SUH: SAMSHR1132_02210 SAMSHR1132_02250
SER: SERP0198
SEP: SE_0321
SEPP: SEB_00243
SEPS: DP17_1631
SSP: SSP0356
SCA: SCA_2404
SXY: BE24_10200
SXL: SXYLSMQ121_0384
SXO: SXYL_00387
SSCH: LH95_01800
SEQO: SE1039_21950
SCV: A4G25_08200 A4G25_08205 A4G25_09305
SPET: CEP67_06495 CEP67_08275
SKL: C7J89_03595
SARL: SAP2_04720
SPIC: SAMEA4384060_0081
SSH: NCTC13712_00199(tagF_1) NCTC13712_00203(tagF_3)
SSIM: SAMEA4384339_0090(tagF_1)
SDB: CNQ82_01380
SLLO: ISP08_02340
SPSD: JMB28_02430 JMB28_13565
SCAQ: QMO72_02030(tarL)
SROT: ML435_01080 ML435_01100
STAP: AOB58_2216
SFF: FOB90_06000
NMY: CJ229_008685
LMO: lmo1077 lmo1085
LMN: LM5578_1160 LM5578_1168
LMY: LM5923_1114 LM5923_1122
LMT: LMRG_00539 LMRG_00547
LMOC: LMOSLCC5850_1083 LMOSLCC5850_1091
LMOE: BN418_1295 BN418_1303
LMOB: BN419_1292 BN419_1300
LMOD: LMON_1087 LMON_1095
LMOW: AX10_13965 AX10_14005
LMOQ: LM6179_01397 LM6179_01405
LMR: LMR479A_1105 LMR479A_1113
LMOM: IJ09_04860 IJ09_04900
LMF: LMOf2365_1097
LMC: Lm4b_01096
LMOG: BN389_11100(tarL)
LMP: MUO_05655
LMOL: LMOL312_1077
LMOJ: LM220_05507
LMOZ: LM1816_14202
LMOX: AX24_02805
LMH: LMHCC_1548
LMQ: LMM7_1109
LML: lmo4a_1087
LMG: LMKG_01835 LMKG_01843
LMS: LMLG_2308 LMLG_2568
LMJ: LMOG_00633 LMOG_03302
LMW: LMOSLCC2755_1075 LMOSLCC2755_1083
LMX: LMOSLCC2372_1091 LMOSLCC2372_1099
LMZ: LMOSLCC2482_1120 LMOSLCC2482_1129
LMON: LMOSLCC2376_1050
LMOS: LMOSLCC7179_1058 LMOSLCC7179_1066
LMOO: LMOSLCC2378_1094
LMOY: LMOSLCC2479_1090 LMOSLCC2479_1099
LMOT: LMOSLCC2540_1073 LMOSLCC2540_1082
LMOA: LMOATCC19117_1099
LMOK: CQ02_05615
LMV: Y193_10350
LIN: lin1068
LWE: lwe1060
LSG: lse_0967 lse_0975
LIV: LIV_1026
LII: JL52_05455
LIW: AX25_05545
LIA: JL58_05675
LIO: JL53_06130
LWI: UE46_11760
LGZ: NCTC10812_01040(tagF_3) NCTC10812_01812(tagF_6) NCTC10812_01814(tagF_7) NCTC10812_02004(kfoC_3)
LMAR: LAX80_004980
LNW: OTR81_10215
ESI: Exig_0188
EAN: Eab7_0180(tarL)
EXU: ESP131_03390
EACE: KKI46_01210
PCX: LPB68_14190
PLN: Plano_2232
PDG: BCM40_04090
PHC: BBI08_08415
PGQ: FK545_05100
KUR: ASO14_2499
SPOR: SporoP33_05625
SPOP: SporoP37_06115
RST: ATY39_17025
PANC: E2636_12615
LLK: LLKF_0947(ggaB)
LLX: NCDO2118_0939(ggaB)
LLJ: LG36_1406(ggaB)
LCAR: BHS00_06080
LPL: lp_1819(tarL)
LPJ: JDM1_1532(tagB2)
LPT: zj316_1807(tarL)
