KEGG   ENZYME: 3.1.1.35
Entry
EC 3.1.1.35                 Enzyme                                 
Name
dihydrocoumarin hydrolase
Class
Hydrolases;
Acting on ester bonds;
Carboxylic-ester hydrolases
Sysname
dihydrocoumarin lactonohydrolase
Reaction(IUBMB)
dihydrocoumarin + H2O = melilotate [RN:R03692]
Reaction(KEGG)
R03692
Substrate
dihydrocoumarin [CPD:C02274];
H2O [CPD:C00001]
Product
melilotate [CPD:C01198]
Comment
Also hydrolyses some other benzenoid 1,4-lactones.
History
EC 3.1.1.35 created 1972
Pathway
ec00624  Polycyclic aromatic hydrocarbon degradation
ec00999  Biosynthesis of various plant secondary metabolites
ec01120  Microbial metabolism in diverse environments
Reference
1  [PMID:14458747]
  Authors
KOSUGE T, CONN EE.
  Title
The metabolism of aromatic compounds in higher plants. V. Purification and properties of dihydrocoumarin hydrolase of Melilotus alba.
  Journal
J Biol Chem 237:1653-6 (1962)
Other DBs
ExplorEnz - The Enzyme Database: 3.1.1.35
IUBMB Enzyme Nomenclature: 3.1.1.35
ExPASy - ENZYME nomenclature database: 3.1.1.35
BRENDA, the Enzyme Database: 3.1.1.35
CAS: 37278-47-0
LinkDB

KEGG   REACTION: R03692
Entry
R03692                      Reaction                               
Name
Dihydrocoumarin lactonohydrolase
Definition
Dihydrocoumarin + H2O <=> 3-(2-Hydroxyphenyl)propanoate
Equation
Reaction class
RC00975  C01198_C02274
Enzyme
Pathway
rn00624  Polycyclic aromatic hydrocarbon degradation
rn00999  Biosynthesis of various plant secondary metabolites
rn01120  Microbial metabolism in diverse environments
Other DBs
RHEA: 10363
LinkDB

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