LPS: LPST_C1461(tagB2)
LPR: LBP_cg1415
LPZ: Lp16_1408
LPB: SH83_07570
LPX: ASU28_07570
LPG: BB562_08390
LARG: LPA65_07290
PCE: PECL_1837
PIO: PI20285_08410
LEC: LGMK_03545
WCE: WS08_0699
WTR: KHQ32_03755
WCT: WS74_0701
WCI: WS105_0761
WCB: AO080_09205
WJO: FOL01_0725
WHE: EFA59_03560
WVR: IE337_04450
TEY: GLW17_02095
VTE: BHY08_07870
VPI: BW732_01925
CBT: CLH_2994
CLS: CXIVA_01260
CBV: U729_1133
RAL: Rumal_1248
RUS: RBI_I00537 RBI_I01994
ALKA: J0B03_04345
EUU: ADJ67_05825
RIX: RO1_35060
RIM: ROI_04730
RRK: H8S51_015580
BLAB: EYS05_02830
BLAR: LC508_26875
BCOC: BLCOC_40530
LACY: A4V08_21485
HSD: SD1D_2042
EHL: EHLA_1018 EHLA_2957 EHLA_2962 EHLA_3127 EHLA_3144
ERE: EUBREC_2652
LBX: lbkm_2929 lbkm_2930 lbkm_2931
PSOR: RSJ16_02160
KPAR: JL105_07995
AARG: Aargi30884_26940(tagB)
ABSI: A9CBEGH2_00110(tagB)
EBM: SG0102_21250 SG0102_21290
LCG: L3BBH23_26570
ERM: EYR00_06710
CMIT: NQ499_09020
SHI: Shel_14500 Shel_14640
AEQ: AEQU_0651
AHAT: ADCFC_17250
DDT: AAY81_07475
SCYE: R2B67_11495
LXL: KDY119_02610(tarL)
MOO: BWL13_02197(tarL)
MELY: L2X98_21170
MEST: PTQ19_14610
ARN: CGK93_08975
ACIT: HPK19_20705
JDE: Jden_1795
XCE: Xcel_2590
IDO: I598_2371(tagF_2)
PHW: G7075_10605
AEZ: C3E78_05610
AEF: GEV26_05360
MGG: MPLG2_2612(tagB)
BBP: BBPR_0698 BBPR_0699(tagB)
BBI: BBIF_0729 BBIF_0730
BBF: BBB_0690(tarK) BBB_0691
SNG: SNE_A00880
FMO: C4N19_12415
OSP: Odosp_3547
BUY: D8S85_08740
BVIR: I6J59_07105
PIT: PIN17_A0661
POC: NCTC13071_00553 NCTC13071_01724
DOK: MED134_02960
DDO: I597_2601
LUT: Lupro_03965
TRQ: TRQ2_0300
MRU: mru_1079
MSI: Msm_1327
MEB: Abm4_1699
MMIL: sm9_2259
MEYE: TL18_00335
MOL: YLM1_0599
MARO: MarbSA_12200
METV: K4897_04690
MCUB: MCBB_1531(tarL)
HALJ: G9465_17790
 » show all
Reference
1  [PMID:21035733]
  Authors
Brown S, Meredith T, Swoboda J, Walker S
  Title
Staphylococcus aureus and Bacillus subtilis W23 make polyribitol wall teichoic acids using different enzymatic pathways.
  Journal
Chem Biol 17:1101-10 (2010)
DOI:10.1016/j.chembiol.2010.07.017
  Sequence
[bss:BSUW23_17580]
Other DBs
ExplorEnz - The Enzyme Database: 2.7.8.47
IUBMB Enzyme Nomenclature: 2.7.8.47
ExPASy - ENZYME nomenclature database: 2.7.8.47
BRENDA, the Enzyme Database: 2.7.8.47
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